Early life adversity and increased delay discounting: Findings from the Family Health Patterns project.

STratifying Resilience and Depression Longitudinally (STRADL) is a population-based study built on the Generation Scotland: Scottish Family Health Study (GS:SFHS) resource. The aim of STRADL is to subtype major depressive disorder (MDD) on the basis of its aetiology, using detailed clinical, cognitive, and brain imaging assessments. The GS:SFHS provides an important opportunity to study complex gene-environment interactions, incorporating linkage to existing datasets and inclusion of early-life variables for two longitudinal birth cohorts. Specifically, data collection in STRADL included: socio-economic and lifestyle variables; physical measures; questionnaire data that assesses resilience, early-life adversity, personality, psychological health, and lifetime history of mood disorder; laboratory samples; cognitive tests; and brain magnetic resonance imaging. Some of the questionnaire and cognitive data were first assessed at the GS:SFHS baseline assessment between 2006-2011, thus providing longitudinal measures relevant to the study of depression, psychological resilience, and cognition. In addition, routinely collected historic NHS data and early-life variables are linked to STRADL data, further providing opportunities for longitudinal analysis. Recruitment has been completed and we consented and tested 1,188 participants.

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Defining the phenotype of young adults with family histories of alcohol and other substance use disorders: Studies from the family health patterns project

Addictive Behaviors ◽

10.1016/j.addbeh.2017.10.014 ◽

2018 ◽

Vol 77 ◽

pp. 247-254 ◽

Cited By ~ 8

Author(s):

Ashley Acheson ◽

Andrea S. Vincent ◽

Andrew J. Cohoon ◽

William R. Lovallo

Keyword(s):

Substance Use ◽

Young Adults ◽

Substance Use Disorders ◽

Family Health ◽

Family Histories ◽

Health Patterns ◽

The Family

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FERTILITY INTENTIONS AND EARLY LIFE HEALTH STRESS AMONG WOMEN IN EIGHT INDIAN CITIES: TESTING THE REPRODUCTIVE ACCELERATION HYPOTHESIS

Journal of Biosocial Science ◽

10.1017/s0021932014000261 ◽

2014 ◽

Vol 47 (5) ◽

pp. 632-649 ◽

Cited By ~ 1

Author(s):

SANGITA KULATHINAL ◽

MINNA SÄÄVÄLÄ

Keyword(s):

Early Life ◽

Life History Theory ◽

Adult Height ◽

Family Health ◽

Fertility Intentions ◽

Urban Environments ◽

Early Life Adversity ◽

Childhood Health ◽

Multinomial Logistic Model ◽

Indian Cities

SummaryIn life history theory, early life adversity is associated with an accelerated reproductive tempo. In harsh and unpredictable conditions in developing societies fertility is generally higher and the reproductive tempo faster than in more secure environments. This paper examines whether differences in female anthropometry, particularly adult height, are associated with fertility intentions of women in urban environments in India. The study population consists of women aged 15–29 (N=4485) in slums and non-slums of eight Indian cities in the National Family Health Survey (NFHS) of 2005–2006. Adult height is taken as a proxy for early childhood health and nutritional condition. Fertility intentions are examined by using two variables: the desire to have a child or another child, and to have it relatively soon, as indicative of accelerated reproductive scheduling. Evidence supporting the acceleration hypothesis is found in two urban frames out of 26 examined in a two-staged multinomial logistic model. In three cases, the relationship between fertility intentions and height is the opposite than expected by the acceleration hypothesis: taller women have a higher predictive probability of desiring a(nother) child and/or narrower birth spacing. Potential explanations for the partly contradictory relationship between the childhood health indicator and fertility intentions are discussed.

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Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments

Wellcome Open Research ◽

10.12688/wellcomeopenres.15538.1 ◽

2019 ◽

Vol 4 ◽

pp. 185 ◽

Cited By ~ 5

Author(s):

Tina Habota ◽

Anca-Larisa Sandu ◽

Gordon D. Waiter ◽

Christopher J. McNeil ◽

J. Douglas Steele ◽

...

Keyword(s):

Psychological Health ◽

Early Life ◽

Brain Magnetic Resonance Imaging ◽

Family Health ◽

Population Based ◽

Health Study ◽

Birth Cohorts ◽

Early Life Adversity ◽

Generation Scotland ◽

History Of

STratifying Resilience and Depression Longitudinally (STRADL) is a population-based study built on the Generation Scotland: Scottish Family Health Study (GS:SFHS) resource. The aim of STRADL is to subtype major depressive disorder (MDD) on the basis of its aetiology, using detailed clinical, cognitive, and brain imaging assessments. The GS:SFHS provides an important opportunity to study complex gene-environment interactions, incorporating linkage to existing datasets and inclusion of early-life variables for two longitudinal birth cohorts. Specifically, data collection in STRADL included: socio-economic and lifestyle variables; physical measures; questionnaire data that assesses resilience, early-life adversity, personality, psychological health, and lifetime history of mood disorder; laboratory samples; cognitive tests; and brain magnetic resonance imaging. Some of the questionnaire and cognitive data were first assessed at the GS:SFHS baseline assessment between 2006-2011, thus providing longitudinal measures of depression and resilience. Similarly, routine NHS data and early-life variables are linked to STRADL data, further providing opportunities for longitudinal analysis. Recruitment has been completed and we consented and tested 1,188 participants.

Download Full-text