Resistance to the Third-Generation Cephalosporin Ceftazidime by a Deacylation-Deficient Mutant of the TEM β-Lactamase by the Uncommon Covalent-Trapping Mechanism

Biochemistry ◽  
2011 ◽  
Vol 50 (29) ◽  
pp. 6387-6395 ◽  
Author(s):  
Nuno T. Antunes ◽  
Hilary Frase ◽  
Marta Toth ◽  
Shahriar Mobashery ◽  
Sergei B. Vakulenko
Keyword(s):  
Generation Cephalosporin ◽  
Third Generation ◽  
Deficient Mutant ◽  
The Third ◽  
Trapping Mechanism ◽  
Covalent Trapping

scholarly journals Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada

1995 ◽  
Vol 6 (2) ◽  
pp. 76-82 ◽  
Author(s):  
Shelley R Scriver ◽  
Canadian Antimicrobial Resistance Study Group ◽  
Donald E Low
Keyword(s):  
Antimicrobial Agents ◽  
Wide Spectrum ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
Beta Lactamase ◽  
Gram Negative ◽  
The Third ◽  
Cephalosporin Resistance ◽  
Third Generation Cephalosporins ◽  
Group 1

In 1992, a surveillance study was performed in Canada to determine the susceptibility of nosocomial Gram-negative rods to several wide spectrum antimicrobials. Consecutive isolates from 10 institutions, as well as additional strains of selected species of Enterobacteriaceae that are known to possess the Bush group 1 beta-lactamase, were tested for susceptibility to 12 antimicrobials. Third-generation cephalosporin resistance was found to be as high as 29% inEnterobacter cloacaethat possesses the Bush group 1 beta-lactamase and less than 4% in those isolates not possessing this enzyme. Cefepime equalled or exceeded the activity of the third-generation cephalosporins against the species of Enterobacteriaceae that demonstrated resistance to the third-generation cephalosporins.

Clinical orientation of the third generation cephalosporin

2012 ◽  
Vol 12 (4) ◽  
pp. 241-248
Author(s):  
XianMin MENG ◽  
YinZhong SHEN ◽  
YongXin ZHANG
Keyword(s):  
Generation Cephalosporin ◽  
Third Generation ◽  
The Third ◽  
Clinical Orientation

scholarly journals Synthesis, Characterization of Ceftibuten-Copper(II) Complex and Prediction of Its Biological Activity

2020 ◽  
Vol 33 (1) ◽  
pp. 190-194
Author(s):  
Shuchismita Dey ◽  
Md. Zakir Sultan ◽  
Md. Abdus Salam
Keyword(s):  
Antibacterial Activity ◽  
Generation Cephalosporin ◽  
Salmonella Typhi ◽  
In Vitro Test ◽  
Third Generation ◽  
The Third ◽  
Vitro Test ◽  
Cephalosporin Antibiotic

Ceftibuten dihydrate, one of the third-generation cephalosporin antibiotic is effectively used in curing several infectious diseases. The complexation of drug with metal may enhance the antibacterial activity. In this work, a new complex of ceftibuten dihydrate with Cu(II) was synthesized, characterized and antibacterial activity is reported. The in vitro test showed that the antibacterial activity of complex of ceftibuten was greatly enhanced against Staphylococcus aureus and Salmonella typhi.

The Third-generation Cephalosporin Ceftazidime

InPharma ◽  
1985 ◽  
Vol 479 (1) ◽  
pp. 16-18
Keyword(s):  
Generation Cephalosporin ◽  
Third Generation ◽  
The Third

scholarly journals THE THIRD-GENERATION CEPHALOSPORIN USE IN A REGIONAL GENERAL HOSPITAL IN INDONESIA

2018 ◽  
Vol 9 (9) ◽  
pp. 41-45 ◽  
Author(s):  
Rika Yulia ◽  
Beatrix Eyleen Giovanny ◽  
Azalia Ayla Khansa ◽  
Sylvia Putri Utami ◽  
Fawandi Fuad Alkindi ◽  
...  
Keyword(s):  
General Hospital ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
The Third

scholarly journals Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable blaDHA-1-carrying plasmid by an ST23 strain

Virulence ◽  
2018 ◽  
Vol 9 (1) ◽  
pp. 838-844 ◽  
Author(s):  
Yingzhou Xie ◽  
Lijun Tian ◽  
Gang Li ◽  
Hongping Qu ◽  
Jingyong Sun ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
The Third

Analysis of Salmonella enterica with Reduced Susceptibility to the Third-Generation Cephalosporin Ceftriaxone Isolated from U.S. Cattle During 2000–2004

2008 ◽  
Vol 14 (4) ◽  
pp. 251-258 ◽  
Author(s):  
Jonathan G. Frye ◽  
Paula J. Fedorka-Cray ◽  
Charlene R. Jackson ◽  
Markus Rose
Keyword(s):  
Salmonella Enterica ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
The Third

scholarly journals Prevalence of ESBL/AmpC genes and specific clones among the third-generation cephalosporin-resistant Enterobacteriaceae from canine and feline clinical specimens in Japan

2018 ◽  
Vol 216 ◽  
pp. 183-189 ◽  
Author(s):  
Yoshihiko Maeyama ◽  
Yui Taniguchi ◽  
Wataru Hayashi ◽  
Yusuke Ohsaki ◽  
Shunsuke Osaka ◽  
...  
Keyword(s):  
Generation Cephalosporin ◽  
Third Generation ◽  
Clinical Specimens ◽  
The Third
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