Preferential Fragmentation of Protonated Gas-Phase Peptide Ions Adjacent to Acidic Amino Acid Residues

1995 ◽  
Vol 117 (19) ◽  
pp. 5411-5412 ◽  
Author(s):  
Jun Qin ◽  
Brian T. Chait
Keyword(s):  
Amino Acid ◽  
Gas Phase ◽  
Amino Acid Residues ◽  
Peptide Ions ◽  
Acidic Amino Acid

Volumes of Individual Amino Acid Residues in Gas-Phase Peptide Ions

1999 ◽  
Vol 121 (16) ◽  
pp. 4031-4039 ◽  
Author(s):  
Anne E. Counterman ◽  
David E. Clemmer
Keyword(s):  
Amino Acid ◽  
Gas Phase ◽  
Individual Amino Acid ◽  
Amino Acid Residues ◽  
Peptide Ions

Novel Peptide Dissociation:  Gas-Phase Intramolecular Rearrangement of Internal Amino Acid Residues

1997 ◽  
Vol 119 (24) ◽  
pp. 5481-5488 ◽  
Author(s):  
Richard W. Vachet ◽  
Barney M. Bishop ◽  
Bruce W. Erickson ◽  
Gary L. Glish
Keyword(s):  
Amino Acid ◽  
Gas Phase ◽  
Intramolecular Rearrangement ◽  
Amino Acid Residues ◽  
Peptide Dissociation

Involvement of Acidic Amino Acid Residues in Zn2+Binding to Respiratory Complex I

ChemBioChem ◽  
2015 ◽  
Vol 16 (14) ◽  
pp. 2080-2085 ◽  
Author(s):  
Sébastien Kriegel ◽  
Batoul Srour ◽  
Stefan Steimle ◽  
Thorsten Friedrich ◽  
Petra Hellwig
Keyword(s):  
Amino Acid ◽  
Complex I ◽  
Amino Acid Residues ◽  
Acidic Amino Acid ◽  
Respiratory Complex ◽  
Respiratory Complex I

scholarly journals Role of Integrase in Reverse Transcription of the Saccharomyces cerevisiae Retrotransposon Ty1

2005 ◽  
Vol 4 (6) ◽  
pp. 1057-1065 ◽  
Author(s):  
M. Wilhelm ◽  
F.-X. Wilhelm
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Amino Acid ◽  
Specific Activity ◽  
Rnase H ◽  
Amino Acid Residues ◽  
Acidic Amino Acid ◽  
Acidic Domain ◽  
Basic Region

ABSTRACT Reverse transcriptase (RT) with its associated RNase H (RH) domain and integrase (IN) are key enzymes encoded by retroviruses and retrotransposons. Several studies have implied a functional role of the interaction between IN and RT during the replication of retroviral and retrotransposon genomes. In this study, IN deletion mutants were used to investigate the role of IN on the RT activity of the yeast Saccharomyces cerevisiae retrotransposon Ty1. We have identified two domains of Ty1 integrase which have effects on RT activity in vivo. The deletion of a domain spanning amino acid residues 233 to 520 of IN increases the exogenous specific activity of RT up to 20-fold, whereas the removal of a region rich in acidic amino acid residues between residues 521 and 607 decreases its activity. The last result complements our observation that an active recombinant RT protein can be obtained if a small acidic tail mimicking the acidic domain of IN is fused to the RT-RH domain. We suggest that interaction between these acidic amino acid residues of IN and a basic region of RT could be critical for the correct folding of RT and for the formation of an active conformation of the enzyme.

scholarly journals Conserved Acidic Amino Acid Residues in a Second RNA Recognition Motif Regulate Assembly and Function of TDP-43

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e52776 ◽  
Author(s):  
Akemi Shodai ◽  
Akemi Ido ◽  
Noriko Fujiwara ◽  
Takashi Ayaki ◽  
Toshifumi Morimura ◽  
...  
Keyword(s):  
Amino Acid ◽  
Rna Recognition Motif ◽  
Rna Recognition ◽  
Amino Acid Residues ◽  
Acidic Amino Acid ◽  
Recognition Motif ◽  
And Function
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