Dietary Exposure Assessment of Chinese Adults and Nursing Infants to Tetrabromobisphenol-A and Hexabromocyclododecanes: Occurrence Measurements in Foods and Human Milk

2009 ◽  
Vol 43 (12) ◽  
pp. 4314-4319 ◽  
Author(s):  
Zhi-Xiong Shi ◽  
Yong-Ning Wu ◽  
Jing-Guang Li ◽  
Yun-Feng Zhao ◽  
Jin-Fang Feng
Keyword(s):  
Human Milk ◽  
Exposure Assessment ◽  
Dietary Exposure ◽  
Tetrabromobisphenol A ◽  
Chinese Adults

scholarly journals The Abundance of Human Milk Oligosaccharide (HMO)-Metabolizing Genes in Fecal Samples from Six-Month-Old Human Infants

2021 ◽  
Vol 9 (7) ◽  
pp. 1352
Author(s):  
Lynn E. Ferro ◽  
Kameron Y. Sugino ◽  
Vanja Klepac-Ceraj ◽  
Sarah S. Comstock
Keyword(s):  
Human Milk ◽  
Mode Of Delivery ◽  
Dietary Exposure ◽  
Quantitative Real Time Pcr ◽  
Human Infants ◽  
Fecal Samples ◽  
Gene Abundance ◽  
Development And Validation ◽  
Biology Laboratory ◽  
Further Development

Herein, we report the abundance and prevalence of HMO-metabolizing genes, specifically those of Bifidobacterium infantis, in fecal samples from human infants. Forty dyads were enrolled, and each mother collected a fecal sample from her infant at six months of age. Genomic DNA was extracted, and quantitative real-time PCR was used to determine gene abundance. The mode of delivery was not associated with gene abundance. Several gene regions, Sia (a sialidase), B. inf (16S), and GH750 (a glycoside hydrolase), were more abundant in the feces of human milk-fed infants (p < 0.05). Others, Sia and HC bin (16S), tended to be less abundant when a larger percentage of an infant’s diet consisted of solids (p < 0.10). When accounting for solid food intake, human milk exposure was positively associated with Sia and B. inf (p < 0.05) and tended to be related to the abundance of the GH750 and HC bin (p < 0.10) gene regions. With further development and validation in additional populations of infants, these assays could be used to group samples by dietary exposure even where no record of dietary intake exists. Thus, these assays would provide a method by which infant human milk intake can be assessed quickly in any well-equipped molecular biology laboratory.

Dietary exposure assessment of β-glucan in a barley and oat based bread

LWT ◽  
2012 ◽  
Vol 47 (2) ◽  
pp. 413-420 ◽  
Author(s):  
U. Tiwari ◽  
E. Cummins
Keyword(s):  
Exposure Assessment ◽  
Dietary Exposure
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