Kinetics of competitive-consecutive second-order reactions involving difunctional unsymmetrical molecules. Kinetics of the alkaline hydrolysis of diethyl malate

In order to get basic data for the design of a novel treatment scheme for high explosives we investigated the kinetics for the aqueous alkaline hydrolysis of 1,3,5,7-tetraaza-1,3,5,7-tetranitrocyclooctane (HMX) and the temperature dependence of the rate constants. We used an HPLC procedure for the analysis of HMX. All experimental data could be fit accurately to a pseudo first-order rate equation and subsequent calculation of second-order rate constants was also precise. Temperature dependence could be modeled with the Arrhenius equation. An increase of 10°C led to an average increase in the second-order rate constants by the 3.16 fold. The activation energy of the second-order reaction was determined to be 111.9 ±0.76 kJ·moJ‒1. We found the alkaline hydrolysis to be rapid (less than 2.5% of the initial HMX-concentration left after 100 minutes) at base concentrations of 23 mmol oH‒/L and elevated temperatures between 60 and 80°C.

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Kinetics of twelve-step competitive-consecutive second-order reactions. Alkaline hydrolysis of triethyl citrate

The Journal of Physical Chemistry ◽

10.1021/j100631a014 ◽

1973 ◽

Vol 77 (12) ◽

pp. 1552-1557 ◽

Cited By ~ 2

Author(s):

F. A. Kundell ◽

D. J. Robinson ◽

W. J. Svirbely

Keyword(s):

Alkaline Hydrolysis ◽

Second Order ◽

Twelve Step ◽

Triethyl Citrate ◽

Kinetics Of ◽

Hydrolysis Of

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Influence of medium on alkaline hydrolysis of succinic acid monomethyl and monopropyl esters

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19802873 ◽

1980 ◽

Vol 45 (11) ◽

pp. 2873-2882

Author(s):

Vladislav Holba ◽

Ján Benko

Keyword(s):

Succinic Acid ◽

Kinetic Parameters ◽

Alkaline Hydrolysis ◽

Specific Interactions ◽

Nonaqueous Media ◽

The Media ◽

Kinetics Of ◽

Hydrolysis Of

The kinetics of alkaline hydrolysis of succinic acid monomethyl and monopropyl esters were studied in mixed aqueous-nonaqueous media at various temperatures and ionic strengths. The results of measurements are discussed in terms of electrostatic and specific interactions between the reactants and other components of the reaction mixture. The kinetic parameters in the media under study are related to the influence of the cosolvent on the solvation sphere of the reactants.

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The Kinetics of the Acidic and Alkaline Hydrolysis of Ethyl Thionbenzoate

The Journal of Organic Chemistry ◽

10.1021/jo01045a081 ◽

1963 ◽

Vol 28 (10) ◽

pp. 2825-2828 ◽

Cited By ~ 7

Author(s):

Stanley G. Smith ◽

Marion O'Leary

Keyword(s):

Alkaline Hydrolysis ◽

Kinetics Of ◽

Hydrolysis Of

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Isothermal and non-isothermal kinetics of hydrolysis of 1-[2-(2- pentyloxyphenylcarbamoyloxy)-(2-methoxymethyl)-ethyl]- perhydroazepinium chloride (BK 129)

Acta Facultatis Pharmaceuticae Universitatis Comenianae ◽

10.2478/afpuc-2013-0018 ◽

2013 ◽

Vol 60 (2) ◽

pp. 43-48

Author(s):

Stankovičová M. ◽

Bezáková Ž. ◽

Beňo P. ◽

Húšťavová P.

Keyword(s):

Biological Activity ◽

Alkaline Hydrolysis ◽

Functional Group ◽

Isothermal Kinetics ◽

Basic Part ◽

Buffer Solutions ◽

Kinetics Of Hydrolysis ◽

Short Time ◽

Kinetics Of ◽

Hydrolysis Of

Abstract The substance BK 129 - 1-[2-(2-pentyloxyphenylcarbamoyloxy)-(2-methoxymethyl)-ethyl]-perhydroazepinium chloride was prepared in terms of influence of the connecting chain between the carbamate functional group and the basic part of molecule on biological activity. Such a structural feature is important with regard to its stability. In this work we determined the rate constants of alkaline hydrolysis of this compound at increased temperature under isothermal and non-isothermal conditions. The hydrolysis was also performed in buffer solutions with the purpose of evaluating its stability. Non-isothermal tests of stability enable to reduce the number of analyses. The necessary data for stability of compound are in this way achieved in a short time.

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