Recent advances in the understanding of the repeated bout effect: the protective effect against muscle damage from a single bout of eccentric exercise

2003 ◽  
Vol 13 (2) ◽  
pp. 88-97 ◽  
Author(s):  
Malachy P. McHugh
Keyword(s):  
Protective Effect ◽  
Muscle Damage ◽  
Eccentric Exercise ◽  
Repeated Bout Effect ◽  
Recent Advances ◽  
Single Bout ◽  
Repeated Bout

Power loss is attenuated following a second bout of high intensity eccentric contractions due to the repeated bout effect’s protection of rate of torque and velocity development

2020 ◽  
Author(s):  
Avery Hinks ◽  
Adam Hess ◽  
Mathew I. B. Debenham ◽  
Jackey Chen ◽  
Nicole Mazara ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
High Intensity ◽  
Power Loss ◽  
Peak Power ◽  
Eccentric Contractions ◽  
Peak Power Output ◽  
Repeated Bout Effect ◽  
Maximum Voluntary Isometric Contraction ◽  
Repeated Bout

High intensity unaccustomed eccentric contractions result in weakness and power loss due to fatigue and muscle damage. Through the repeated bout effect (RBE), adaptations occur, then damage and weakness are attenuated following a subsequent bout. However, it is unclear whether the RBE protects peak power output. We investigated the influence of the RBE on power production and estimated fatigue- and damage-induced neuromuscular impairments following repeated high-intensity eccentric contractions. Twelve healthy adult males performed 5 sets of 30 maximal eccentric elbow flexions and repeated an identical bout 4 weeks later. Recovery was tracked over 7 days following both bouts. Reduced maximum voluntary isometric contraction torque, and increased serum creatine kinase and self-reported soreness indirectly inferred muscle damage. Peak isotonic power, time-dependent measures—rate of velocity development (RVD) and rate of torque development (RTD)—and several electrophysiological indices of neuromuscular function were assessed. The RBE protected peak power, with a protective index of 66% 24 hours after the second eccentric exercise bout. The protection of power also related to preserved RVD (R2=0.61, P<0.01) and RTD (R2=0.39, P<0.01). Furthermore, the RBE’s protection against muscle damage permitted the estimation of fatigue-associated neuromuscular performance decrements following eccentric exercise. Novelty Bullets • The repeated bout effect protects peak isotonic power. • Protection of peak power relates to preserved rates of torque and velocity development, but more so rate of velocity development. • The repeated bout effect has little influence on indices of neuromuscular fatigue.

Effect of eccentric contraction velocity on muscle damage in repeated bouts of elbow flexor exercise

2010 ◽  
Vol 35 (4) ◽  
pp. 534-540 ◽  
Author(s):  
Renato Barroso ◽  
Hamilton Roschel ◽  
Carlos Ugrinowitsch ◽  
Rubens Araújo ◽  
Kazunori Nosaka ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Mixed Model ◽  
Creatine Kinase Activity ◽  
Repeated Bout Effect ◽  
Full Extension ◽  
Maximal Voluntary Isometric Contraction ◽  
Mixed Model Analysis ◽  
Contraction Velocity ◽  
Repeated Bout

Eccentric exercise induces muscle damage, but controversy exists concerning the effect of contraction velocity on the magnitude of muscle damage, and little is known about the effect of contraction velocity on the repeated-bout effect. This study examined slow (60°·s–1) and fast (180°·s–1) velocity eccentric exercises for changes in indirect markers of muscle damage following 3 exercise bouts that were performed every 2 weeks. Fifteen young men were divided into 2 groups based on the velocity of eccentric exercise: 7 in the Ecc60 (60°·s–1) group, and 8 in the Ecc180 (180°·s–1) group. The exercise consisted of 30 maximal eccentric contractions of the elbow flexors at each velocity, in which the elbow joint was forcibly extended from 60° to 180° (full extension) on an isokinetic dynamometer. Changes in maximal voluntary isometric contraction strength, range of motion, muscle soreness, and plasma creatine kinase activity before and for 4 days after the exercise were compared in the 2 groups using a mixed-model analysis (group × bout × time). No significant differences between groups were evident for changes in any variables following exercise bouts; however, the changes were significantly smaller (p < 0.05) after the second and third bouts than after the first bout. These results indicate that the contraction velocity does not influence muscle damage or the repeated-bout effect.

scholarly journals Muscle damage and inflammation after eccentric exercise: can the repeated bout effect be removed?

2015 ◽  
Vol 3 (12) ◽  
pp. e12648 ◽  
Author(s):  
Nikos V. Margaritelis ◽  
Anastasios A. Theodorou ◽  
Vasilios Baltzopoulos ◽  
Constantinos N. Maganaris ◽  
Vassilis Paschalis ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Repeated Bout Effect ◽  
Repeated Bout

scholarly journals Human alpha-actinin-3 genotype association with exercise-induced muscle damage and the repeated-bout effect

2012 ◽  
Vol 37 (6) ◽  
pp. 1038-1046 ◽  
Author(s):  
Tomas Venckunas ◽  
Albertas Skurvydas ◽  
Marius Brazaitis ◽  
Sigitas Kamandulis ◽  
Audrius Snieckus ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Knee Extension ◽  
Repeated Bout Effect ◽  
Drop Jumps ◽  
Jumping Exercise ◽  
Exercise Induced ◽  
Torque Values ◽  
The Impact ◽  
Repeated Bout

Alpha-actinin-3 (ACTN3) is an integral part of the Z line of the sarcomere. The ACTN3 R577X (rs1815739) polymorphism determines the presence or absence of functional ACTN3, which may influence the extent of exercise-induced muscle damage. This study aimed to compare the impact of, and recovery from, muscle-damaging eccentric exercise on subjects with or without functional ACTN3. Seventeen young men (20–33 years old), homozygous for the R (n = 9) or X (n = 8) alleles, performed two bouts of stretch–shortening exercise (50 drop jumps) two weeks apart. Muscle soreness, plasma creatine kinase (CK) activity, jump height, maximal voluntary isometric torque (MVC), peak concentric isokinetic torque (IT), and electrically stimulated knee extension torques at 20 and 100 Hz were measured at baseline and at a number of time points up to 14 days after each bout. There were no significant baseline differences between the groups. However, significant time point × genotype interactions were observed for MVC (p = 0.021) and IT (p = 0.011) for the immediate effect of eccentric exercise in bout 1. The RR group showed greater voluntary force decrements (RR vs. XX: MVC, –33.3% vs. –24.5%; IT, –35.9% vs. –23.2%) and slower recovery. A repeated-bout effect was clearly observed, but there were no differences by genotype group. The ACTN3 genotype modulates the response of muscle function to plyometric jumping exercise, although the differences are modest. The ACTN3 genotype does not influence the clearly observed repeated-bout effect; however, XX homozygotes recover baseline voluntary torque values faster and thus may be able to undertake more frequent training sesssions.

Flexibility training and the repeated-bout effect: priming interventions prior to eccentric training of the knee flexors

2017 ◽  
Vol 42 (10) ◽  
pp. 1044-1053
Author(s):  
Andrew W. Leslie ◽  
Joel L. Lanovaz ◽  
Justin W. Andrushko ◽  
Jonathan P. Farthing
Keyword(s):  
Eccentric Exercise ◽  
Training Group ◽  
Strength Loss ◽  
Repeated Bout Effect ◽  
Eccentric Training ◽  
Priming Phase ◽  
Single Bout ◽  
Flexibility Training ◽  
Repeated Bout ◽  
Knee Flexors

Both the repeated-bout effect and increased flexibility have been linked to reduced muscle damage, fatigue, and strength loss after intense eccentric exercise. Our purpose was to compare the eccentric-training (ECC) response after first priming the muscles with either static flexibility training or a single intense bout of eccentric exercise. Twenty-five participants were randomly assigned to flexibility training (n = 8; 3×/week; 30 min/day), a single bout of intense eccentric exercise (n = 9), or no intervention (control; n = 8) during a 4-week priming phase, prior to completing a subsequent 4-week period of eccentric training of the knee flexors. Testing was completed prior to the priming phase, before ECC, during acute ECC (0 h, 24 h, and 48 h after bouts 1 and 4), and after ECC. Measures included muscle thickness (MT; via ultrasound); isometric, concentric, and eccentric strength; muscle power (dynamometer); electromyography; range of motion; optimal angle of peak torque; and soreness (visual analog scale). Flexibility training and single-bout groups had 47% less soreness at 48 h after the first bout of ECC compared with control (p < 0.05). The flexibility training group had 10% less soreness at 48 h after the fourth ECC bout compared with both the single-bout and control groups (p < 0.05). Isometric strength loss was attenuated for the flexibility training group (−9%) after the fourth ECC bout compared with control (−19%; p < 0.05). All groups had similar increases in strength, MT, and power after ECC (p < 0.05). Prior flexibility training may be more effective than a single session of eccentric exercise in reducing adverse symptoms during the acute stages of eccentric training; however, these benefits did not translate into greater performance after training.

scholarly journals Influence of Maturation Status on Eccentric Exercise-Induced Muscle Damage and the Repeated Bout Effect in Females

2018 ◽  
Vol 8 ◽  
Author(s):  
Ming-Ju Lin ◽  
Kazunori Nosaka ◽  
Chih-Chiao Ho ◽  
Hsin-Lian Chen ◽  
Kuo-Wei Tseng ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Repeated Bout Effect ◽  
Exercise Induced ◽  
Repeated Bout
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