Understanding the relative contributions of prematurity and congenital anomalies to neonatal mortality

2022 ◽  
Author(s):  
Ciaran S. Phibbs ◽  
Molly Passarella ◽  
Susan K. Schmitt ◽  
Jeannette A. Rogowski ◽  
Scott A. Lorch
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies

Contribution of Congenital Anomalies to Neonatal Mortality Rates in Malta

2015 ◽  
Vol 29 (5) ◽  
pp. 401-406 ◽  
Author(s):  
Miriam Gatt ◽  
Kathleen England ◽  
Victor Grech ◽  
Neville Calleja
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies ◽  
Mortality Rates

scholarly journals Stillbirth and neonatal mortality in pregnancies complicated by major congenital anomalies: Findings from a large European cohort

2017 ◽  
Vol 37 (11) ◽  
pp. 1100-1111 ◽  
Author(s):  
Henk Groen ◽  
Katelijne Bouman ◽  
Anna Pierini ◽  
Judith Rankin ◽  
Anke Rissmann ◽  
...  
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies

scholarly journals Stillbirth and Neonatal Mortality in Pregnancies Complicated by Major Congenital Anomalies

2018 ◽  
Vol 73 (3) ◽  
pp. 131-132
Author(s):  
Henk Groen ◽  
Katelijne Bouman ◽  
Anna Pierini ◽  
Judith Rankin ◽  
Anke Rissmann ◽  
...  
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies

Changes in Infant Morbidity Associated with Decreases in Neonatal Mortality

PEDIATRICS ◽  
1983 ◽  
Vol 72 (3) ◽  
pp. 408-415
Author(s):  
Sam Shapiro ◽  
Marie C. McCormick ◽  
Barbara H. Starfield ◽  
Barbara Crawley
Keyword(s):  
Birth Weight ◽  
Developmental Delay ◽  
Neonatal Mortality ◽  
High Mortality ◽  
Congenital Anomalies ◽  
Mortality And Morbidity ◽  
Random Samples ◽  
Infant Morbidity

Neonatal mortality and morbidity among infants surviving to 1 year of age in eight geographic areas have been compared to determine whether recent decreases in mortality have affected the risk of infants having congenital anomalies or developmental delay. Mortality was obtained from birth and death records in 1976 and either 1978 or 1979; morbidity through home interviews with mothers of random samples of infants and developmental observations on the children. It is concluded that the decrease in mortality was not offset by increases in children with defects. Neonatal mortality decreased by 18% in this 2- to 3-year period; risk of congenital anomalies or developmental delay (all types combined) declined by 16% among the surviving infants. The reduction in risk was concentrated in the minor congenital anomalies or developmental delay category; the proportion of children with severe or moderate congenital anomalies or developmental delay did not change. Decreases occurred at every birth weight including the very low birth weights of 1,500 g or less, a subgroup with especially high mortality and morbidity resulting from perinatal events.

FACTORS PERTAINING TO PROLONGED PREGNANCY AND ITS OUTCOME

PEDIATRICS ◽  
1967 ◽  
Vol 40 (2) ◽  
pp. 202-212
Author(s):  
Michael A. Zwerdling
Keyword(s):  
New York ◽  
New York City ◽  
Child Health ◽  
Neonatal Mortality ◽  
York City ◽  
Congenital Anomalies ◽  
Development Studies ◽  
Term Infants ◽  
Health And Development ◽  
Prolonged Pregnancy

Pregnancies extending more than 3 weeks beyond the expected date of confinement were studied among 9,719 single, white births from the Child Health and Development Studies in Oakland, California, and 358,702 births representing all white, singleton pregnancies in New York City terminating from 1957 through 1959. The incidence of prolonged pregnancy was 7.3% in the Child Health and Development Studies and 5.4% in New York City. Younger women, primigravidas, and women of high parity showed an increased incidence. Fetal and neonatal mortality rates were approximately doubled in prolonged pregnancy in both Oakland and New York City. This relationship held for both primiparas and multiparas, for antepartum and intrapartum fetal deaths, and for all major causes of fetal and neonatal mortality. Post-term infants weighing less than 2,500 gm (5½lb) had a neonatal mortality rate seven times the rate for prolonged pregnancies as a whole. There was no increase in neonatal mortality among post-term infants weighing more than 4,100 gm (9 lb) compared with prolonged pregnancy infants between 2,500 and 4,100 gm (5½ to 9 lb). There was a slightly increased incidence of congenital anomalies in the prolonged gestation group. Neonatal mortality in infants with severe congenital anomalies was substantially higher in prolonged pregnancy. The excess mortality experience of prolonged pregnancy children continued for at least the first 2 years of life. Hospitalization and clinic visit data also implied a poorer health status in these children over the first 3 years of life. Data on growth and intelligence revealed no difference between children with prolonged and normal gestation in a small group examined at age 5. There were no gross placental findings to support the hypothesis of placental senility as a cause of pathology in prolonged pregnancies. A tendency was noted for prolonged pregnancy to recur in successive gestations.

scholarly journals Trends and characteristics of fetal and neonatal mortality due to congenital anomalies, Colombia 1999–2008

2017 ◽  
Vol 31 (13) ◽  
pp. 1748-1755 ◽  
Author(s):  
Claudia Patricia Roncancio ◽  
Sandra Patricia Misnaza ◽  
Isabel Cristina Peña ◽  
Franklyn Edwin Prieto ◽  
Michael J. Cannon ◽  
...  
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies

scholarly journals Prevalence of clinically-evident congenital anomalies in the Western highlands of Guatemala

2020 ◽  
Vol 17 (S2) ◽  
Author(s):  
Lester Figueroa ◽  
Ana Garces ◽  
K. Michael Hambidge ◽  
Elizabeth M. McClure ◽  
Janet Moore ◽  
...  
Keyword(s):  
Congenital Anomaly ◽  
Nervous System ◽  
Neonatal Mortality ◽  
Congenital Anomalies ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Survival Rates ◽  
Population Based ◽  
Global Network ◽  
Icd 10

Abstract Background Congenital anomalies are a significant cause of death and disability for infants, especially in low and middle-income countries (LMIC), where 95% of all deaths due to anomalies occur. Limited data on the prevalence and survival of infants with congenital anomalies are available from Central America. Estimates have indicated that 53 of every 10,000 live births in Guatemala are associated with a congenital anomaly. We aim to report on the incidence and survival of infants with congenital anomalies from a population-based registry and classify the anomalies according to the International Classification of Disease, Tenth Revision (ICD-10). Methods We conducted a planned secondary analysis of data from the Maternal Newborn Health Registry (MNHR), a prospective, population-based study carried out by the Global Network for Women’s and Children’s Health Research in seven research sites. We included all deliveries between 2014 and 2018 in urban and rural settings in Chimaltenango, in the Western Highlands of Guatemala. These cases of clinically evident anomalies were reported by field staff and reviewed by medically trained staff, who classified them according to ICD – 10 categories. The incidence of congenital anomalies and associated stillbirth, neonatal mortality, and survival rates were determined for up to 42 days. Results Out of 60,142 births, 384 infants were found to have a clinically evident congenital anomaly (63.8 per 10,000 births). The most common were anomalies of the nervous system (28.8 per 10,000), malformations and deformations of the musculoskeletal system (10.8 per 10,000), and cleft lip and palate (10.0 per 10,000). Infants born with nervous system anomalies had the highest stillbirth and neonatal mortality rates (14.6 and 9.0 per 10,000, respectively). Conclusions This is the first population-based report on congenital anomalies in Guatemala. The rates we found of overall anomalies are higher than previously reported estimates. These data will be useful to increase the focus on congenital anomalies and hopefully increase the use of interventions of proven benefit. Trial registration ClinalTrial.gov ID: NCT01073475.

Sign in / Sign up

Export Citation Format

Share Document