Characterization of Synthetic Peptide Therapeutics Using Liquid Chromatography–Mass Spectrometry: Challenges, Solutions, Pitfalls, and Future Perspectives

Journal of the American Society for Mass Spectrometry ◽

10.1021/jasms.0c00479 ◽

2021 ◽

Author(s):

Zhirui Lian ◽

Ning Wang ◽

Yuwei Tian ◽

Lihua Huang

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Synthetic Peptide ◽

Liquid Chromatography Mass Spectrometry ◽

Future Perspectives ◽

Peptide Therapeutics ◽

Chromatography Mass Spectrometry

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Faculty Opinions recommendation of Investigating the in vitro metabolism of fipexide: characterization of reactive metabolites using liquid chromatography/mass spectrometry.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088147.541144 ◽

2007 ◽

Author(s):

Gary Rankin

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

In Vitro Metabolism ◽

Reactive Metabolites ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry

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Characterization of theMycobacterium tuberculosisProteome by Liquid Chromatography Mass Spectrometry-based Proteomics Techniques: A Comprehensive Resource for Tuberculosis Research

Journal of Proteome Research ◽

10.1021/pr2007939 ◽

2011 ◽

Vol 11 (1) ◽

pp. 119-130 ◽

Author(s):

Christina Bell ◽

Geoffrey T. Smith ◽

Michael J. Sweredoski ◽

Sonja Hess

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry

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Characterization of Groundwater Samples from Superfund Sites by Gas Chromatography/Mass Spectrometry and Liquid Chromatography/Mass Spectrometry

Environmental Science & Technology ◽

10.1021/es9602206 ◽

1996 ◽

Vol 30 (12) ◽

pp. 3558-3564 ◽

Author(s):

Leon D. Betowski ◽

Douglas S. Kendall ◽

Christopher M. Pace ◽

Joseph R. Donnelly

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Liquid Chromatography ◽

Gas Chromatography Mass Spectrometry ◽

Liquid Chromatography Mass Spectrometry ◽

Superfund Sites ◽

Chromatography Mass Spectrometry ◽

Groundwater Samples

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Characterization of Phytoplankton Communities in Response to Macronutrient Treatments Determined by High-Performance Liquid Chromatography Mass Spectrometry

Analytical Letters ◽

10.1080/00032719.2015.1122029 ◽

2016 ◽

Vol 49 (11) ◽

pp. 1758-1771

Author(s):

Qijun Luo ◽

Yue Song ◽

Liyang Zheng ◽

Juanjuan Chen ◽

Jilin Xu ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Phytoplankton Communities

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Characterization of glycopeptides from HIV-ISF2 gp120 by liquid chromatography mass spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2004.07.008 ◽

2004 ◽

Vol 15 (11) ◽

pp. 1545-1555 ◽

Author(s):

Jenny M. Cutalo ◽

Leesa J. Deterding ◽

Kenneth B. Tomer

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry

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Orthogonal liquid chromatography–mass spectrometry methods for the comprehensive characterization of therapeutic glycoproteins, from released glycans to intact protein level

Journal of Chromatography A ◽

10.1016/j.chroma.2017.02.072 ◽

2017 ◽

Vol 1498 ◽

pp. 128-146 ◽

Author(s):

Eric Largy ◽

Fabrice Cantais ◽

Géry Van Vyncht ◽

Alain Beck ◽

Arnaud Delobel

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Protein Level ◽

Intact Protein ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Comprehensive Characterization ◽

Therapeutic Glycoproteins

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Integrated liquid chromatography-mass spectrometry and nuclear magnetic resonance spectra for the comprehensive characterization of various components in the Shuxuening injection

Journal of Chromatography A ◽

10.1016/j.chroma.2019.04.008 ◽

2019 ◽

Vol 1599 ◽

pp. 125-135 ◽

Author(s):

Shuting Yu ◽

Jing Li ◽

Liang Guo ◽

Caixia Di ◽

Xuemei Qin ◽

...

Keyword(s):

Mass Spectrometry ◽

Nuclear Magnetic Resonance ◽

Liquid Chromatography ◽

Magnetic Resonance ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Nuclear Magnetic Resonance Spectra ◽

Comprehensive Characterization ◽

Magnetic Resonance Spectra

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Characterization of medicinal plant-associated biocontrol Bacillus subtilis (SSL2) by liquid chromatography-mass spectrometry and evaluation of compounds by in silico and in vitro methods

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2019.1581091 ◽

2019 ◽

Vol 38 (2) ◽

pp. 500-510 ◽

Author(s):

Hardik Naik Jinal ◽

Natarajan Amaresan

Keyword(s):

Mass Spectrometry ◽

Bacillus Subtilis ◽

Liquid Chromatography ◽

Medicinal Plant ◽

In Silico ◽

Liquid Chromatography Mass Spectrometry ◽

In Vitro Methods ◽

Chromatography Mass Spectrometry

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A rapid approach for characterization of thiol-conjugated antibody–drug conjugates and calculation of drug–antibody ratio by liquid chromatography mass spectrometry

Analytical Biochemistry ◽

10.1016/j.ab.2015.06.001 ◽

2015 ◽

Vol 485 ◽

pp. 34-42 ◽

Author(s):

David Firth ◽

Leonard Bell ◽

Martin Squires ◽

Sian Estdale ◽

Colin McKee

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Liquid Chromatography Mass Spectrometry ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Chromatography Mass Spectrometry ◽

Drug Antibody Ratio ◽

Antibody Ratio ◽

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Liquid chromatography–mass spectrometry structural characterization of neo glycoproteins aiding the rational design and synthesis of a novel glycovaccine for protection against tuberculosis

Journal of Chromatography A ◽

10.1016/j.chroma.2014.09.041 ◽

2014 ◽

Vol 1367 ◽

pp. 57-67 ◽

Author(s):

Caterina Temporini ◽

Teodora Bavaro ◽

Sara Tengattini ◽

Immacolata Serra ◽

Giorgio Marrubini ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Structural Characterization ◽

Rational Design ◽

Liquid Chromatography Mass Spectrometry ◽

Design And Synthesis ◽

Chromatography Mass Spectrometry

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