What's in a Name - Transition State or Critical Transition Structure?

1995 ◽  
Vol 72 (1) ◽  
pp. 13 ◽  
Author(s):  
S. H. Bauer ◽  
C. F. Wilcox
Keyword(s):  
Transition State ◽  
Critical Transition ◽  
Transition Structure

scholarly journals Defining and characterizing the critical transition state prior to the type 2 diabetes disease

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180937 ◽  
Author(s):  
Bo Jin ◽  
Rui Liu ◽  
Shiying Hao ◽  
Zhen Li ◽  
Chunqing Zhu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Transition State ◽  
Critical Transition

scholarly journals Single-Cell Reprogramming in Mouse Embryo Development through a Critical Transition State

Entropy ◽  
2017 ◽  
Vol 19 (11) ◽  
pp. 584 ◽  
Author(s):  
Masa Tsuchiya ◽  
Alessandro Giuliani ◽  
Kenichi Yoshikawa
Keyword(s):  
Transition State ◽  
Single Cell ◽  
Embryo Development ◽  
Mouse Embryo ◽  
Cell Reprogramming ◽  
Critical Transition ◽  
Mouse Embryo Development

A critical transition state in liquid metals

2007 ◽  
Vol 61 (11-12) ◽  
pp. 2434-2438 ◽  
Author(s):  
Yuqin Wu ◽  
Xiufang Bian ◽  
Qingge Meng ◽  
Yan Zhao ◽  
Tan Mao ◽  
...  
Keyword(s):  
Transition State ◽  
Liquid Metals ◽  
Critical Transition

scholarly journals Single-Cell Reprogramming of Mouse Embryo Development Through a Critical Transition State

2017 ◽  
Author(s):  
Masa Tsuchiya ◽  
Alessandro Giuliani ◽  
Kenichi Yoshikawa
Keyword(s):  
Transition State ◽  
Single Cell ◽  
Critical State ◽  
Early Embryo ◽  
Self Organization ◽  
Cell Reprogramming ◽  
Critical Transition ◽  
Critical States ◽  
Oscillatory Dynamics ◽  
Soc Control

AbstractOur work dealing with the temporal development of the genome-expression profile in single-cell mouse early embryo indicated that reprogramming occurs via a critical transition state, where the critical-regulation pattern of the zygote state disappears. In this report, we unveil the detailed mechanism of how the dynamic interaction of thermodynamic states (critical states) enables the genome system to pass through the critical transition state to achieve genome reprogramming.Self-organized criticality (SOC) control of overall expression provides a snapshot of self-organization and explains the coexistence of critical states at a certain experimental time point. The time-development of self-organization is dynamically modulated by exchanges in expression flux between critical states through the cell nucleus milieu, where sequential global perturbations involving activation-inhibition of multiple critical states occur from the early state to the late 2-cell state. Two cyclic fluxes act as feedback flow and generate critical-state coherent oscillatory dynamics. Dynamic perturbation of these cyclic flows due to vivid activation of the ensemble of low-variance expression (sub-critical state) genes allows the genome system to overcome a transition state during reprogramming.Our findings imply that a universal mechanism of long-term global RNA oscillation underlies autonomous SOC control, and the critical gene ensemble at a critical point (CP) drives genome reprogramming. Unveiling the corresponding molecular players will be essential to understand single-cell reprogramming.

Discovering a critical transition state from nonalcoholic hepatosteatosis to nonalcoholic steatohepatitis by lipidomics and dynamical network biomarkers

2016 ◽  
Vol 8 (3) ◽  
pp. 195-206 ◽  
Author(s):  
Rina Sa ◽  
Wanwei Zhang ◽  
Jing Ge ◽  
Xinben Wei ◽  
Yunhua Zhou ◽  
...  
Keyword(s):  
Transition State ◽  
Nonalcoholic Steatohepatitis ◽  
Critical Transition ◽  
Dynamical Network ◽  
Network Biomarkers

scholarly journals Transition state analysis of an enantioselective Michael addition by a bifunctional thiourea organocatalyst

2019 ◽  
Vol 17 (16) ◽  
pp. 3934-3939 ◽  
Author(s):  
Joseph A. Izzo ◽  
Yaroslaw Myshchuk ◽  
Jennifer S. Hirschi ◽  
Mathew J. Vetticatt
Keyword(s):  
Dft Calculations ◽  
Transition State ◽  
Michael Addition ◽  
Transition Structure ◽  
State Analysis

Transition structure for the bifunctional thiourea catalyzed Michael addition using 13C KIEs and DFT calculations.

scholarly journals Genome-wide dynamic network analysis reveals a critical transition state of flower development in Arabidopsis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Fuping Zhang ◽  
Xiaoping Liu ◽  
Aidi Zhang ◽  
Zhonglin Jiang ◽  
Luonan Chen ◽  
...  
Keyword(s):  
Network Analysis ◽  
Transition State ◽  
Flower Development ◽  
Dynamic Network ◽  
Critical Transition ◽  
Dynamic Network Analysis ◽  
Genome Wide

Rheology of the Critical Transition State of an Epoxy Vitrimer

2020 ◽  
Vol 53 (12) ◽  
pp. 4855-4862 ◽  
Author(s):  
Huagao Fang ◽  
Wujin Ye ◽  
Yunsheng Ding ◽  
H. Henning Winter
Keyword(s):  
Transition State ◽  
Critical Transition

scholarly journals Can Aromaticity of Fused Aromatic Ring in 1,3-Pentadiene Modulate its Reactivity towards [1,5]-Halo Shift? - A DFT Study

2021 ◽  
Vol 33 (2) ◽  
pp. 447-452
Author(s):  
Padmanaban Kalpana ◽  
Lakshminarayanan Akilandeswari
Keyword(s):  
Transition State ◽  
Aromatic Ring ◽  
Driving Force ◽  
Reaction Pathway ◽  
The Other ◽  
Transition Structure ◽  
Activation Barriers ◽  
Aromaticity Index ◽  
Pericyclic Reaction

In (Z)-1,3-pentadienes, [1,5]-H migration is suprafacially allowed while fluorine shift in this system takes place by a Contra Hoffmann antarafacial pathway for which aromaticity is the driving force. If aromaticity of the transition structure (TS) can drive a reaction towards a disallowed pathway as found in the case of fluorine, the role of aromatic ring annealed to (Z)-1,3-pentadienes in determining the reaction pathway and barrier is worth noting. Hence, the combined role of aromaticity of transition state and the loss in aromaticity of the annealed ring has been explored during the [1,5]-X (X = H, F, Cl, Br) shifts in aromatic (benzene/naphthalene) annealed 1,3-pentadiene system. Notable correlations between various aromaticity index NICS(0,1) with activation barriers show that aromaticity of transition structure in pericyclic reaction can drive the stereochemical course of a reaction. The distinct effect of fluorine to other halogens is the antara migration while the other halogens (Cl & Br) prefer supramode.

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