scholarly journals Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

Oncogene ◽  
2009 ◽  
Vol 28 (34) ◽  
pp. 3009-3021 ◽  
Author(s):  
A Gualberto ◽  
M Pollak
Keyword(s):  
Clinical Trial ◽  
Growth Factor ◽  
Growth Factor Receptor ◽  
Insulin Like Growth Factor ◽  
Future Directions ◽  
Early Clinical Trial ◽  
Clinical Trial Results

scholarly journals Role of Insulin-Like Growth Factor Receptor 2 across Muscle Homeostasis: Implications for Treating Muscular Dystrophy

Cells ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 441 ◽  
Author(s):  
Yvan Torrente ◽  
Pamela Bella ◽  
Luana Tripodi ◽  
Chiara Villa ◽  
Andrea Farini
Keyword(s):  
Growth Factor ◽  
Growth Factor Receptor ◽  
Muscle Disease ◽  
Insulin Like Growth Factor ◽  
Related Disease ◽  
Research Findings ◽  
Novel Approaches ◽  
And Migration ◽  
Muscle Homeostasis

The insulin-like growth factor 2 receptor (IGF2R) plays a major role in binding and regulating the circulating and tissue levels of the mitogenic peptide insulin-like growth factor 2 (IGF2). IGF2/IGF2R interaction influences cell growth, survival, and migration in normal tissue development, and the deregulation of IGF2R expression has been associated with growth-related disease and cancer. IGF2R overexpression has been implicated in heart and muscle disease progression. Recent research findings suggest novel approaches to target IGF2R action. This review highlights recent advances in the understanding of the IGF2R structure and pathways related to muscle homeostasis.

Prognostic role of insulin-like growth factor receptor-1 expression in small cell lung cancer

Apmis ◽  
2009 ◽  
Vol 117 (12) ◽  
pp. 861-869 ◽  
Author(s):  
MYUNG HEE CHANG ◽  
JEEYUN LEE ◽  
JOUNGHO HAN ◽  
YEON HEE PARK ◽  
JIN SEOK AHN ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Growth Factor ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Growth Factor Receptor ◽  
Small Cell ◽  
Insulin Like Growth Factor ◽  
Small Cell Lung ◽  
Prognostic Role

The role of the type 1 insulin-like growth factor receptor in bladder cancer

2003 ◽  
Vol 2 (6) ◽  
pp. 52
Author(s):  
M.A Rochester ◽  
N.S Patel ◽  
G.O Hellawell ◽  
S.F Brewster ◽  
V.M Macaulay
Keyword(s):  
Bladder Cancer ◽  
Growth Factor ◽  
Growth Factor Receptor ◽  
Insulin Like Growth Factor

Growth hormone (GH) and insulin-like growth factor-1 (ICF-1) in the elderly: clinical trial results

2002 ◽  
Vol 35 ◽  
pp. 81-92 ◽  
Author(s):  
G.P. Ceda ◽  
E. Dall’aglio ◽  
I. Salimbeni ◽  
A. Rocci ◽  
F. Corradi ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Growth Hormone ◽  
Growth Factor ◽  
The Elderly ◽  
Insulin Like Growth Factor ◽  
Clinical Trial Results

The potential role of insulin-like growth factor receptor inhibitors in the treatment of advanced non-small cell lung cancer

2010 ◽  
Vol 19 (5) ◽  
pp. 631-639 ◽  
Author(s):  
Cesare Gridelli ◽  
Antonio Rossi ◽  
Maria Anna Bareschino ◽  
Clorinda Schettino ◽  
Paola Claudia Sacco ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Growth Factor ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Potential Role ◽  
Growth Factor Receptor ◽  
Small Cell ◽  
Insulin Like Growth Factor ◽  
Small Cell Lung
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