Current Model

1957 ◽  
Vol 2 (6) ◽  
pp. 153-155
Author(s):  
W. K. ESTES
Keyword(s):  
Author(s):  
M. Shlepr ◽  
R. L. Turner

Calcification in the echinoderms occurs within a limited-volume cavity enclosed by cytoplasmic extensions of the mineral depositing cells, the sclerocytes. The current model of this process maintains that the sheath formed from these cytoplasmic extensions is syncytial. Prior studies indicate that syncytium formation might be dependent on sclerocyte density and not required for calcification. This model further envisions that ossicles formed de novo nucleate and grow intracellularly until the ossicle effectively outgrows the vacuole. Continued ossicle growth occurs within the sheath but external to the cell membrane. The initial intracellular location has been confirmed only for elements of the echinoid tooth.The regenerating aboral disc integument of ophiophragmus filograneus was used to test the current echinoderm calcification model. This tissue is free of calcite fragments, thus avoiding questions of cellular engulfment, and ossicles are formed de novo. The tissue calcification pattern was followed by light microscopy in both living and fixed preparations.


1997 ◽  
Vol 92 (3) ◽  
pp. 609-617 ◽  
Author(s):  
RICCARDO ZANASI ◽  
PAOLO LAZZERETTI

2000 ◽  
Vol 12 (1) ◽  
pp. 65-86 ◽  
Author(s):  
R. La ◽  
B. Benoist ◽  
B. de Barmon ◽  
M. Talvard ◽  
R. Lengelle ◽  
...  

2013 ◽  
Vol 1 (3) ◽  
pp. 9
Author(s):  
Jennifer Lee Brady ◽  
Annie Hoang ◽  
Olivia Siswanto ◽  
Jordana Riesel ◽  
Jacqui Gingras

Obtaining dietetic licensure in Ontario requires completion of a Dietitians of Canada (DC) accredited four-year undergraduate degree in nutrition and an accredited post-graduate internship or combined Master’s degree program. Given the scarcity of internship positions in Ontario, each year approximately two-thirds of the eligible applicants who apply do not receive a position XX, XX, XX, XX, XX, XX, in press). Anecdotally, not securing an internship position is known to be a particularly disconcerting experience that has significant consequences for individuals’ personal, financial, and professional well-being. However, no known empirical research has yet explored students’ experiences of being unsuccessful in applying for internship positions. Fifteen individuals who applied between 2005 and 2009 to an Ontario-based dietetic internship program, but were unsuccessful at least once, participated in a one-on-one semi-structured interview. Findings reveal that participants’ experiences unfold successively in four phases that are characterized by increasingly heightened emotional peril: naïveté, competition, devastation, and frustration. The authors conclude that the current model of dietetic education and training in Ontario causes lasting distress to students and hinders the future growth and vitality of the dietetic profession. Further research is required to understand the impact of the current model on dietetic educators, internship coordinators, and preceptors as coincident participants in the internship application process.


2015 ◽  
Vol 135 (10) ◽  
pp. 632-637 ◽  
Author(s):  
Yoshitaka Tokunaga ◽  
Makoto Masutani
Keyword(s):  

2020 ◽  
Vol 26 (9) ◽  
pp. 1951-1969
Author(s):  
S.A. Chernikova

Subject. The article considers the need to study the financing of investment and innovation processes and creating an effective system of project financing. Objectives. The purpose is to search for new opportunities to enhance the competitive advantages of enterprises of the dairy subcomplex, to ensure their financial stability and steady position in specialized agricultural food-product markets. Methods. The study draws on the theoretical and methodological approach to the impact of project management of innovation and investment activities on improving the efficiency of the project financing system and financial stability of enterprises operating in the dairy subcomplex. Results. The findings show that four levels can be distinguished in the formation and improvement of the system of project financing and the management of innovation and investment activities, depending on the depth of transformation. The principle that provides the integration of the said system with the current model of management of the dairy subcomplex enterprise is defined as a driver. The paper offers a number of levels of the system transformation to gain competitive advantages. Conclusions. I present a mechanism for creating and improving the system of project financing and the management of innovation and investment activities, and a mechanism for interaction of the network of automated information systems, intended to make management decisions, with the automation of information support to innovative solutions.


2018 ◽  
Author(s):  
Carla Isobel Elliff

Coral reefs provide important ecosystem services to coastal communities. The Archipelago of Tinhar?e andBoipeba, Bahia, Brazil, are mostly surrounded by fringing reefs, which have undergone several chronichuman impacts. The objective of the present study was to apply an ecosystem-based approach byanalyzing the ecosystem services provided by the coral reefs of the Archipelago of Tinhar?e and Boipeba inorder to support management actions and serve as a tool for coastal management. Ecosystem serviceswere assessed through the observation of environmental indicators of their occurrence and by using asuite of models from the Integrated Valuation of Environmental Services and Tradeoffs (InVEST) softwarecombined with data from the Atlantic and Gulf Rapid Reef Assessment (AGRRA) protocol database. Theservices of greatest occurrence were food provision, habitat maintenance, shoreline protection andrecreation. While the main stressful factors were tourism activities, the absence of a sewage system andfisheries. The coral reefs presented potential for shoreline protection along 50.5% of the islands. Moreover,46.8% of the shoreline would present moderate to high vulnerability in case of coral reef disappearance.The coincidence of areas with high risk of loss in the capacity to provide services and highvulnerability in the scenario of absence of reefs is concerning. Thus, the current model for tourism usedin the area should be altered, as should new management strategies be implemented, which can bringbenefits and avoid reef decline.


Author(s):  
Jurica Novak ◽  
Maria A. Grishina ◽  
Vladimir A. Potemkin

: In this letter the newly introduced approach based on the radial distribution function (RDF) weighted by the number of va-lence shell electrons is applied for a series of HIV-1 protease enzyme and its complexes with inhibitors to evaluate the influ-ence of hydrogen atoms on the performance of the model. The multiple linear regression method was used for the selection of the relevant descriptors. Two groups of residues having dominant contribution to the RDF descriptor are identified as relevant for the inhibition. In the first group are residues like Arg8, Asp25, Thr26, Gly27 and Asp29, which establish direct interaction with the inhibitor, while the second group consists of the amino acids at the interface of the two homodimer sub-units or with the solvent. The crucial motif pointed out by our approach as the most important for inhibition of the enzyme’s activity and present in all inhibitors is hydroxyl group that establish hydrogen bond with Asp25 side chain. Additionally, the comparison to the model without hydrogen showed that both models are of similar quality, but the downside of the current model is the need for the determination of residues’ protonation states.


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