Early life factors related to clinical manifestations of atopic disease but not to skin-prick test positivity in young children

2002 ◽  
Vol 13 (2) ◽  
pp. 105-112 ◽  
Author(s):  
Maria-Antonietta Stazi ◽  
Francesca Sampogna ◽  
GIuseppe Montagano ◽  
Michele E. Grandolfo ◽  
Marie-France Couilliot ◽  
...  
Keyword(s):  
Young Children ◽  
Skin Prick Test ◽  
Early Life ◽  
Clinical Manifestations ◽  
Atopic Disease ◽  
Prick Test ◽  
Early Life Factors

Disagreement between skin prick test and specific IgE in young children

Allergy ◽  
2014 ◽  
Vol 70 (1) ◽  
pp. 41-48 ◽  
Author(s):  
A.-M. M. Schoos ◽  
B. L. K. Chawes ◽  
N. V. Følsgaard ◽  
N. Samandari ◽  
K. Bønnelykke ◽  
...  
Keyword(s):  
Young Children ◽  
Skin Prick Test ◽  
Specific Ige ◽  
Prick Test

scholarly journals Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

2013 ◽  
Vol 131 (5) ◽  
pp. 301-308 ◽  
Author(s):  
Raquel Prudente de Carvalho Baldacara ◽  
Maria de Fatima Marcelos Fernandes ◽  
Leonardo Baldacara ◽  
Wilson Tartuce Aun ◽  
Joao Ferreira de Mello ◽  
...  
Keyword(s):  
Family History ◽  
Skin Prick Test ◽  
Cesarean Delivery ◽  
Atopic Disease ◽  
Dermatophagoides Pteronyssinus ◽  
Outpatient Clinics ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Prick Test ◽  
History Of

CONTEXT AND OBJECTIVE: Knowledge of the profile of allergen sensitization among children is important for planning preventive measures. The objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of Palmas. DESIGN AND SETTING: Cross-sectional study at outpatient clinics in Palmas, Tocantins, Brazil. METHODS: Ninety-four patients aged 1-15 years who were attending two pediatric outpatient clinics were selected between September and November 2008. All of the subjects underwent clinical interviews and skin prick tests. RESULTS: A positive skin prick test was observed in 76.6% of the participants (72.3% for inhalants and 28.9% for food allergens). The most frequent allergens were Dermatophagoides pteronyssinus (34%), cat epithelium (28.7%), dog epithelium (21.3%), Dermatophagoides farinae (19.1%), Blomia tropicalis (18.1%), cow's milk (9.6%) and grasses (9.6%). A positive skin prick test correlated with a history of atopic disease (odds ratio, OR = 5.833; P = 0.002), a family history of atopic disease (OR = 8.400; P < 0.001), maternal asthma (OR = 8.077; P = 0.048), pet exposure (OR = 3.600; P = 0.012) and cesarean delivery (OR = 3.367; P = 0.019). CONCLUSION: Dermatophagoides pteronyssinus was the most frequent aeroallergen and cow’s milk was the most prevalent food allergen. There was a positive correlation between a positive skin prick test and several factors, such as a family history of atopic disease, maternal asthma, pet exposure and cesarean delivery.

scholarly journals GENETIC AND ENVIRONMENTAL FACTORS AS STRONG DETERMINANTS OF ATOPIC ALLERGIC DISEASE CLINICAL MANIFESTATIONS IN SURABAYA'S SCHOOL CHILDREN

2017 ◽  
Vol 53 (3) ◽  
pp. 220
Author(s):  
Gatot Soegiarto ◽  
Luki Agustina Damayanti ◽  
Chairul Effendi
Keyword(s):  
Allergic Rhinitis ◽  
High Schools ◽  
Environmental Factors ◽  
Skin Prick Test ◽  
School Children ◽  
Genetic Factors ◽  
Clinical Manifestations ◽  
Positive Skin Prick Test ◽  
Prick Test ◽  
Genetic And Environmental Factors

This case-control study was conducted to assess the relative role of genetic and environmental factors in determining the clinical manifestations of atopy allergy disease in school children, which is part of a large study of the prevalence of allergic diseases in school children in Surabaya. Using a simple multi-stage random sampling, 348 children from 5 elementary schools, 4 junior high schools, and 4 senior high schools in Surabaya were involved in the study. The subjects of the study along with her parents were guided to fill out the modified ISAAC questionnaire and underwent physical examination and skin prick test using 27 common allergen types found in the environment. For the analysis, 110 school children were randomly selected from the parent sample and included in the case group of 55 people (positive skin prick test against > 1 type of allergen), and the control group of 55 people (negative skin prick test). All genetic and environmental factors data were collected and analyzed. Most of the subjects had clinical manifestations of allergic rhinitis (66.36%), asthma (21.82%), food allergies (10.9%), and atopic dermatitis (6.36%). Complete models for multiple logistic regression analysis can only be performed for overall atopic disease and allergic rhinitis disease. The first birth order and exposure to home dust mites were the most significant clinical manifestations of atopy disease (OR 4.548, 95% CI: 1.813-11.410, p=0.01). Atopy status of the father was the only significant determinant factor for the manifestation of allergic rhinitis in the study subjects (OR 3.929; 95% CI: 1.143-13.052, p=0.03). Both genetic and environmental factors interacted and determined clinical manifestations of atopy allergy disease in school pupils. The father's genetic factors were more dominant than maternal genetic factors in determining the clinical manifestations of allergic rhinitis in offspring.

Clinical Manifestations of Allergic Rhinitis by Age and Gender: A 12-Year Single-Center Study

2020 ◽  
Vol 129 (9) ◽  
pp. 910-917
Author(s):  
Seung-No Hong ◽  
Jun Yeon Won ◽  
Eui-Cheol Nam ◽  
Tae Su Kim ◽  
Yoon-Jong Ryu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Clinical Characteristics ◽  
Clinical Manifestations ◽  
Nasal Symptom ◽  
House Dust Mites ◽  
Allergen Sensitization ◽  
Prick Test ◽  
Sensitization Rate ◽  
Age And Sex

Objectives: Currently, epidemiological data on allergic rhinitis collected through the skin prick test are scarce. Moreover, the relationship of age and sex to allergic rhinitis is not comprehensively understood. This study aimed to characterize allergic rhinitis and the associated clinical manifestations by age and sex. Methods: We retrospectively investigated data from 2883 patients who visited a single university hospital for rhinitis symptoms between January 2003 and December 2014. Of these 2883 patients, 1964 who underwent a skin prick test with 11 standardized allergen extracts and completed a nasal symptom questionnaire were enrolled. The clinical characteristics of allergen sensitization and nasal symptoms were analyzed by sex and age distribution. Results: The prevalence of allergen sensitization progressively decreased with age after peaking at between 20 and 29 years. The sensitization rate was higher in males than in females ( P = .046). The sensitization rate to house dust mites decreased with age, while sensitization to mugwort and ragweed increased. Six allergens ( Dermatophagoides pteronyssinus, Dermatophagoides farinae, mugwort, trees, ragweed, and cats) were sufficient to identify >96% of patients with allergen sensitization. Nasal obstruction tended to decrease with age and was more prevalent in males ( P = .002) than in females, while rhinorrhea ( P = .007) and itching ( P = .013) were more prevalent in females. Total nasal symptom scores did not differ by sex. Conclusions: The clinical characteristics of allergic rhinitis, including allergen-sensitization patterns and related symptoms, varied by age and sex. Six common allergens could be sufficient to generate a cost-effective tool to identify allergic rhinitis.

scholarly journals Distribution of atopic conditions among attendants to specialized allergy center/ Kirkuk/ Iraqi

2020 ◽  
Vol 3 (2) ◽  
pp. 139-153
Author(s):  
Chinar Kanbar ◽  
Abdulameer Samad ◽  
Ali Galleb
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Environmental Factors ◽  
Skin Prick Test ◽  
House Dust ◽  
House Dust Mite ◽  
Atopic Disease ◽  
Atopic Diseases ◽  
Prick Test ◽  
Dust Mite

Atopy is a syndrome characterized by genetic tendency to develop allergic diseases, such as asthma, allergic rhinitis and atopic dermatitis. The risk factors of atopic diseases can be placed in two categories, namely host and environmental factors. The host factors of allergy include genetics, race, gender, age… etc. The environmental factors include exposure to environmental pollution and allergens. To define the distribution of atopic conditions (asthma, allergic rhinitis and atopic dermatitis) according to age, residence and available skin prick test. This cross-sectional study included (100) patients, representing research sample. It was conducted in specialized allergy center in Kirkuk city during the period from first January .2016 to the end of December 2016 All patients included in this study were referred from primary health centers, complaining from signs and symptoms of atopic diseases. Depending on medical history and clinical examinations, the sample was classified into (3) groups (asthma, allergic rhinitis and atopic dermatitis). Skin prick test was used to identify patients allergy to house dust mite and pollen. Regarding the distribution of samples according to residence, most patients (about 91%) were from urban areas compared with (9%) of them were from rural areas. Also, it was found that the frequency of atopic diseases decreases by age advancement. The frequency distribution of asthma, allergic rhinitis and atopic dermatitis was 49%, 26% and 25%, respectively. The skin test data revealed the frequency of 2 aeroallergen mite and pollen in all patients under study. .Hence, 65% were sensitive to house dust mite, 26% to pollen and 9% to both mite and pollen In conclusion this study confirmed that most patients complaining from atopic disease were from urban area. Also, the frequency of atopic diseases decreased by age advancement. The most common atopic disease was asthma followed by allergic rhinitis and atopic dermatitis. Most patients were sensitive to house dust mite.

scholarly journals The association between fever in the first year of life and atopy in children with or without family history of atopic disease

2007 ◽  
Vol 47 (2) ◽  
pp. 65
Author(s):  
Susy P. Wihadi ◽  
Budi Setiabudiawan ◽  
Cissy B. Kartasasmita
Keyword(s):  
Family History ◽  
Skin Prick Test ◽  
Clinical Epidemiology ◽  
Atopic Disease ◽  
Total Serum ◽  
First Year ◽  
Prick Test ◽  
History Of ◽  
First Year Of Life

Background The role of repeated infection in early life in thedevelopment of childhood atopy is still controversy. Fever in thefirst year of life which is frequently associated with infections mightdecrease atopy.Objective The aim of this study was to investigate the associationbetween fever in the first year of life and atopy in children.Methods This was an observational clinical epidemiology studyperformed at Puskesmas Garuda, Padasuka, and Babakan Sari,Bandung, from January to March 2006. From 749 children, werandomly chose 150 subjects each from group with and withoutfamily history of atopic disease. Skin prick test and measurementof total serum immunoglobulin (Ig) E were performed on eachchildren. Atopy was defined as the skin prick test result waspositive to >1 allergen. The number of fever episodes in the firstyear of life was based on parents report. The relationship betweenfever and atopy was analyzed using Mantel Haenszel.Results From 284 subjects, atopy was found in 28.2% of children,of which 32.4% with and 23.9% without a family history of atopicdisease. Generally there was no significant association betweenfever and atopy. There was only decreased odds ratio withincreased fever episodes and trend analysis showed this decreasewas significant (P=0.01). The significant association betweenfever and atopy were found only in group without family historyof atopic disease (P=0.03, OR=0.43, CI 95% 0.18;1.01).Conclusion There is a relationship between fever and atopy inchildren without family history of atopic disease.

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