Cirrhosis and liver tumours in a closed colony of golden hamsters

Munkahelyünkön 2004–2014 között 273 elektív műtét történt benignus májelváltozás miatt. 83 esetben laparoszkópos (LAP) beavatkozásra került sor: cystafenestratio 52, májresectio 31 esetben történt. A LAP resectiókat hasonló demográfiai és klinikai jellemzőkkel bíró betegek nyitott műtéteivel összehasonlítva megállapítható, hogy a műtéti idő a LAP csoportban (113,7 perc) szignifikánsan hosszabb volt, mint a nyitott műtéteknél (89,5 perc), a kórházi ápolási idő viszont rövidebb (5,8 vs 9,1 nap). Posztoperatív szövődmény a LAP csoportban nem volt, nyitott műtétek után két sebgennyedés, egy UH-vezérelt drainezést igénylő epegyülem fordult elő. A nyitott csoportban 4, a LAP csoportban 3 beteg igényelt transzfúziót. Műtéti halálozás nem volt, reoperációra nem került sor. A közleményben részletezett műtéti technika biztonságos resectiót tesz lehetővé a máj nehezen hozzáférhető, 7–8. szegmentuma területén is. Az eredmények alapján a LAP májresectio megfelelő preoperatív vizsgálatok birtokában választható módszer májdaganatok sebészi kezelésére.

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Magnetic Resonance Imaging of Uncommon Hepatic Mesenchymal Tumours: Haemangioendothelioma and Angiosarcoma

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405614666180628160809 ◽

2019 ◽

Vol 15 (4) ◽

pp. 362-368

Author(s):

Andrzej Cieszanowski ◽

Agnieszka Anysz-Grodzicka ◽

Joanna Podgorska ◽

Beata Jagielska ◽

Jakub Pałucki

Keyword(s):

Contrast Enhancement ◽

Correct Diagnosis ◽

Malignant Potential ◽

Hepatobiliary Phase ◽

Imaging Features ◽

Liver Tumours ◽

Aged Woman ◽

High Apparent Diffusion Coefficient ◽

Adc Values ◽

Mesenchymal Tumours

<P>Background: Primary Hepatic Epithelioid Haemangioendothelioma (HEHE) and Primary Hepatic Angiosarcoma (PHA) are rare mesenchymal tumours with different malignant potential. Whereas HEHE demonstrates low to intermediate malignant potential, PHA is an aggressive malignancy with poor prognosis. The knowledge of typical imaging features of these lesions may facilitate correct diagnosis; however, the ultimate diagnosis of HEHE and PHA is based on histopathologic examination. </P><P> Discussion: The most typical findings helpful in diagnosing HEHE are: Presence of multiple, confluent nodules located at the liver periphery (in young to middle-aged woman), retraction of the liver capsule, marked hyperintensity on T2-weighted images, “target-sign” appearance, progressive centripetal contrast enhancement, and relatively high Apparent Diffusion Coefficient (ADC) values. More than ≥50% of nodules are hyper- or isointense on Hepatobiliary Phase (HBP) images. Conclusion: The imaging features suggestive of PHA are: Occurrence of metastases (lungs, spleen) at the time of diagnosis, presence of a large dominant mass with smaller satellites, heterogeneity and areas of haemorrhage in a dominant mass, progressive contrast enhancement, slightly elevated ADC values as compared to other malignant liver tumours.</P>

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Characterization of Serum Dehydroepiandrosterone Secretion in Golden Hamsters

Proceedings of The Society for Experimental Biology and Medicine ◽

10.1046/j.1525-1373.2000.22432.x ◽

2000 ◽

Vol 224 (4) ◽

pp. 278-284 ◽

Cited By ~ 30

Author(s):

David R. Pieper ◽

Catherine A. Lobocki

Keyword(s):

Golden Hamsters

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466 Resection or Enucleation for Extremely Giant Hepatic Haemangiomata? A Case Report and Review of The Literature

British Journal of Surgery ◽

10.1093/bjs/znab134.284 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

R E Fraser ◽

G R Layton ◽

L L Kuan ◽

A R Dennison

Keyword(s):

Expectant Management ◽

Evidence Base ◽

Primary Treatment ◽

Cavernous Haemangioma ◽

Liver Tumours ◽

Case Presentation ◽

Best Management ◽

Anatomical Liver Resection ◽

Benign Liver

Abstract Background Cavernous hepatic haemangiomas are benign liver tumours and although common when small, giant haemangiomas (usually accepted as being greater than 10cm) are infrequent. Treatment is indicated in patients who are symptomatic or if diagnosis is unclear, although with giant haemangiomas, many support expectant management of asymptomatic lesions due to the risk of major complications. Traditionally hepatic resection has been the primary treatment option for these lesions, but a variety of other techniques, including enucleation, have been described as safe and effective alternatives. There remains equipoise in respect of the best management of giant haemangiomas above 10cm. Cases of such size are rare and so there is a paucity of data available. Case presentation We present a case of a 65-year-old male who underwent successful anatomical liver resection for a 5kg giant cavernous haemangioma of 26cm diameter following its incidental identification during an ultrasound scan. We also discuss and compare the role of resection and enucleation for the treatment of haemangiomata greater than 20cm in diameter. Conclusions This case demonstrates successful resection of an unusually giant haemangioma which, in contrast to the majority of literature, provides a valuable addition to the limited evidence base for management of this condition by anatomical resection.

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