Effects of Zinc Binding on the Conformational Distribution of the Amyloid-β Peptide Based on Molecular Dynamics Simulations

2007 ◽  
Vol 111 (49) ◽  
pp. 13814-13821 ◽  
Author(s):  
Wenfei Li ◽  
Jian Zhang ◽  
Yu Su ◽  
Jun Wang ◽  
Meng Qin ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Amyloid Β ◽  
Zinc Binding ◽  
Amyloid Β Peptide ◽  
Dynamics Simulations ◽  
Conformational Distribution

Destabilization of Alzheimer’s Aβ42 protofibrils with acyclovir, carmustine, curcumin, and tetracycline: Insights from molecular dynamics simulations

2021 ◽  
Author(s):  
Ishrat Jahan ◽  
Shahid M Nayeem
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Molecular Dynamics ◽  
Neurodegenerative Diseases ◽  
Molecular Dynamics Simulations ◽  
Amyloid Β ◽  
Neural Tissue ◽  
Amyloid Β Peptide ◽  
Characteristic Symptom ◽  
Dynamics Simulations

One of the most common dementia among neurodegenerative diseases is Alzheimer’s disease (AD). The characteristic symptom of AD is the deposition and aggregation of amyloid-β-peptide in the neural tissue. A...

Sign in / Sign up

Export Citation Format

Share Document