Enhancement of Electrochemical Signal on Gold Electrodes by Polyvalent Esterase−Dendrimer Clusters

2008 ◽  
Vol 19 (12) ◽  
pp. 2456-2461 ◽  
Author(s):  
Martin Humenik ◽  
Christopher Pöhlmann ◽  
Yiran Wang ◽  
Mathias Sprinzl
Keyword(s):  
Gold Electrodes ◽  
Electrochemical Signal

Nanostructured mesoporous gold electrodes detect protein phosphorylation in cancer with electrochemical signal amplification

The Analyst ◽  
2020 ◽  
Vol 145 (20) ◽  
pp. 6639-6648 ◽  
Author(s):  
Emtiaz Ahmed ◽  
Mostafa Kamal Masud ◽  
Md. Shahriar A. Hossain ◽  
Jongbeom Na ◽  
Abu Ali Ibn Sina ◽  
...  
Keyword(s):  
Protein Phosphorylation ◽  
Differential Pulse Voltammetry ◽  
Signal Amplification ◽  
Gold Electrode ◽  
Differential Pulse ◽  
Gold Electrodes ◽  
Phosphorylated Protein ◽  
Electrochemical Signal ◽  
Pulse Voltammetry

A nanostructured mesoporous gold electrode is demonstrated to detect the phosphorylated protein over non-phosphorylated in cancer using electrochemical signal amplification through differential pulse voltammetry in the presence of the [Fe(CN)6]3−/4−.

scholarly journals Selective Enhancement of Electrochemical Signal Based on the Size of Alcohols Using Nanoporous Platinum

2021 ◽  
Author(s):  
Jae Jin Bang ◽  
Donghoon Han ◽  
Jinsik Shin ◽  
Taek Dong Chung ◽  
Je Hyun Bae
Keyword(s):  
Electrochemical Signal ◽  
Selective Enhancement ◽  
Nanoporous Platinum

scholarly journals Molecular bridge-mediated ultralow-power gas sensing

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Aishwaryadev Banerjee ◽  
Shakir-Ul Haque Khan ◽  
Samuel Broadbent ◽  
Ashrafuzzaman Bulbul ◽  
Kyeong Heon Kim ◽  
...  
Keyword(s):  
Gas Sensing ◽  
Electron Tunneling ◽  
Gold Surface ◽  
Gold Electrodes ◽  
Self Assembled Monolayer ◽  
Output Resistance ◽  
Resistance Change ◽  
Ultralow Power ◽  
Linker Molecules ◽  
Molecular Bridge

AbstractWe report the electrical detection of captured gases through measurement of the quantum tunneling characteristics of gas-mediated molecular junctions formed across nanogaps. The gas-sensing nanogap device consists of a pair of vertically stacked gold electrodes separated by an insulating 6 nm spacer (~1.5 nm of sputtered α-Si and ~4.5 nm ALD SiO2), which is notched ~10 nm into the stack between the gold electrodes. The exposed gold surface is functionalized with a self-assembled monolayer (SAM) of conjugated thiol linker molecules. When the device is exposed to a target gas (1,5-diaminopentane), the SAM layer electrostatically captures the target gas molecules, forming a molecular bridge across the nanogap. The gas capture lowers the barrier potential for electron tunneling across the notched edge region, from ~5 eV to ~0.9 eV and establishes additional conducting paths for charge transport between the gold electrodes, leading to a substantial decrease in junction resistance. We demonstrated an output resistance change of >108 times upon exposure to 80 ppm diamine target gas as well as ultralow standby power consumption of <15 pW, confirming electron tunneling through molecular bridges for ultralow-power gas sensing.

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

Enzyme-induced Cu2+/Cu+ conversion as the electrochemical signal for sensitive detection of ethyl carbamate

2021 ◽  
Vol 1151 ◽  
pp. 338256
Author(s):  
Long Wu ◽  
Yasheng Wang ◽  
Shuhong Zhou ◽  
Yongheng Zhu ◽  
Xiaoqiang Chen
Keyword(s):  
Ethyl Carbamate ◽  
Sensitive Detection ◽  
Electrochemical Signal
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