ETIOLOGY OF CONTACT DERMATITIS ON FACE IN INDIAN PATIENTS

2021 ◽  
pp. 34-35
Author(s):  
Molisha Bhandari ◽  
Sushruta Kathuria ◽  
Niti Khunger

Introduction: Facial contact dermatitis has exponentially increased in the past decade because of the freely available over the counter topical medications and the innumerable cosmetics. Patch testing is still the gold standard for diagnosis. Aims and Objectives: To elicit the patterns and specic allergens causing facial dermatitis on face in Indian patients. 50 patients of predominantly facial dermatitis with Materials and methods: suspected contact dermatitis (CD) were taken up for patch testing. The patients were tested with the Indian standard series (ISS) and Indian cosmetic series and the results were read at 48 and 96 hours. Repeated open application test (ROAT) was performed with the suspected allergens in 33 patients, and the results were read on Days 2, 4, and 7 using the Johansen's Modied scale. Results: The mean age of the patients was 48.3 years with M: F ratio of 3:7. The mean duration of the complaints was 20 months, while the mean duration of exposure to the implicated allergen was 10.6 years. Patch test with ISS and cosmetic series were positive in 34% of people with 4-Phenylenediamine base PPD (1%) being the most common allergen in 14 patients. ROAT was positive in 18 patients, out of which 78% were patch test negative. Patch test has stood the test of Discussion: time as an invaluable diagnostic aid in patients with dermatitis. Sindoor dermatitis is a commonly encountered ACD in our clinics but the implicated allergens are not a part of ISS or cosmetic series. In our study, ROAT was positive in 8 patients of sindoor dermatitis who were patch test negative. Thus, ROAT should also be ideally be performed in these patients.

2020 ◽  
Vol 24 (4) ◽  
pp. 350-359
Author(s):  
Stephanie R. Cohen ◽  
Jesús A. Cárdenas-de la Garza ◽  
Paige Dekker ◽  
Wasim Haidari ◽  
Sarah S. Chisolm ◽  
...  

Background: Moisturizers are cosmetic products used routinely to manage various skin conditions. Even though moisturizers are often thought to have minimal or no adverse reactions, allergic contact dermatitis (ACD) to these products can develop in some cases. Methods: We studied ingredients included in 3 of the most commonly used moisturizer brands, identified their presence in standard patch testing series, and evaluated their allergenic potential, categorizing the allergens as frequent or infrequent. The standard patch testing series used as reference were the Thin-layer Rapid Use Epicutaneous patch test (T.R.U.E. test), the North American Contact Dermatitis Group (NACDG) screening standard series, and the American Contact Dermatitis Society (ACDS) core allergen series. Results: Aveeno, Cetaphil, and Cerave products had a total of 12, 14, and 9 potential allergens, respectively, the majority of which were infrequent and not included in standard patch testing series. Conclusion: Being aware of the allergenic potential of commonly used moisturizers may help healthcare providers when evaluating patients with ACD. Further testing is recommended in a targeted manner when suspecting ACD with negative standard patch testing series or when ACD is refractory to treatment.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Pramod Kumar ◽  
Rekha Paulose

Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the actual allergens which are chemical mixtures of various ingredients.Objectives. The aims of this study are to perform patch testing in suspected ACD to cosmetics and to identify the most common allergen and cosmetic product causing dermatitis.Methods. Fifty patients with suspected ACD to cosmetics were patch-tested with 38 antigens of the Indian Cosmetic Series and 12 antigens of the Indian Standard Series.Results. The majority (58%) of patients belonged to the 21–40 years age group. The presence of ACD to cosmetics was confirmed in 38 (76%) patients. Face creams (20%), hair dyes (14%), and soaps (12%) were the most commonly implicated. The most common allergens identified were gallate mix (40%), cetrimide (28%), and thiomersal (20%). Out of a total of 2531 patches applied, positive reactions were obtained in 3.75%.Conclusion. Incidence of ACD to cosmetics was greater in females. Face creams and hair dyes were the most common cosmetic products implicated. The principal allergens were gallate mix, cetrimide, and thiomersal.


Author(s):  
Devaprabha Sendurpandian ◽  
M. R. Subashini

<p class="abstract"><strong>Background:</strong> Contact dermatitis of hand is a common dermatoses with different aetiological conditions and different morphologies. The aim of our study is to identify the clinical patterns, causative allergens and the relevance of patch testing for contact dermatitis of hand.</p><p class="abstract"><strong>Methods:</strong> A total of 74 patients with hand eczema were included in our study after getting informed and written consent to do patch tests during December 2016 to May 2017 in our dermatology OPD. Patch test was done by using Indian standard series battery and the readings were taken at 48 hrs and 72 hrs. The results were interpreted according to International Contact Dermatitis Research Group (ICDRG) criteria.<strong></strong></p><p class="abstract"><strong>Results:</strong> The incidence of hand eczema was 3.2 percent with male: female ratio of 1.55:1. The most common age group affected was 31-40 years. The most common morphological pattern observed in our study was fissured pattern (43%) followed by unspecified pattern (23%), hyperkeratotic (12%), lichenoid (10%), pompholyx (4%), fingertip eczema (1%), ring pattern (1%) and mixed morphology (6%). In our study, current relevance of 79% (31 allergens), doubtful relevance of 15% (6 allergens), and old relevance of 3% (one allergen) was noted. Cross sensitization was observed with one allergen (3%).</p><p class="abstract"><strong>Conclusions:</strong> Patch testing is a very useful scientific diagnostic tool that unravels the cause of contact dermatitis of hand. Avoidance of the substances responsible for allergy can be advised to the patient.</p>


2015 ◽  
Vol 19 (1) ◽  
pp. 77-80 ◽  
Author(s):  
Kathleen Fraser ◽  
Melanie Pratt

Background: In allergic contact dermatitis (ACD), polysensitization consists of positive patch test reactions to three or more unrelated allergens. Objective: The purpose of this case report is to document a 27-year-old female with recurrent lip dermatitis, polysensitization, and reactions to a number of clinically relevant exposures. Methods: Patch testing results revealed positive reactions to tixocortol-21-pivalate (3+), lanolin (3+), neomycin (3+), nickel (1+), hydroxyethyl methylacrylate (3+), bacitracin (3+), and abitol (3+). Results: The patient had seven positive reactions, meeting the criteria for polysensitization. Of known clinical relevance, the patient had applied lanolin-containing lip balms and hydrocortisone- and bacitracin-containing products to the lips, all of which she was strongly reactive to on patch testing. Conclusion: Polysensitization occurs when three or more unrelated allergens are positive on patch testing. This case highlights the importance of considering polysensitization in ACD as numerous allergens that were positive on patch testing were clinically relevant.


2016 ◽  
Vol 14 (1) ◽  
pp. 14-17
Author(s):  
S. Bhattarai ◽  
A. Rijal ◽  
S. Agrawal

Introduction: Allergic contact dermatitis in Nepal is not an uncommon disorder. Patch testing is a well established method of diagnosing allergic contact dermatitis. Patients with contact dermatitis are well known to have impaired quality of life which often leads to frequent dermatological consultations.Objective: Lack of data from Nepal has prompted us to undertake this study with the aims to know the frequency of allergic contact dermatitis and the commonest contact allergens among the patients with Hand eczema attending the out-patient department of dermatology, B.P. Koirala Institute of Health Sciences and Kathmandu Medical College Teaching Hospital.Material and Methods: A total of 256 patients were included in the study. Out of them 195 with hand eczema agreed to participate and undergo patch testing. The antigens used included the Indian standard series of patch test allergens approved by Contact and Occupational Dermatoses Forum of India.Results: Hundred and ten cases (56.4%) were patch test positive (PTP) at 48 as well as 96 hours to at least one allergen. PTP was seen more commonly in females. The most common allergen in females was nickel sulphate followed by cobalt chloride, gentamicin and mercapto mix while males were positive to potassium dichromate, followed by epoxy resin, fragrance mix and nickel sulphate.Conclusion: Patch testing has proved a useful tool for the detection of allergic contact dermatitis and for identification of contact allergens. When positive reactions correlate with environmental exposure the test usually assists the physician in establishing the cause of dermatitis, hence treating the patients and improving their quality of life.Nepal Journal of Dermatology, Venereology & Leprology, Vol.14(1) 2016, pp.14-17


2021 ◽  
Vol 0 ◽  
pp. 1-5
Author(s):  
Thacharamban Mansoorali ◽  
Abdulsalam Sarin

Objectives: The objective of the study was to identify the allergens showing positive patch test reaction (using Indian standard battery of allergens) in cement workers with clinically diagnosed allergic contact dermatitis (CD) to cement attending a tertiary referral center. Materials and Methods: We included cement workers with clinically diagnosed allergic CD to cement who attended the dermatology outpatient clinic of our tertiary referral center from January 2013 to December 2013. We did patch testing in all the cases ( after subsidence of active dermatitis) with Indian standard battery of patch test allergens and documented the allergens that showed a positive reaction. Results: Forty-seven (94%) of the 50 study participants showed a positive reaction to one or more of the allergens. The most common allergen that showed a positive reaction was potassium dichromate (43/50, 86%). Twenty-five patients (50%) showed positive reactions to more than 1 allergen. Four patients (8%) showed positive reactions only to allergens that were not seen in cement. Limitations: Small sample size and lack of information on clinical response of dermatitis to avoidance of identified allergen were the major limitations. Conclusion: Twenty-five (50%) patients showing positive reactions to more than 1 allergen tested and 4 (8%) showing positive patch test reaction to none of the allergens in cement (but to other allergens) highlight the role of patch testing in identifying the probable allergens in patients with clinically diagnosed allergic CD to cement.


2009 ◽  
Vol 13 (4) ◽  
pp. 226-229 ◽  
Author(s):  
Elliott Brodbaker ◽  
Melanie Pratt

Purpose: To report two cases of aluminum contact dermatitis caused by different sources. Methods: Two patients were patch-tested for suspected contact sensitivities. Results: The results of patch testing revealed aluminum contact dermatitis reactions in both patients. Conclusion: Aluminum contact dermatitis is a rare finding with many possible etiologies. One should consider aluminum sensitivity when all patch test sites are positive when using aluminum Finn Chambers.


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