Zinc levels in neonatal life influence long-term neurodevelopment

Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse eventsin uteroare a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases are being elucidated, little is known about how we can intervene early in life to diminish the incidence and severity of these long-term diseases. This paper highlights the latest clinical and pharmaceutical studies addressing how dietary intervention in fetal and neonatal life may be able to prevent aspects of the metabolic syndrome associated with IUGR pregnancies.

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59 Short term elevation of cholesterol level in neonatal life and long term changes in aortic stiffness: insights from use of intravenous lipids

Heart ◽

10.1136/heartjnl-2011-300198.59 ◽

2011 ◽

Vol 97 (Suppl 1) ◽

pp. A37-A38

Author(s):

A. J. Lewandowski ◽

M. Lazdam ◽

E. Davis ◽

R. Poole ◽

J. Diesch ◽

...

Keyword(s):

Cholesterol Level ◽

Aortic Stiffness ◽

Short Term ◽

Neonatal Life ◽

Long Term Changes ◽

Intravenous Lipids

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Immunodeficiency and plasma zinc levels in children with Down's syndrome: A long-term follow-up of oral zinc supplementation

Clinical Immunology and Immunopathology ◽

10.1016/0090-1229(91)90137-y ◽

1991 ◽

Vol 58 (2) ◽

pp. 207-216 ◽

Cited By ~ 13

Author(s):

A. Stabile ◽

M.A. Pesaresi ◽

A.M. Stabile ◽

M. Pastore ◽

S.Miceli Sopo ◽

...

Keyword(s):

Zinc Supplementation ◽

Down's Syndrome ◽

Down’S Syndrome ◽

Plasma Zinc ◽

Long Term Follow Up ◽

Zinc Levels

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Oyster arsenic, cadmium, copper, mercury, lead and zinc levels in the northern South China Sea: long-term spatiotemporal distributions, combined effects, and risk assessment to human health

Environmental Science and Pollution Research ◽

10.1007/s11356-021-18150-6 ◽

2022 ◽

Author(s):

Lifei Wang ◽

Xuefeng Wang ◽

Haigang Chen ◽

Zenghuan Wang ◽

Xiaoping Jia

Keyword(s):

Risk Assessment ◽

South China Sea ◽

Human Health ◽

South China ◽

Northern South China Sea ◽

Combined Effects ◽

China Sea ◽

Lead And Zinc ◽

Zinc Levels

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Reduced hippocampal in vitro CA1 long-term potentiation in rat offsprings with increased circulating corticosterone during neonatal life

Neuroscience Letters ◽

10.1016/0304-3940(96)13126-8 ◽

1996 ◽

Vol 218 (1) ◽

pp. 72-74 ◽

Cited By ~ 9

Author(s):

M.R. Domenici ◽

P. Casolini ◽

A. Catalani ◽

V. Ruggieri ◽

L. Angelucci ◽

...

Keyword(s):

Long Term Potentiation ◽

Neonatal Life ◽

Term Potentiation

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Zinc Poisoning - Symptoms, Causes, Treatments

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557520666200414161944 ◽

2020 ◽

Vol 20 (15) ◽

pp. 1489-1498

Author(s):

Mehrdad Rafati Rahimzadeh ◽

Mehravar Rafati Rahimzadeh ◽

Sohrab Kazemi ◽

Ali Akbar Moghadamnia

Keyword(s):

Chelating Agents ◽

Lung Ventilation ◽

Zinc Toxicity ◽

Zinc Compounds ◽

The World ◽

Contaminated Food ◽

Zinc Levels ◽

Different Sources ◽

Protective Lung Ventilation

Zinc poisoning has been reported from many parts of the world. It is one of the global health problems that affect many organs, if exposed by inhalation of zinc vapors or by consumption of contaminated food and water. Long term exposure to zinc compounds from different sources such as air, water, soil, and food, lead to toxic effects on body systems, especially digestive, respiratory, and nerve systems, and also causes cancer. Zinc levels can be determined in blood, urine, hair, and nails. Patients with zinc toxicity need chelating agents, other pharmacological treatment, protective lung ventilation, extracorporeal membrane oxygenation (ECMO), and supportive care.

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