7-Deoxy-6-epi-castanospermine, a Trihydroxyindolizidine Alkaloid Glycosidase Inhibitor from Castanospermum australe

1990 ◽  
Vol 53 (3) ◽  
pp. 609-614 ◽  
Author(s):  
Russell J. Molyneux ◽  
Joseph E. Tropea ◽  
Alan D. Elbein
Keyword(s):  
Glycosidase Inhibitor ◽  
Castanospermum Australe

Design and synthesis of glycosidase inhibitor 5-amino-1,2,3,4-cyclohexanetetrol derivatives from (−)-vibo-quercitol

2005 ◽  
Vol 13 (13) ◽  
pp. 4306-4314 ◽  
Author(s):  
Seiichiro Ogawa ◽  
Miwako Asada ◽  
Yoriko Ooki ◽  
Midori Mori ◽  
Masayoshi Itoh ◽  
...  
Keyword(s):  
Design And Synthesis ◽  
Glycosidase Inhibitor

Synthesis of Selenium Analogues of the Naturally Occurring Glycosidase Inhibitor Salacinol and Their Evaluation as Glycosidase Inhibitors†

2002 ◽  
Vol 124 (28) ◽  
pp. 8245-8250 ◽  
Author(s):  
Blair D. Johnston ◽  
Ahmad Ghavami ◽  
Morten T. Jensen ◽  
Birte Svensson ◽  
B. Mario Pinto
Keyword(s):  
Glycosidase Inhibitors ◽  
Naturally Occurring ◽  
Glycosidase Inhibitor

Conformational flexibility of sulphur linked saccharides a possible key to their glycosidase inhibitor activity

2008 ◽  
Vol 34 (4) ◽  
pp. 391-402 ◽  
Author(s):  
Gerhard A. Venter ◽  
Richard P. Matthews ◽  
Kevin J. Naidoo
Keyword(s):  
Conformational Flexibility ◽  
Inhibitor Activity ◽  
Glycosidase Inhibitor

A stereoselective transformation of (−)-shikimic acid into (3R,4S,5R,7R)-7-(hydroxymethyl)azepane-3,4,5-triol, a potential glycosidase inhibitor

2015 ◽  
Vol 26 (5-6) ◽  
pp. 320-323 ◽  
Author(s):  
Marcos A. González-Castro ◽  
Darren L. Poole ◽  
Juan C. Estévez ◽  
George W.J. Fleet ◽  
Ramón J. Estévez
Keyword(s):  
Shikimic Acid ◽  
Glycosidase Inhibitor

Flower Mites and Phoresy: the Biology of Hattena Panopla Domrow and Hattena Cometis Domrow (Acari:Mesostigmata:Ameroseiidae)

1996 ◽  
Vol 44 (2) ◽  
pp. 193 ◽  
Author(s):  
OD Seeman
Keyword(s):  
Host Specificity ◽  
Dorsal Surface ◽  
Behavioural Response ◽  
Male And Female ◽  
Larval Stages ◽  
Ephemeral Habitat ◽  
Bruguiera Gymnorhiza ◽  
Flower Age ◽  
Castanospermum Australe ◽  
Flower Mites

Two flower-inhabiting ameroseiid mites exhibited different degrees of host specificity; Hattena panopla occurred only in Bruguiera gymnorhiza, but Hattena cometis occurred in Aegiceras corniculatum, Castanospermum australe, Dendrophthoe vitellina, Erythrina variegara, Aloe sp. and Amyema sp. Both species of mite consumed nectar and probably pollen in the laboratory. Flowers of B. gymnorhiza were short lived and senesced after about 5 days. Most H. panopla inhabited the flower for 1-3 days and relied on birds for transport between flowers, but could move from flower to flower via plant stems and were found on ants visiting dying flowers. H. panopla responded to an aging flower by moving out of the petals onto the calyx. All post-larval stages of H. panopla were phoretic; many immature mites of both species dispersed by climbing onto the dorsal surface of dispersing adult mites. The dispersal of immature mites and the behavioural response of H. panopla to flower age were considered to be adaptations to the mite's ephemeral habitat. Adult female H. cometis and adult male and female H. panopla had sucker-like ambulacra that lacked claws, a probable adaptation for phoresy.

scholarly journals α-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease

2019 ◽  
Vol 10 (40) ◽  
pp. 9233-9243 ◽  
Author(s):  
Marta Artola ◽  
Christinne Hedberg ◽  
Rhianna J. Rowland ◽  
Lluís Raich ◽  
Kassiani Kytidou ◽  
...  
Keyword(s):  
Fabry Disease ◽  
Conformationally Constrained ◽  
New Class ◽  
Glycosidase Inhibitor ◽  
Complex Analog

α-d-Gal-cyclophellitol cyclosulfamidate is a new class of neutral, conformationally-constrained competitive glycosidase inhibitor that stabilizes α-gal A and prevents its degradation both in vitro and in cellulo by mimicry of the Michaelis complex conformation.

Does resource availability govern vertical stratification of small mammals in an Australian lowland tropical rainforest?

2006 ◽  
Vol 33 (7) ◽  
pp. 571 ◽  
Author(s):  
R. Rader ◽  
A. Krockenberger
Keyword(s):  
Resource Availability ◽  
Tropical Rainforest ◽  
Vertical Stratification ◽  
Resource Abundance ◽  
Canopy Trees ◽  
Small Mammal Community ◽  
Castanospermum Australe ◽  
Mammal Community ◽  
Mammal Assemblages ◽  
Access To Food

Mammal assemblages of rainforest communities are commonly vertically stratified. This can be associated with competition for, or access to, resources in the upper canopy layers of the forest. This study investigated the extent of vertical stratification in a small mammal community of a tropical rainforest and whether any structure was related to resource abundance. The mammal community was vertically stratified, with Pogonomys mollipilosus and Cercartetus caudatus found only in the upper canopy layers and Rattus sp., Isoodon macrourus and Antechinus flavipes rubeculus on the ground and in the understorey layer. Melomys cervinipes and Uromys caudimaculatus were found at all four height layers. Total rodent captures were not significantly correlated with the abundance of fruit and flower resources, but arboreal captures of M. cervinipes and P. mollipilosus were correlated with the number of individual canopy trees of four prominent flower- and fruit-yielding species: Syzigium sayeri, Acmena graveolens, Argyrodendron perelatum and Castanospermum australe. We suggest that arboreal behaviour in these rodents serves to provide the advantages of first access to food resources, the availability of abundant resources in the canopy, and, ultimately, reduced competition in the upper strata.

ChemInform Abstract: Novel Synthesis of the Glycosidase Inhibitor Deoxymannojirimycin and of a Synthetic Precursor D-lyxo-Hexos-5-ulose.

ChemInform ◽  
2010 ◽  
Vol 33 (12) ◽  
pp. no-no
Author(s):  
Julie L. O'Brien ◽  
Manuela Tosin ◽  
Paul V. Murphy
Keyword(s):  
Novel Synthesis ◽  
Glycosidase Inhibitor
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