A comparative study of computerised visual field testing and optic disc morphometric parameters in the follow-up of primary open angle glaucoma

Introduction. Morning glory syndrome (MGS) is a rare congenital optic disc anomaly, first reported in 1970. MGS is a nonprogressive and untreatable condition, which usually occurs as an isolated ocular anomaly, and can be associated with the increased incidence of nonrhegmatogenous retinal detachment, and also with strabismus, afferent pupillary defect, visual field defects, presence of hyaloids artery remnants, ciliary body cyst, congenital cataract, lid hemangioma and preretinal gliosis. Case Outline. We report a clinical case of MGS associated with primary open angle glaucoma. The use of sophisticated diagnostic tools, such as retinal tomography and visual field testing is limited if multiple eye conditions are present, since optic disc does not have ?usual? appearance that can be analyzed according to standard statistical databases. Conclusion. In treating and follow up of glaucoma cases associated with other diseases and conditions that affect the appearance and function of the optic nerve head, sometimes the use of modern technological methods is limited due to difficult interpretation of the obtained results.

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Development of a new strategy of visual field testing for macular dysfunction in patients with open angle glaucoma

Japanese Journal of Ophthalmology ◽

10.1007/s10384-013-0258-4 ◽

2013 ◽

Vol 57 (5) ◽

pp. 457-462 ◽

Cited By ~ 7

Author(s):

Kazuko Omodaka ◽

Shiho Kunimatsu-Sanuki ◽

Ryu Morin ◽

Satoru Tsuda ◽

Yu Yokoyama ◽

...

Keyword(s):

Visual Field ◽

Open Angle Glaucoma ◽

Field Testing ◽

Open Angle ◽

Visual Field Testing ◽

New Strategy

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Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden.

10.21203/rs.3.rs-34864/v2 ◽

2020 ◽

Author(s):

Marcelo Ayala

Keyword(s):

Visual Field ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

T Test ◽

Open Angle ◽

Visual Field Progression ◽

Exfoliation Glaucoma ◽

The Difference ◽

Glaucoma Group

Abstract Background: The present study aimed to compare visual field progression in new-diagnosed exfoliation versus open-angle glaucoma patients. Methods: Retrospective study. The study included patients with new-diagnosed primary open-angle and exfoliation glaucoma. All patients were followed for three years with reliable visual fields. At least five reliable fields were needed for inclusion. Exfoliation and open-angle glaucoma were defined based on the European Glaucoma Society guidelines. Visual field evaluation was performed using the software threshold 24-2 of the Humphrey Field Analysis. Outcomes: Visual field progression. For visual field progression, three different strategies were used: mean deviation (MD), visual field index (VFI), and the guided progression analysis (GPA). Results: The study included 128 subjects, of the 54 in the open-angle and 74 in the exfoliation glaucoma group. The MD difference values were higher in the exfoliation (-3.17 dB) than in the primary open-angle (-1.25 dB) glaucoma group in the three-year follow-up period. The difference between groups was significant (t-test, p=<0.001). The difference in VFI was calculated for the three years follow-up period. The difference was higher in the exfoliation (-7.65%) than in the primary open (-1.90%) glaucoma group (t-test, p=<0.001). The GPA showed progression in 58% of cases in exfoliation, and 13% in primary open glaucoma group (Chi-square, p=<0.001). Conclusion: The present study found a more frequent and faster visual field progression in exfoliation than in primary open-angle glaucoma patients. New-diagnosed exfoliation glaucoma patients must be controlled and treated more strictly than primary open-angle glaucoma patients to avoid visual field deterioration.

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Study of correlation of retinal nerve fiber layer thickness and optic disc parameters with visual field changes in glaucoma suspects and diagnosed cases of primary open angle glaucoma

MedPulse International Journal of Ophthalmology ◽

10.26611/1009913 ◽

2019 ◽

Vol 9 (1) ◽

pp. 10-13

Author(s):

Latha C ◽

◽

Praveen Kumar G S ◽

Keyword(s):

Visual Field ◽

Nerve Fiber ◽

Layer Thickness ◽

Optic Disc ◽

Retinal Nerve Fiber Layer ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Open Angle ◽

Fiber Layer ◽

Nerve Fiber Layer Thickness

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Morphological characteristics of parapapillary atrophy and subsequent visual field progression in primary open-angle glaucoma

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2019-315477 ◽

2020 ◽

pp. bjophthalmol-2019-315477 ◽

Cited By ~ 1

Author(s):

Ahnul Ha ◽

Yong Woo Kim ◽

Jinho Lee ◽

Eunoo Bak ◽

Young Soo Han ◽

...

Keyword(s):

Visual Field ◽

Optic Disc ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Morphological Characteristics ◽

Rank Test ◽

Cumulative Probability ◽

Open Angle ◽

Irregularity Index ◽

Parapapillary Atrophy

Background/AimsTo investigate the associations between the morphological characteristics of beta-zone parapapillary atrophy (β-zone PPA) and subsequent visual field (VF) progression in eyes with primary open-angle glaucoma (POAG).MethodsOne hundred and twenty-one POAG eyes with β-zone PPA along with 48 normal eyes with β-zone PPA were included. β-zone PPA area was calculated based on the PPA pixel area/optic-disc pixel area ratio and the optical coherence tomography (OCT)-measured disc area. β-zone PPA margin irregularity was quantified as a function of both area (A) and perimeter (P, calculated as 1/(4πA/P²)). VF progression was defined using standard automated perimetry’s guided progression analysis software.ResultsOf the 121 POAG eyes, 49 (40.5%) showed VF progression during the 10.1±1.9 years of follow-up. The baseline β-zone PPA area was similar among the three groups (Progressors, Non-progressors and Controls, p=0.995). However, the β-zone PPA irregularity index was significantly higher in the Progressors (p<0.001). The cumulative probability of VF progression was greater in the higher PPA irregularity index group (p<0.001, log-rank test). A Cox proportional hazards model showed the significant influences of optic disc haemorrhage (HR: 2.661, p=0.034) and higher baseline PPA irregularity index (HR: 1.455, p=0.007) on subsequent progression.ConclusionsIn POAG eyes, baseline β-zone PPA margin regularity was significantly associated with subsequent VF progression. Irregular margin of β-zone PPA might be the mark of vulnerability in the parapapillary area to further glaucomatous damage.

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Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden

BMC Ophthalmology ◽

10.1186/s12886-020-01592-w ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Marcelo Ayala

Keyword(s):

Visual Field ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

T Test ◽

Open Angle ◽

Visual Field Progression ◽

Exfoliation Glaucoma ◽

The Difference ◽

Glaucoma Group

Abstract Background The present study aimed to compare visual field progression in new-diagnosed exfoliation versus open-angle glaucoma patients. Methods Retrospective study. The study included patients with new-diagnosed primary open-angle and exfoliation glaucoma. All patients were followed for 3 years with reliable visual fields. At least five reliable fields were needed for inclusion. Exfoliation and open-angle glaucoma were defined based on the European Glaucoma Society guidelines. Visual field evaluation was performed using the software threshold 24–2 of the Humphrey Field Analysis. Outcomes: Visual field progression. For visual field progression, three different strategies were used: mean deviation (MD), visual field index (VFI), and the guided progression analysis (GPA). Results The study included 128 subjects, of the 54 in the open-angle and 74 in the exfoliation glaucoma group. The MD difference values were higher in the exfoliation (− 3.17 dB) than in the primary open-angle (− 1.25 dB) glaucoma group in the three-year follow-up period. The difference between groups was significant (t-test, p = < 0.001). The difference in VFI was calculated for the 3 years follow-up period. The difference was higher in the exfoliation (− 7.65%) than in the primary open (− 1.90%) glaucoma group (t-test, p = < 0.001). The GPA showed progression in 58% of cases in exfoliation, and 13% in primary open glaucoma group (Chi-square, p = < 0.001). Conclusion The present study found a more frequent and faster visual field progression in exfoliation than in primary open-angle glaucoma patients. New-diagnosed exfoliation glaucoma patients must be controlled and treated more strictly than primary open-angle glaucoma patients to avoid visual field deterioration.

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