Lethal Congenital Anomalies as a Cause of Birth-Weight—Specific Neonatal Mortality

JAMA ◽  
1983 ◽  
Vol 250 (4) ◽  
pp. 513 ◽  
Author(s):  
Robert L. Goldenberg
Keyword(s):  
Birth Weight ◽  
Neonatal Mortality ◽  
Congenital Anomalies

Changes in Infant Morbidity Associated with Decreases in Neonatal Mortality

PEDIATRICS ◽  
1983 ◽  
Vol 72 (3) ◽  
pp. 408-415
Author(s):  
Sam Shapiro ◽  
Marie C. McCormick ◽  
Barbara H. Starfield ◽  
Barbara Crawley
Keyword(s):  
Birth Weight ◽  
Developmental Delay ◽  
Neonatal Mortality ◽  
High Mortality ◽  
Congenital Anomalies ◽  
Mortality And Morbidity ◽  
Random Samples ◽  
Infant Morbidity

Neonatal mortality and morbidity among infants surviving to 1 year of age in eight geographic areas have been compared to determine whether recent decreases in mortality have affected the risk of infants having congenital anomalies or developmental delay. Mortality was obtained from birth and death records in 1976 and either 1978 or 1979; morbidity through home interviews with mothers of random samples of infants and developmental observations on the children. It is concluded that the decrease in mortality was not offset by increases in children with defects. Neonatal mortality decreased by 18% in this 2- to 3-year period; risk of congenital anomalies or developmental delay (all types combined) declined by 16% among the surviving infants. The reduction in risk was concentrated in the minor congenital anomalies or developmental delay category; the proportion of children with severe or moderate congenital anomalies or developmental delay did not change. Decreases occurred at every birth weight including the very low birth weights of 1,500 g or less, a subgroup with especially high mortality and morbidity resulting from perinatal events.

CAUSES OF NEONATAL MORTALITY IN SPAIN (1975–98): INFLUENCE OF SEX, RURAL–URBAN RESIDENCE AND AGE AT DEATH

2005 ◽  
Vol 38 (4) ◽  
pp. 537-551 ◽  
Author(s):  
VERÓNICA ALONSO ◽  
VICENTE FUSTER ◽  
FRANCISCO LUNA
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Mortality ◽  
Congenital Anomalies ◽  
Urban Areas ◽  
Age At Death ◽  
Male Mortality ◽  
Respiratory Problems ◽  
Early Neonatal Mortality ◽  
Preterm Born

Neonatal mortality during the first week of life, corresponding to the years 1975–1998, was studied in Spain. The first week of life is the time in which the highest number of deaths occur. The temporal decrease of the neonatal mortality rate (NMR) was modelled according to log10(NMR+1)= 2·784−0·023 per year. This decline cannot be explained by an increase in the mean birth weight (MBW=23440·835−10·107 g per year). From the most frequent of the causes of death to the least were: congenital anomalies, preterm born or low birth weight, respiratory problems, pregnancy difficulties, hypoxaemia/asphyxia, delivery difficulties and infectious diseases. This sequence changed when the specific age at death was considered. The NMR descended evenly for both sexes for the causes indicated above, except for preterm born or low birth weight, in which the male mortality decrease was greater since its rate was more elevated at the beginning of the period studied. For all the causes listed, NMR was more elevated both in urban areas and for males. Early neonatal mortality (first 24 hours) was higher for pregnancy difficulties, preterm born or low birth weight, congenital anomalies and hypoxaemia/asphyxia.

scholarly journals Geospatial analysis of determinants of neonatal mortality in Ghana

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Duah Dwomoh
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Mortality ◽  
Neonatal Death ◽  
Reproductive Age ◽  
Multiple Births ◽  
Demographic And Health Surveys ◽  
Neonatal Deaths ◽  
The Impact

Abstract Background Ghana did not meet the Millennium Development Goal 4 of reducing child mortality by two-thirds and may not meet SDG (2030). There is a need to direct scarce resources to mitigate the impact of the most important risk factors influencing high neonatal deaths. This study applied both spatial and non-spatial regression models to explore the differential impact of environmental, maternal, and child associated risk factors on neonatal deaths in Ghana. Methods The study relied on data from the Ghana Demographic and Health Surveys (GDHS) and the Ghana Maternal Health Survey (GMHS) conducted between 1998 and 2017 among 49,908 women of reproductive age and 31,367 children under five (GDHS-1998 = 3298, GDHS-2003 = 3844, GDHS-2008 = 2992, GDHS-2014 = 5884, GMHS-2017 = 15,349). Spatial Autoregressive Models that account for spatial autocorrelation in the data at the cluster-level and non-spatial statistical models with appropriate sampling weight adjustment were used to study factors associated with neonatal deaths, and a p-value less than 0.05 was considered statistically significant. Results Population density, multiple births, smaller household sizes, high parity, and low birth weight significantly increased the risk of neonatal deaths over the years. Among mothers who had multiple births, the risk of having neonatal deaths was approximately four times as high as the risk of neonatal deaths among mothers who had only single birth [aRR = 3.42, 95% CI: 1.63–7.17, p < 0.05]. Neonates who were perceived by their mothers to be small were at a higher risk of neonatal death compared to very large neonates [aRR = 2.08, 95% CI: 1.19–3.63, p < 0.05]. A unit increase in the number of children born to a woman of reproductive age was associated with a 49% increased risk in neonatal deaths [aRR = 1.49, 95% CI: 1.30–1.69, p < 0.05]. Conclusion Neonatal mortality in Ghana remains relatively high, and the factors that predisposed children to neonatal death were birth size that were perceived to be small, low birth weight, higher parity, and multiple births. Improving pregnant women’s nutritional patterns and providing special support to women who have multiple deliveries will reduce neonatal mortality in Ghana.

Leminorella sepsis in very low birth weight neonate as cause of neonatal mortality

2016 ◽  
Vol 30 (9) ◽  
pp. 1057-1059 ◽  
Author(s):  
Deepak Sharma ◽  
Ankur Patel ◽  
Priyanka Soni ◽  
Sweta Shastri ◽  
Ravinder Singh
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Mortality ◽  
Very Low Birth Weight ◽  
Birth Weight Neonate

scholarly journals Investigation of Metronidazole Use during Pregnancy and Adverse Birth Outcomes

2012 ◽  
Vol 56 (9) ◽  
pp. 4800-4805 ◽  
Author(s):  
Catherine A. Koss ◽  
Dana C. Baras ◽  
Sandra D. Lane ◽  
Richard Aubry ◽  
Michele Marcus ◽  
...  
Keyword(s):  
New York ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Congenital Anomalies ◽  
New York State ◽  
Multivariable Analysis ◽  
Preterm Births ◽  
First Trimester ◽  
First Trimester Of Pregnancy

ABSTRACTTo assess whether treatment with metronidazole during pregnancy is associated with preterm birth, low birth weight, or major congenital anomalies, we conducted chart reviews and an analysis of electronic data from a cohort of women delivering at an urban New York State hospital. Of 2,829 singleton/mother pairs, 922 (32.6%) mothers were treated with metronidazole for clinical indications, 348 (12.3%) during the first trimester of pregnancy and 553 (19.5%) in the second or third trimester. There were 333 (11.8%) preterm births, 262 (9.3%) infants of low birth weight, and 52 infants (1.8%) with congenital anomalies. In multivariable analysis, no association was found between metronidazole treatment and preterm birth (odds ratio [OR], 1.02 [95% confidence interval [CI], 0.80 to 1.32]), low birth weight (OR, 1.05 [95% CI, 0.77 to 1.43]), or treatment in the first trimester and congenital anomalies (OR, 0.86 [0.30 to 2.45]). We found no association between metronidazole treatment during the first or later trimesters of pregnancy and preterm birth, low birth weight, or congenital anomalies.

Contribution of Congenital Anomalies to Neonatal Mortality Rates in Malta

2015 ◽  
Vol 29 (5) ◽  
pp. 401-406 ◽  
Author(s):  
Miriam Gatt ◽  
Kathleen England ◽  
Victor Grech ◽  
Neville Calleja
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies ◽  
Mortality Rates

Understanding the relative contributions of prematurity and congenital anomalies to neonatal mortality

2022 ◽  
Author(s):  
Ciaran S. Phibbs ◽  
Molly Passarella ◽  
Susan K. Schmitt ◽  
Jeannette A. Rogowski ◽  
Scott A. Lorch
Keyword(s):  
Neonatal Mortality ◽  
Congenital Anomalies

IMPACT OF NEONATAL INTENSIVE CARE

PEDIATRICS ◽  
1996 ◽  
Vol 97 (2) ◽  
pp. 215-215
Author(s):  
Student
Keyword(s):  
Intensive Care ◽  
Birth Weight ◽  
Mortality Rate ◽  
Neonatal Mortality ◽  
Neonatal Intensive Care ◽  
Neonatal Mortality Rate ◽  
Total Reduction ◽  
Weight Groups

Neonates who weighed &gt; 1.5 kg at birth were the major contributors to the overall reduction in the neonatal mortality rate (NMR); approximately two thirds of total reduction in the NMR between 1960 and 1980 and 52.6% of the total reduction between 1980 and 1986 occurred in the &gt; 1.5-kg birth weight groups.

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