The Design and Synthesis of Water-Soluble Analogues of CB30865, a Quinazolin-4-one-Based Antitumor Agent

2002 ◽  
Vol 45 (17) ◽  
pp. 3692-3702 ◽  
Author(s):  
V. Bavetsias ◽  
L. A. Skelton ◽  
F. Yafai ◽  
F. Mitchell ◽  
S. C. Wilson ◽  
...  
Keyword(s):  
Antitumor Agent ◽  
Water Soluble ◽  
Design And Synthesis

ChemInform Abstract: The Design and Synthesis of Water-Soluble Analogues of CB30865, a Quinazolin-4-one-Based Antitumor Agent.

ChemInform ◽  
2010 ◽  
Vol 33 (52) ◽  
pp. no-no
Author(s):  
V. Bavetsias ◽  
L. A. Skelton ◽  
F. Yafai ◽  
F. Mitchell ◽  
S. C. Wilson ◽  
...  
Keyword(s):  
Antitumor Agent ◽  
Water Soluble ◽  
Design And Synthesis

Design and Synthesis of Highly Luminescent Near-Infrared-Emitting Water-Soluble CdTe/CdSe/ZnS Core/Shell/Shell Quantum Dots

2009 ◽  
Vol 48 (20) ◽  
pp. 9723-9731 ◽  
Author(s):  
Wenjin Zhang ◽  
Guanjiao Chen ◽  
Jian Wang ◽  
Bang-Ce Ye ◽  
Xinhua Zhong
Keyword(s):  
Quantum Dots ◽  
Near Infrared ◽  
Water Soluble ◽  
Core Shell ◽  
Design And Synthesis

Design and synthesis of novel water-soluble amino acid derivatives of chlorin p6 ethers as photosensitizer

2019 ◽  
Vol 30 (1) ◽  
pp. 247-249 ◽  
Author(s):  
Xingjie Zhang ◽  
Zhi Meng ◽  
Zhiqiang Ma ◽  
Junhong Liu ◽  
Guiyan Han ◽  
...  
Keyword(s):  
Amino Acid ◽  
Water Soluble ◽  
Amino Acid Derivatives ◽  
Design And Synthesis ◽  
Derivatives Of ◽  
Chlorin P6

Fundamentals of Transarterial Embolization Technique by Drug-Delivery Embolic Emulsion

1997 ◽  
Vol 3 (2_suppl) ◽  
pp. 106-109
Author(s):  
M. Ikeda ◽  
K. Shimoyamada ◽  
N. Katayama ◽  
T. Itoh ◽  
K. Takahashi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Pulmonary Embolism ◽  
Transarterial Embolization ◽  
Antitumor Agent ◽  
Water Soluble ◽  
Malignant Neoplasms ◽  
Water Soluble Contrast ◽  
Additional Water ◽  
Contrast Materials

We developed new embolic drug delivery emulsions to be utilized for malignant neoplasms. We combined additional water-soluble contrast materials (Ioxaglic acid, Iopamidol) with Glyceol, Poloxamer-188, or D-Mannitol to antitumor agent Lipiodol ultrafluid in order to generate stable emulsions. Some of these emulsions have been shown to cause pulmonary embolism in rabbits and to allow gradual diffusion of the antitumor agent in vitro. Good therapeutic utility is indicated. In particular, one emulsion containing D-Mannitol (Mizonokuchi emulsion), is expected to prolong drug delivery in malignant brain tumors.

Design and synthesis of novel enhanced water soluble hydroxyethyl analogs of combretastatin A-4

2011 ◽  
Vol 21 (7) ◽  
pp. 2087-2091 ◽  
Author(s):  
Megan Lee ◽  
Olivia Brockway ◽  
Armaan Dandavati ◽  
Samuel Tzou ◽  
Robert Sjoholm ◽  
...  
Keyword(s):  
Water Soluble ◽  
Design And Synthesis

ChemInform Abstract: Design and Synthesis of a Novel Water Soluble Benzotetrazepinone.

ChemInform ◽  
2001 ◽  
Vol 32 (4) ◽  
pp. no-no
Author(s):  
Beatrice Dumont-Hornebeck ◽  
Yi Ning Strube ◽  
Daniela Vasilescu ◽  
Bertrand Jacques Jean-Claude
Keyword(s):  
Water Soluble ◽  
Design And Synthesis

A Novel Approach of Water-Soluble Paclitaxel Prodrug with No Auxiliary and No Byproduct:  Design and Synthesis of Isotaxel

2003 ◽  
Vol 46 (18) ◽  
pp. 3782-3784 ◽  
Author(s):  
Yoshio Hayashi ◽  
Mariusz Skwarczynski ◽  
Yoshio Hamada ◽  
Youhei Sohma ◽  
Tooru Kimura ◽  
...  
Keyword(s):  
Water Soluble ◽  
Design And Synthesis ◽  
Novel Approach

The Rational Design and Synthesis of Water-Soluble Thiourea Ligands for Recoverable Pd-Catalyzed Aerobic Aqueous Suzuki–Miyaura Reactions at Room Temperature

Synthesis ◽  
2018 ◽  
Vol 50 (07) ◽  
pp. 1499-1510 ◽  
Author(s):  
Wei Chen ◽  
Xiao-Yan Lu ◽  
Bei-Hua Xu ◽  
Wei-guo Yu ◽  
Zi-niu Zhou ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Rational Design ◽  
Pd Nanoparticles ◽  
Water Soluble ◽  
Tem Analysis ◽  
Arylboronic Acids ◽  
Design And Synthesis ◽  
Black Precipitate ◽  
Aryl Bromides ◽  
Carboxylic Groups

Eight precatalysts containing carboxylic-functionalized thiourea ligands are prepared and their activities and recyclability are evaluated in aerobic aqueous Suzuki–Miyaura reactions. A bulky monothiourea–Pd complex, functionalized with four carboxylic groups, shows the best activity and recyclability in the coupling of aryl bromides with arylboronic acids. The catalyst can be reused at least five times without any significant reduction in its catalytic activity. TEM analysis and the confirmed catalytic activity of the observed black precipitate reveal that Pd nanoparticles are formed during the reactions and are stabilized by the carboxylic-functionalized thiourea ligands.

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