Strategies to improve cell absorption rate: Precise targeting, dual visualization guided, multiple stimulus responsive liposomes for cancer treatment

Author(s):  
Chenyu Liu ◽  
Ning Wang ◽  
Weihe Yao ◽  
Weihong Qiao
Author(s):  
Jie Yu ◽  
Xiaoli Zhang ◽  
Zhichao Pei ◽  
Qi Shuai

Multimodal synergistic therapy has gained increasing attention in cancer treatment to overcome the limitations of monotherapy and achieve high ancicancer efficacy. In this study, a synergistic phototherapy and hypoxic-activated chemotherapy...


2013 ◽  
Vol 8 (3) ◽  
pp. 572-581 ◽  
Author(s):  
Ji Liu ◽  
Yu Feng ◽  
Zhi-Xiong Liu ◽  
Zhi-Chao Yan ◽  
Yan-Mei He ◽  
...  

Author(s):  
Nabilah Abdul Jaffar ◽  
Norlida Buniyamin ◽  
Kasumawati Lias

This paper presents the outcome of a literature review that an overview of various types of antenna and metamaterial applicator performance towards cancerous tissue or cell for non-invasive hyperthermia cancer treatment (NIHCT) procedure. From the review, it shows that when LHM lens integrated with an antenna, focusing capabilities of the antenna towards the cancerous area can be improved. However, current applicators have a poor focusing effect when directed towards the actual tumor area. In conjunction with that, this paper proposes a new design of modified applicator that is microstrip antenna integrated with left-handed metamaterial (LHM) lens. The antenna termed microstrip-LHM (M-LHM) lens antenna is proposed for use in NIHCT. It is expected to improve the focusing capabilities of an antenna which is used to kill the cancerous area and thus improve the hyperthermia cancer treatment procedure success rate. In addition, this paper provides an overview of heating techniques used in hyperthermia to enhance focusing capabilities and a few metamaterial advantages that can improve the focusing effect and reduced the hot-spots. Specific Absorption Rate (SAR) will be investigated to evaluate the focusing abilities of the proposed applicator using the SEMCAD X Solver.


2015 ◽  
Vol 119 (28) ◽  
pp. 16349-16357 ◽  
Author(s):  
Yanjun Gong ◽  
Tiliu Jiao ◽  
Qiongzheng Hu ◽  
Ni Cheng ◽  
Wenwen Xu ◽  
...  

2014 ◽  
Vol 21 (3) ◽  
pp. 1064-1072 ◽  
Author(s):  
Wangen Miao ◽  
Long Qin ◽  
Dong Yang ◽  
Xue Jin ◽  
Minghua Liu

2021 ◽  
pp. 134410
Author(s):  
Xiaolin Nie ◽  
Shuanglin Wu ◽  
Pengfei Lv ◽  
Huizhen Ke ◽  
Fenglin Huang ◽  
...  

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Qiang Shi ◽  
Hao Liu ◽  
Deding Tang ◽  
Yuhui Li ◽  
XiuJun Li ◽  
...  

Abstract The increasingly intimate bond connecting soft actuation devices and emerging biomedical applications is triggering the development of novel materials with superb biocompatibility and a sensitive actuation capability that can reliably function as bio-use-oriented actuators in a human-friendly manner. Stimulus-responsive hydrogels are biocompatible with human tissues/organs, have sufficient water content, are similar to extracellular matrices in structure and chemophysical properties, and are responsive to external environmental stimuli, and these materials have recently attracted massive research interest for fabricating bioactuators. The great potential of employing such hydrogels that respond to various stimuli (e.g., pH, temperature, light, electricity, and magnetic fields) for actuation purposes has been revealed by their performances in real-time biosensing systems, targeted drug delivery, artificial muscle reconstruction, and cell microenvironment engineering. In this review, the material selection of hydrogels with multiple stimulus-responsive mechanisms for actuator fabrication is first introduced, followed by a detailed introduction to and discussion of the most recent progress in emerging biomedical applications of hydrogel-based bioactuators. Final conclusions, existing challenges, and upcoming development prospects are noted in light of the status quo of bioactuators based on stimulus-responsive hydrogels.


2017 ◽  
Vol 12 (22) ◽  
pp. 2962-2966 ◽  
Author(s):  
Fanfan Meng ◽  
Chengfen Xing ◽  
Hongbo Yuan ◽  
Yibing Fan ◽  
Ran Chai ◽  
...  

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