Patch testing with the European standard series and Compositae extracts in patients with airborne contact dermatitis

Background: Moisturizers are cosmetic products used routinely to manage various skin conditions. Even though moisturizers are often thought to have minimal or no adverse reactions, allergic contact dermatitis (ACD) to these products can develop in some cases. Methods: We studied ingredients included in 3 of the most commonly used moisturizer brands, identified their presence in standard patch testing series, and evaluated their allergenic potential, categorizing the allergens as frequent or infrequent. The standard patch testing series used as reference were the Thin-layer Rapid Use Epicutaneous patch test (T.R.U.E. test), the North American Contact Dermatitis Group (NACDG) screening standard series, and the American Contact Dermatitis Society (ACDS) core allergen series. Results: Aveeno, Cetaphil, and Cerave products had a total of 12, 14, and 9 potential allergens, respectively, the majority of which were infrequent and not included in standard patch testing series. Conclusion: Being aware of the allergenic potential of commonly used moisturizers may help healthcare providers when evaluating patients with ACD. Further testing is recommended in a targeted manner when suspecting ACD with negative standard patch testing series or when ACD is refractory to treatment.

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Patch testing with the European standard series in Shanghai

Contact Dermatitis ◽

10.1111/j.1600-0536.1994.tb00701.x ◽

1994 ◽

Vol 30 (3) ◽

pp. 173-174 ◽

Cited By ~ 11

Author(s):

Xue Min Wang ◽

Yin Fen Lin ◽

Xia Feng Cheng ◽

Yan Pin Zhang ◽

Mei Li Ye

Keyword(s):

Patch Testing ◽

Standard Series ◽

European Standard

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Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

Dermatology Research and Practice ◽

10.1155/2014/695387 ◽

2014 ◽

Vol 2014 ◽

pp. 1-5 ◽

Cited By ~ 5

Author(s):

Pramod Kumar ◽

Rekha Paulose

Keyword(s):

Contact Dermatitis ◽

Allergic Contact Dermatitis ◽

Patch Testing ◽

Age Group ◽

Cosmetic Products ◽

Standard Series ◽

Hair Dyes ◽

Common Allergen ◽

Cosmetic Product ◽

Allergic Contact

Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the actual allergens which are chemical mixtures of various ingredients.Objectives. The aims of this study are to perform patch testing in suspected ACD to cosmetics and to identify the most common allergen and cosmetic product causing dermatitis.Methods. Fifty patients with suspected ACD to cosmetics were patch-tested with 38 antigens of the Indian Cosmetic Series and 12 antigens of the Indian Standard Series.Results. The majority (58%) of patients belonged to the 21–40 years age group. The presence of ACD to cosmetics was confirmed in 38 (76%) patients. Face creams (20%), hair dyes (14%), and soaps (12%) were the most commonly implicated. The most common allergens identified were gallate mix (40%), cetrimide (28%), and thiomersal (20%). Out of a total of 2531 patches applied, positive reactions were obtained in 3.75%.Conclusion. Incidence of ACD to cosmetics was greater in females. Face creams and hair dyes were the most common cosmetic products implicated. The principal allergens were gallate mix, cetrimide, and thiomersal.

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Relevance of patch testing and its correlation with clinical patterns of contact dermatitis of hand

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20192072 ◽

2019 ◽

Vol 5 (3) ◽

pp. 498

Author(s):

Devaprabha Sendurpandian ◽

M. R. Subashini

Keyword(s):

Contact Dermatitis ◽

Patch Testing ◽

Hand Eczema ◽

Standard Series ◽

Morphological Pattern ◽

Female Ratio ◽

Patch Tests ◽

International Contact ◽

Male Female Ratio ◽

Clinical Patterns

Background: Contact dermatitis of hand is a common dermatoses with different aetiological conditions and different morphologies. The aim of our study is to identify the clinical patterns, causative allergens and the relevance of patch testing for contact dermatitis of hand.Methods: A total of 74 patients with hand eczema were included in our study after getting informed and written consent to do patch tests during December 2016 to May 2017 in our dermatology OPD. Patch test was done by using Indian standard series battery and the readings were taken at 48 hrs and 72 hrs. The results were interpreted according to International Contact Dermatitis Research Group (ICDRG) criteria.Results: The incidence of hand eczema was 3.2 percent with male: female ratio of 1.55:1. The most common age group affected was 31-40 years. The most common morphological pattern observed in our study was fissured pattern (43%) followed by unspecified pattern (23%), hyperkeratotic (12%), lichenoid (10%), pompholyx (4%), fingertip eczema (1%), ring pattern (1%) and mixed morphology (6%). In our study, current relevance of 79% (31 allergens), doubtful relevance of 15% (6 allergens), and old relevance of 3% (one allergen) was noted. Cross sensitization was observed with one allergen (3%).Conclusions: Patch testing is a very useful scientific diagnostic tool that unravels the cause of contact dermatitis of hand. Avoidance of the substances responsible for allergy can be advised to the patient.

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ETIOLOGY OF CONTACT DERMATITIS ON FACE IN INDIAN PATIENTS

10.36106/6010033 ◽

2021 ◽

pp. 34-35

Author(s):

Molisha Bhandari ◽

Sushruta Kathuria ◽

Niti Khunger

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Patch Testing ◽

Standard Series ◽

Over The Counter ◽

The Past ◽

Indian Patients ◽

The Mean ◽

Facial Dermatitis ◽

Topical Medications

Introduction: Facial contact dermatitis has exponentially increased in the past decade because of the freely available over the counter topical medications and the innumerable cosmetics. Patch testing is still the gold standard for diagnosis. Aims and Objectives: To elicit the patterns and specic allergens causing facial dermatitis on face in Indian patients. 50 patients of predominantly facial dermatitis with Materials and methods: suspected contact dermatitis (CD) were taken up for patch testing. The patients were tested with the Indian standard series (ISS) and Indian cosmetic series and the results were read at 48 and 96 hours. Repeated open application test (ROAT) was performed with the suspected allergens in 33 patients, and the results were read on Days 2, 4, and 7 using the Johansen's Modied scale. Results: The mean age of the patients was 48.3 years with M: F ratio of 3:7. The mean duration of the complaints was 20 months, while the mean duration of exposure to the implicated allergen was 10.6 years. Patch test with ISS and cosmetic series were positive in 34% of people with 4-Phenylenediamine base PPD (1%) being the most common allergen in 14 patients. ROAT was positive in 18 patients, out of which 78% were patch test negative. Patch test has stood the test of Discussion: time as an invaluable diagnostic aid in patients with dermatitis. Sindoor dermatitis is a commonly encountered ACD in our clinics but the implicated allergens are not a part of ISS or cosmetic series. In our study, ROAT was positive in 8 patients of sindoor dermatitis who were patch test negative. Thus, ROAT should also be ideally be performed in these patients.

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