Interactions between Pluronics (F127 and F68) and Bile Salts (NaTDC) in the Aqueous Phase and the Interface of Oil-in-Water Emulsions

Langmuir ◽  
2013 ◽  
Vol 29 (8) ◽  
pp. 2520-2529 ◽  
Author(s):  
Amelia Torcello-Gómez ◽  
Julia Maldonado-Valderrama ◽  
Ana Belén Jódar-Reyes ◽  
Timothy J. Foster
Keyword(s):  
Aqueous Phase ◽  
Bile Salts ◽  
Oil In Water

Nanoemulsions- A better Approach for Anti Diabeticdrugs Delivering

2020 ◽  
Vol 17 ◽  
Author(s):  
V. Manimaran ◽  
Ponnurengam Malliappan Sivakumar ◽  
J. Narayanan ◽  
Shanmugam Parthasarathi ◽  
Pranav Kumar Prabhakar
Keyword(s):  
Aqueous Phase ◽  
Therapeutic Agent ◽  
Antidiabetic Drugs ◽  
Optical Behaviour ◽  
Antimicrobial Drugs ◽  
Drug Degradation ◽  
Oil In Water ◽  
Drug Technology ◽  
Human Use ◽  
Poor Absorption

: Conventional delivery of antidiabetic drugs faces many problems like poor absorption, low bioavailability, and drug degradation. Nanoemulsion is a unique drug technology which is very suitable for the delivery of antidiabetic drugs. In recent years the flaws of delivering anti-hypoglycaemic drugs have been overcome by choosing nanoemulsion drug technology. They are thermodynamically stable and also deliver the therapeutic agent for a longer duration. Generally, Nanoemulsions are made up of either oil-in-water or water-in-oil and size of the droplets is from fifty to thousand nanometer. Surfactants are critical substances which are added in the manufacturing of nanoemulsions. Only the surfactants which are approved for human use can be utilized in the manufacturing of nanoemulsions. Generally, the preparation of emulsions includes mixing of the aqueous phase and organic phase and using surfactant with proper agitation. Nanoemulsions are used for antimicrobial drugs, and they are also used in the prophylaxis of cancer, diabetics. Reduction in the droplet size may cause variation in the elastic and optical behaviour of nanoemulsions.

scholarly journals Pharmaceutical approach to the oral dosage form of macromolecules: Effect of bile salts and oil-in-water emulsions on the intestinal absorption of urogastrone in the rat.

1977 ◽  
Vol 25 (8) ◽  
pp. 1974-1979 ◽  
Author(s):  
RYOHEI HORI ◽  
KATSUHIKO OKUMURA ◽  
KENICHI INUI ◽  
NOBUKUNI NAKAMURA ◽  
AKIMA MIYOSHI ◽  
...  
Keyword(s):  
Intestinal Absorption ◽  
Bile Salts ◽  
Dosage Form ◽  
Oral Dosage ◽  
Oral Dosage Form ◽  
Oil In Water

The effect of Na2SO4 concentration in aqueous phase on the phase inversion temperature of lemon oil in water nano-emulsions

2016 ◽  
Vol 215 ◽  
pp. 454-460 ◽  
Author(s):  
Somaye Mashhadi ◽  
Hamedreza Javadian ◽  
Inderjeet Tyagi ◽  
Shilpi Agarwal ◽  
Vinod Kumar Gupta
Keyword(s):  
Aqueous Phase ◽  
Phase Inversion ◽  
Inversion Temperature ◽  
Oil In Water ◽  
Lemon Oil ◽  
Phase Inversion Temperature

Different stability regimes of oil-in-water emulsions in the presence of bile salts

2010 ◽  
Vol 43 (6) ◽  
pp. 1634-1641 ◽  
Author(s):  
A.B. Jódar-Reyes ◽  
A. Torcello-Gómez ◽  
M. Wulff-Pérez ◽  
M.J. Gálvez-Ruiz ◽  
A. Martín-Rodríguez
Keyword(s):  
Bile Salts ◽  
Oil In Water

scholarly journals Ultrafiltration Method for Measuring Free Preservatives in Aqueous Phase of Oil-in-Water Emulsions

1973 ◽  
Vol 21 (2) ◽  
pp. 316-322 ◽  
Author(s):  
TSUGIO SHIMAMOTO ◽  
YASUAKI OGAWA ◽  
NORIE OHKURA
Keyword(s):  
Aqueous Phase ◽  
Oil In Water

scholarly journals Effect of substituent pattern and molecular weight of cellulose ethers on interactions with different bile salts

2015 ◽  
Vol 6 (3) ◽  
pp. 730-739 ◽  
Author(s):  
Amelia Torcello-Gómez ◽  
Cristina Fernández Fraguas ◽  
Mike J. Ridout ◽  
Nicola C. Woodward ◽  
Peter J. Wilde ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Aqueous Phase ◽  
Bile Salts ◽  
Cellulose Ethers ◽  
Type Pattern

Cellulose ethers interact with bile salts in the aqueous phase. These interactions are affected by the substituent type/pattern of cellulose ethers rather than their molecular weight and by the hydrophobicity of bile salts.

Impact of iron encapsulation within the interior aqueous phase of water-in-oil-in-water emulsions on lipid oxidation

2009 ◽  
Vol 116 (1) ◽  
pp. 271-276 ◽  
Author(s):  
Seung Jun Choi ◽  
Eric Andrew Decker ◽  
David Julian McClements
Keyword(s):  
Lipid Oxidation ◽  
Aqueous Phase ◽  
Oil In Water
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