scholarly journals Functional-Group-Tolerant, Nickel-Catalyzed Cross-Coupling Reaction for Enantioselective Construction of Tertiary Methyl-Bearing Stereocenters

2013 ◽  
Vol 135 (24) ◽  
pp. 9083-9090 ◽  
Author(s):  
Hanna M. Wisniewska ◽  
Elizabeth C. Swift ◽  
Elizabeth R. Jarvo
Keyword(s):  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cross Coupling Reaction ◽  
Tertiary Methyl

scholarly journals Suzuki–Miyaura cross-coupling reaction on copper-trans-A2B corroles with excellent functional group tolerance

Tetrahedron ◽  
2011 ◽  
Vol 67 (23) ◽  
pp. 4243-4252 ◽  
Author(s):  
Michael König ◽  
Lorenz Michael Reith ◽  
Uwe Monkowius ◽  
Günther Knör ◽  
Klaus Bretterbauer ◽  
...  
Keyword(s):  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cross Coupling Reaction

Metal-free cross-coupling reaction of aldehydes with disulfides by using DTBP as an oxidant under solvent-free conditions

2014 ◽  
Vol 16 (5) ◽  
pp. 2644-2652 ◽  
Author(s):  
Jing-Wen Zeng ◽  
Yi-Chen Liu ◽  
Ping-An Hsieh ◽  
Yu-Ting Huang ◽  
Chih-Lun Yi ◽  
...  
Keyword(s):  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Solvent Free ◽  
Metal Free ◽  
Cross Coupling Reaction ◽  
Solvent Free Conditions

A DTBP-promoted C–H thiolation of aldehydes with disulfides under metal-free and solvent-free conditions is described. The system shows good functional group tolerance to afford thioesters in moderate to excellent yields.

Iron-Catalysed Regioselective Arylsulfonylation of Quinoline N-Oxides with Sodium Arylsulfinates under Microwave Irradiation

2017 ◽  
Vol 41 (12) ◽  
pp. 705-708 ◽  
Author(s):  
Wenpeng Mai ◽  
Mingxiu Lv ◽  
Xiaofeng Zhang ◽  
Kui Lu
Keyword(s):  
Microwave Irradiation ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Regioselective Synthesis ◽  
One Pot ◽  
Cross Coupling Reaction

An efficient protocol for one-pot deoxygenative and regioselective synthesis of 2-arylsulfonylquinolines has been developed via iron-catalysed cross-coupling reaction of quinoline N-oxides with sodium arylsulfinates in moderate to good yields under microwave irradiation. The reactions proceeded over a broad range of substrates with good regioselectivity and functional group tolerance.

Dimerization of Aromatic Compounds Using Palladium-Carbon-Catalyzed Suzuki–Miyaura Cross-Coupling by One-Pot Synthesis

Synlett ◽  
2018 ◽  
Vol 29 (06) ◽  
pp. 779-784 ◽  
Author(s):  
Guoliang Chen ◽  
Fangyu Du ◽  
Qifan Zhou ◽  
Dongdong Liu ◽  
Ting Fang ◽  
...  
Keyword(s):  
Aromatic Compounds ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Potassium Acetate ◽  
Carbon Catalyst ◽  
Reaction Conditions ◽  
One Pot ◽  
Cross Coupling Reaction ◽  
High Yields

The aromatic dimers play a significant role in many aspects. Herein, we report a simple palladium-carbon catalyst that is highly effective for the dimerization of brominated aromatic compounds under mild conditions using abundant brominated aromatic compounds, bis(pinacolate)diboron and potassium acetate by a ‘one-pot’ method. This process, which we believe proceeds via a Suzuki–Miyaura cross-coupling reaction mechanism, allows access to a variety of aromatic compounds under mild reaction conditions and has a good functional group tolerance with moderate to high yields.

Highly Efficient Copper-Catalyzed Dehydrogenative Cross-Coupling of Azoles and α-Amino Carbonyl Compounds

Synthesis ◽  
2020 ◽  
Author(s):  
Jiu-Jian Ji ◽  
Zhi-Qiang Zhu ◽  
Zong-Bo Xie ◽  
Juan Tang ◽  
En Yuan ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Synthetic Method ◽  
Diverse Range ◽  
Highly Efficient ◽  
Cross Coupling Reaction ◽  
Butyl Peroxide ◽  
High Yields

A novel and highly efficient dehydrogenative cross-coupling reaction between α-amino carbonyl compounds and azoles by copper catalysis using di-tert-butyl peroxide (DTBP) as an oxidant was described. A diverse range of azoles underwent the dehydrogenative imidoylation smoothly with various α-amino carbonyl compounds for the exclusive formation of the corresponding N-imidoyl azoles in high yields under air. The synthetic method has the advantages of good functional-group tolerance, wide substrate scope, excellent yields and simple operation, thus providing a convenient and practical protocol for the synthesis of various functionalized azoles.

scholarly journals Organozinc-mediated direct cross-coupling under microwave irradiation

2021 ◽  
pp. 174751982110264
Author(s):  
Chun-Jing Li
Keyword(s):  
Microwave Irradiation ◽  
Functional Group ◽  
Bond Cleavage ◽  
Reaction Times ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cross Coupling Reaction ◽  
Direct Cross ◽  
Methyl Pyrrolidone ◽  
Work Up

We report a direct cross-coupling reaction between (het)aryl pivalates/tosylates and di(het)arylzinc species in 2-methyltetrahydrofuran/ N-methyl pyrrolidone (1:1), which occurs via C–O bond cleavage under microwave irradiation. The reaction takes place smoothly in short reaction times without the addition of any catalyst or ligand. The reaction is suitable for a broad scope of substrates and exhibits good functional group compatibility, utilizes a simple work-up procedure, and gives the desired products in high purity.

Metal-free catalyzed arylsulfonylation of chloroquinoline with sodium arylsulfinates under microwave irradiation

2018 ◽  
Vol 73 (5) ◽  
pp. 295-303 ◽  
Author(s):  
Xi-Yong Li ◽  
Ya-Min Sun ◽  
Jin-Wei Yuan
Keyword(s):  
Microwave Irradiation ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Free ◽  
Cross Coupling Reaction ◽  
Wide Range

AbstractAn efficient protocol for the synthesis of 2-arylsulfonyl quinolines has been developed via a metal-free catalyzed cross-coupling reaction of chloroquinoline with sodium arylsulfinates in moderate-to-good yields under microwave irradiation. The reactions proceed with a wide range of substrates with good functional group tolerance.

Palladium-Catalyzed Decarboxylation of Benzyl Fluorobenzoates

Synlett ◽  
2017 ◽  
Vol 28 (19) ◽  
pp. 2573-2576 ◽  
Author(s):  
Ryoichi Kuwano ◽  
Yusuke Makida ◽  
Yasutaka Matsumoto
Keyword(s):  
Benzoic Acid ◽  
Catalytic Reaction ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Benzoic Acids ◽  
Benzyl Alcohols ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed

The decarboxylation of benzyl fluorobenzoates has been developed by using the palladium catalyst prepared in situ from Pd(η3-allyl)Cp and bulky monophosphine ligand XPhos. The catalytic reaction afforded a range of fluorinated diarylmethanes in good yields with broad functional-group compatibility. The substrates were readily synthesized by condensation of the corresponding benzoic acid with benzyl alcohol. Therefore, the transformation is formally regarded as a cross-coupling reaction between fluorine-containing benzoic acids and benzyl alcohols.

Functional Group Tolerance of a Micellar on-DNA Suzuki–Miyaura Cross-Coupling Reaction for DNA-Encoded Library Design

2021 ◽  
Author(s):  
James H. Hunter ◽  
Marco Potowski ◽  
Harriet A. Stanway-Gordon ◽  
Andrew Madin ◽  
Garry Pairaudeau ◽  
...  
Keyword(s):  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Library Design ◽  
Cross Coupling Reaction

A systematic study on the Cadiot–Chodkiewicz cross coupling reaction for the selective and efficient synthesis of hetero-diynes

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 54449-54455 ◽  
Author(s):  
Bhavani Shankar Chinta ◽  
Beeraiah Baire
Keyword(s):  
Systematic Study ◽  
Functional Group ◽  
Reaction Medium ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Green Solvent ◽  
Efficient Synthesis ◽  
Solvent Water ◽  
Cross Coupling Reaction ◽  
Basic Reaction

99% selectivity for cross coupling. Excellent yields (upto 94%). Low basic reaction medium, high functional group tolerance. Use of green solvent water.

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