Nutrient Medium Optimization for Rosmarinic Acid Production by Lavandula vera MM Cell Suspension

2000 ◽  
Vol 16 (4) ◽  
pp. 668-670 ◽  
Author(s):  
A.I. Pavlov ◽  
M.P. Ilieva ◽  
I.N. Panchev
2006 ◽  
Vol 61 (3-4) ◽  
pp. 241-244 ◽  
Author(s):  
Milen Georgiev ◽  
Sonya Kuzeva ◽  
Atanas Pavlov ◽  
Elena Kovacheva ◽  
Mladenka Ilieva

The influence of elicitation on rosmarinic acid biosynthesis by Lavandula vera MM cell suspension culture was investigated using vanadyl sulfate as an abiotic elicitor. It was established that 12 h after treatment with 25 mg/l vanadyl sulfate the rosmarinic acid production was increased up to 3.92 g/l (2.8 times higher compared to the control cultivation). No significant amounts of rosmarinic acid were detected in the culture medium in comparison with its intracellular content. However, it was observed that the extracellular content of rosmarinic acid is 3.3 times higher compared to the control variant (4 h after treatment at elicitor concentration 25 mg/l).


2008 ◽  
Vol 21 (2) ◽  
pp. 394-396 ◽  
Author(s):  
Atanas I. Pavlov ◽  
Milen I. Georgiev ◽  
Ivan N. Panchev ◽  
Mladenka P. Ilieva

2006 ◽  
Vol 23 (2) ◽  
pp. 301-304 ◽  
Author(s):  
Milen I. Georgiev ◽  
Sonya L. Kuzeva ◽  
Atanas I. Pavlov ◽  
Elena G. Kovacheva ◽  
Mladenka P. Ilieva

2008 ◽  
Vol 159 (2) ◽  
pp. 415-425 ◽  
Author(s):  
Milen Georgiev ◽  
Radoslav Abrashev ◽  
Ekaterina Krumova ◽  
Klimentina Demirevska ◽  
Mladenka Ilieva ◽  
...  

2011 ◽  
Vol 108 (1) ◽  
pp. 73-81 ◽  
Author(s):  
Justyna Krzyzanowska ◽  
Anna Czubacka ◽  
Lukasz Pecio ◽  
Marcin Przybys ◽  
Teresa Doroszewska ◽  
...  

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