Self-Assembling Myristoylated Human α-Defensin 5 as a Next-Generation Nanobiotics Potentiates Therapeutic Efficacy in Bacterial Infection

ACS Nano ◽  
2018 ◽  
Vol 12 (6) ◽  
pp. 5284-5296 ◽  
Author(s):  
Ruyi Lei ◽  
Jinchao Hou ◽  
Qixing Chen ◽  
Weirong Yuan ◽  
Baoli Cheng ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Therapeutic Efficacy ◽  
Next Generation ◽  
Self Assembling

Therapeutic efficacy of Proteflazid, suppository among the patients with genitourinary viral-bacterial infection

2016 ◽  
pp. 162-166
Author(s):  
V.O. Benyuk ◽  
◽  
O.I. Grinevich ◽  
I.A. Usevich ◽  
I.S. Sikachova ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Therapeutic Efficacy

Tandem Molecular Self-assembly for Selective Lung Cancer Therapy with Two Orders of Magnitude Increase in Efficiency

Nanoscale ◽  
2021 ◽  
Author(s):  
Debin Zheng ◽  
Jingfei Liu ◽  
Yinghao Ding ◽  
Limin Xie ◽  
Yingying Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Anticancer Drugs ◽  
Self Assembly ◽  
Therapeutic Efficacy ◽  
Self Assembling ◽  
Lung Cancer Therapy ◽  
Magnitude Increase

In situ self-assembling of prodrug molecules into nanomedicine can elevate the therapeutic efficacy of anticancer medications by enhancing the targeting and enrichment of anticancer drugs at tumor sites. However, the...

scholarly journals Next Generation Sequencing Reveals the Expression of a Unique miRNA Profile in Response to a Gram-Positive Bacterial Infection

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e57543 ◽  
Author(s):  
Nathan Lawless ◽  
Amir B. K. Foroushani ◽  
Matthew S. McCabe ◽  
Cliona O’Farrelly ◽  
David J. Lynn
Keyword(s):  
Next Generation Sequencing ◽  
Bacterial Infection ◽  
Mirna Profile ◽  
Next Generation ◽  
Gram Positive ◽  
Generation Sequencing

scholarly journals Mapping polyclonal antibody responses to bacterial infection using next generation phage display

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Ibrahim A. Naqid ◽  
Jonathan P. Owen ◽  
Ben C. Maddison ◽  
Anastasios Spiliotopoulos ◽  
Richard D. Emes ◽  
...  
Keyword(s):  
Phage Display ◽  
Bacterial Infection ◽  
Polyclonal Antibody ◽  
Antibody Responses ◽  
Next Generation

scholarly journals Next-generation high-density self-assembling functional protein arrays

2008 ◽  
Vol 5 (6) ◽  
pp. 535-538 ◽  
Author(s):  
Niroshan Ramachandran ◽  
Jacob V Raphael ◽  
Eugenie Hainsworth ◽  
Gokhan Demirkan ◽  
Manuel G Fuentes ◽  
...  
Keyword(s):  
High Density ◽  
Next Generation ◽  
Functional Protein ◽  
Protein Arrays ◽  
Self Assembling

Molecular self-assembly of a tyroservatide-derived octapeptide and hydroxycamptothecin for enhanced therapeutic efficacy

Nanoscale ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 5094-5102
Author(s):  
Jing Liu ◽  
Can Wu ◽  
Guoru Dai ◽  
Feng Feng ◽  
Yuquan Chi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Self Assembly ◽  
Therapeutic Efficacy ◽  
Self Assembling

A pure l-amino acid-based molecular hydrogel was designed through conjugation of an anticancer tripeptide tyroservatide (YSV) with a self-assembling moiety, which enhanced therapeutic efficacy of both YSV and hydroxycamptothecin in vitro and in vivo.

scholarly journals APPLICATION OF SERTACONAZOLE FOR SUPERFICIAL MYCOSES COMPLICATED BY BACTERIAL INFECTION

2014 ◽  
Vol 11 (3) ◽  
pp. 68-72
Author(s):  
I V KHAMAGANOVA ◽  
D F KASHEVAROV
Keyword(s):  
Bacterial Infection ◽  
Therapeutic Efficacy ◽  
Wide Spectrum ◽  
Antiinflammatory Effect ◽  
Superficial Mycoses ◽  
Data Application

Sertaconazole properties are discussed in the article. According to literature data application of the derivation of benzotiafene and imidazole solves a problem of resistance towards antimycotics. Sertaconazole has a wide spectrum of activity towards fungi & bacteria and also has antiinflammatory effect. The present examination of therapeutic efficacy included 33 patients who suffered from superficial mycoses complicated by bacterial infection. Levocetirizine was prescribed in case of dermatomikides. Both monotherapy by sertaconazole and combination with levocetirizine were high effective and well tolerable.

Sign in / Sign up

Export Citation Format

Share Document