scholarly journals Hydroxypropyl methylcellulose in extracapsular cataract surgery with intraocular lens implantation: Intraocular pressure and inflammatory response

Eye ◽  
1990 ◽  
Vol 4 (1) ◽  
pp. 121-126 ◽  
Author(s):  
L C Chumbley ◽  
A M Morgan ◽  
I Musallam
2021 ◽  
Vol 2 (3) ◽  
pp. 142-147
Author(s):  
Lei Fang ◽  
◽  
Jian-Cen Tang ◽  
Hao Chu ◽  
Ji Xu ◽  
...  

AIM: To explore whether there is an inflammatory response in the contralateral eye after cataract surgery in the first eye, and try to explore the development of the inflammatory response. METHODS: In this paired-sample study, aqueous humor samples from 37 bilateral age-related cataract patients were collected just before each cataract surgery. Samples collected during the first-eye cataract surgery were marked as Group A, samples collected during the second-eye cataract surgery were marked as Group B. In addition, the samples were classified into five groups according to different operation intervals between the first and the second cataract surgery. Finally, the concentration of 13 selected cytokines (including TNF-α, IL-6, IL-8, CCL2/MCP-1, IL-6 Rα, IL-1 ra, MIP-1α, MIP-1d, CCL4, IL-2, CXCL9, TIMP-1, CCL11) in aqueous humor samples was detected by Luminex-200 (RnD) simultaneously in accordance with the manufacturer’s instructions. RESULTS: Among the 13 selected cytokines, there was statistically difference between the first and the second eyes in concentration of IL-6, MIP-1α, CCL2/MCP-1, TNF-α, MIP-1d, IL-2 and TIMP-1 (P<0.05), and the expression levels of all these seven cytokines in the second eyes were higher than those in the first eyes, and the concentration of IL-6 and MIP-1a in the second eyes was significantly higher than that in the first eyes (P<0.001). Compared with the first eyes, the concentration of CCL4, CCL11, IL-6Rα, CXCL9, and IL-1ra in the second eyes only showed slightly increase, while IL-8 showed a slight decrease, all with no statistically difference (all P>0.05). The concentration differences of IL-6, MCP-1/CCL2, IL-2, MIP-1d between the first eyes and the second eyes were most obvious at the third week after phacoemulsification combined with intraocular lens implantation (PHACO+IOL) in the first eye. CONCLUSION: This study revealed that there may be an inflammatory response in the contralateral eye after cataract surgery in the first eye, and the inflammatory response in the second eye appears to be most significant at the third week after phacoemulsification combined with intraocular lens implantation (PHACO+IOL) in the first eye.


2006 ◽  
Vol 13 (02) ◽  
pp. 225-230
Author(s):  
NAEEM RUSTAM ◽  
IRSHAD HUSSAIN ◽  
MUHAMMAD WASEEM

Objective: To investigate the course of intraocular pressure after cataract surgery in patients havingpseudo exfoliation syndrome but without any evidence of glaucoma. Design: Prospective age-matched comparativetype. Place and Duration of Study: Department of Ophthalmology, Combined Military Hospital, Peshawar and MilitaryHospital, Rawalpindi. From 1 November 2003 to 30 April st th 2004. Patients and Methods: Ninety five patients havingcataract, were divided into two groups. Group I consisted of forty five patients with pseudo exfoliation syndrome andGroup II comprised control group of fifty patients not having pseudo exfoliation. All the patients underwent extracapsularcataract extraction with posterior chamber intraocular lens implantation. The intra- ocular pressure wasmeasured pre-operatively as well as on 7th post-operative day, 1st and 3rd post-operative months, in addition to otherpre- and post-operative evaluation. Results: Statistically, there was no significant difference in the pre-operativeintraocular pressure between the two study groups. At 7th post-operative day, the intraocular pressure was below 18mm of Hg in all the patients. First and 3rd month after the surgery, a decrease in intraocular pressure was observed.The inter-group differences in intraocular pressures at 1st and 3rd post-operative months were statistically not significant.Conclusion: Seven days after extra-capsular cataract extraction with posterior chamber intraocular lens implantation,no increase in intraocular pressure was observed in the eyes with pseudo exfoliation syndrome. Three months aftercataract surgery, intraocular pressure levels decreased in eyes with pseudo exfoliation syndrome similarly as in controlgroup.


2021 ◽  
pp. 659-663
Author(s):  
Shimon Kurtz ◽  
Maayan Fradkin

We describe a case of Urrets-Zavalia syndrome (UZS) in a healthy 56-year-old woman who underwent femtosecond-assisted phacoemulsification with intraocular lens implantation in both eyes. One month after an uneventful postoperative course in the left eye, the right eye was operated. Dilated pupil which was nonreactive to light appeared on day 21 postoperatively. This was discovered upon examination following anterior chamber inflammatory reaction which occurred 2 weeks following her surgery. Our case report emphasizes the importance and danger in developing UZS even if the reaction in the anterior chamber does not occur immediately after surgery. In addition, the importance of intraocular pressure follow-up in the period after UZS is acknowledged.


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