scholarly journals Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering

2014 ◽  
Vol 6 (7) ◽  
pp. 614-622 ◽  
Author(s):  
Dan Fu ◽  
Jing Zhou ◽  
Wenjing Suzanne Zhu ◽  
Paul W. Manley ◽  
Y. Karen Wang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Stimulated Raman Scattering ◽  
Living Cells ◽  
Intracellular Distribution ◽  
Stimulated Raman

scholarly journals Utilizing Stimulated Raman Scattering Microscopy To Study Intracellular Distribution of Label-Free Ponatinib in Live Cells

2019 ◽  
Vol 63 (5) ◽  
pp. 2028-2034 ◽  
Author(s):  
Kristel Sepp ◽  
Martin Lee ◽  
Marie T. J. Bluntzer ◽  
G. Vignir Helgason ◽  
Alison N. Hulme ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Stimulated Raman Scattering ◽  
Intracellular Distribution ◽  
Live Cells ◽  
Label Free ◽  
Stimulated Raman

scholarly journals Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering

2018 ◽  
Vol 54 (2) ◽  
pp. 152-155 ◽  
Author(s):  
Rong Long ◽  
Luyuan Zhang ◽  
Lingyan Shi ◽  
Yihui Shen ◽  
Fanghao Hu ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Raman Scattering ◽  
Glucose Uptake ◽  
Imaging Technique ◽  
Stimulated Raman Scattering ◽  
Living Cells ◽  
Stimulated Raman

A two-color vibrational imaging technique for simultaneously mapping glucose uptake and incorporation activity inside living cells is reported.

scholarly journals A ratiometric Raman probe for live-cell imaging of hydrogen sulfide in mitochondria by stimulated Raman scattering

The Analyst ◽  
2018 ◽  
Vol 143 (20) ◽  
pp. 4844-4848 ◽  
Author(s):  
Chen Zeng ◽  
Fanghao Hu ◽  
Rong Long ◽  
Wei Min
Keyword(s):  
Hydrogen Sulfide ◽  
Raman Scattering ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Stimulated Raman Scattering ◽  
Living Cells ◽  
Live Cell ◽  
Raman Probe ◽  
Stimulated Raman

We develop a ratiometric Raman probe for visualizing hydrogen sulfide in living cells as the first alkyne-based sensor for SRS microscopy.

scholarly journals Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy

2017 ◽  
Vol 8 (8) ◽  
pp. 5606-5615 ◽  
Author(s):  
William J. Tipping ◽  
Martin Lee ◽  
Alan Serrels ◽  
Valerie G. Brunton ◽  
Alison N. Hulme
Keyword(s):  
Raman Scattering ◽  
Therapeutic Response ◽  
Stimulated Raman Scattering ◽  
Living Cells ◽  
Drug Uptake ◽  
Drug Concentrations ◽  
Stimulated Raman

Stimulated Raman scattering (SRS) microscopy in tandem with bioorthogonal Raman labelling enables intracellular drug concentrations, distribution and therapeutic response to be measured in living cells.

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