Correction: How do women experience a false-positive test result from breast screening? A systematic review and thematic synthesis of qualitative studies

The interferon-γ assay has been used worldwide as an ancillary test for the diagnosis of bovine tuberculosis (bTB). This study aimed to describe, based on the bTB-free status in Switzerland, the difference of applying a more stringent cutoff point of 0.05 compared with 0.1 for bTB surveillance. Moreover, the effect of time between blood collection and stimulation, culture results, optical density values, and the influence of testing different breeds were evaluated. Blood samples from a total of 118 healthy cows older than 6 months were tested with three commercial interferon-gamma assays. To confirm the bTB-free status of the tested animals and to investigate potential cross-reactions with nontuberculous mycobacteria, pulmonary and abdominal lymph nodes in addition to ileal mucosa from each cattle were used for the detection of viable Mycobacteria spp. by specific culture. Significant differences regarding the proportion of false-positive results between the two Bovigam tests and between Bovigam 2G and ID Screen were found. Samples analyzed with Bovigam 2G were 2.5 [95% confidence interval (CI) 1.6–3.9] times more likely to yield a false-positive test result than samples analyzed with Bovigam TB. Similarly, the odds ratio (OR) for testing samples false-positive with ID Screen compared with Bovigam TB was 1.9 (95% CI 1.21–2.9). The OR for testing false-positive with ID Screen compared with Bovigam 2G was less to equally likely with an OR of 0.75 (95% CI 0.5–1.1). When using a cutoff of 0.05 instead of 0.1, the OR for a false-positive test result was 2.2 (95% CI 1.6–3.1). Samples tested after 6 h compared with a delayed stimulation time of 22–24 h were more likely to yield a false-positive test result with an OR of 3.9 (95% CI 2.7–5.6). In conclusion, applying a more stringent cutoff of 0.05 with the Bovigam 2G kit generates a questionable high number of false-positive results of one of three tested animals. Furthermore, specific breeds might show an increased risk to result false-positive in the Bovigam 2G and the ID Screen assays.

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A Positive Attitude to Negate a False Positive Test Result: An Intern’s Experience with COVID-19

International Journal of Medical Students ◽

10.5195/ijms.2020.526 ◽

2020 ◽

Author(s):

Vanessa N. Youmbi

Keyword(s):

False Positive ◽

Positive Attitude ◽

Democratic Republic ◽

Democratic Republic Of Congo ◽

Positive Test ◽

Psychological Interventions ◽

Test Results ◽

Positive Test Result ◽

False Positive Test ◽

Test Result

I recount my experience as an intern in the Democratic Republic of Congo during the COVID-19 pandemic. I received a patient who was presumed to have COVID and was isolated. The first test result was a false positive, so I was discharged. Although I was not infected by COVID-19, I was adversely affected by it. The anxiety of waiting for test results and isolation are both mentally challenging. Also, COVID-related stigmatization is a serious complication of the disease. Targeted psychological interventions should prevent all three.

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Absence of risk factors for false-positive test results inblood donors with a reactive test result inan automated treponemal test (PK-TP) for syphilis

Transfusion ◽

10.1046/j.1537-2995.2001.41060744.x ◽

2001 ◽

Vol 41 (6) ◽

pp. 744-750 ◽

Cited By ~ 11

Author(s):

Sharyn L. Orton ◽

Roger Y. Dodd ◽

Alan E. Williams ◽

Keyword(s):

Risk Factors ◽

False Positive ◽

Positive Test ◽

Test Results ◽

False Positive Test ◽

Test Result

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S1127 Participants in a Colorectal Cancer Screening Program Having a False Positive Test Result, Experience Adverse Psychological Symptoms up to 6 Weeks After the Colonoscopy

Gastroenterology ◽

10.1016/s0016-5085(10)60843-8 ◽

2010 ◽

Vol 138 (5) ◽

pp. S-186

Author(s):

Maaike Denters ◽

Marije Deutekom ◽

Marie-Louise Essink-Bot ◽

Patrick M. Bossuyt ◽

Paul Fockens ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Screening ◽

Colorectal Cancer Screening ◽

False Positive ◽

Psychological Symptoms ◽

Screening Program ◽

Positive Test Result ◽

False Positive Test ◽

Cancer Screening Program ◽

Test Result

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Internal Impingement of the Shoulder: A Risk of False Positive Test Outcomes in External Impingement Tests?

BioMed Research International ◽

10.1155/2017/2941238 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

Tim Leschinger ◽

Christopher Wallraff ◽

Dirk Müller ◽

Matthias Hackenbroch ◽

Henning Bovenschulte ◽

...

Keyword(s):

Positive Test ◽

Positive Test Result ◽

Mechanical Contact ◽

Open Mri ◽

Pathologic Condition ◽

Shoulder Impingement ◽

Internal Impingement ◽

False Positive Test ◽

Test Outcomes ◽

Test Result

Background. External impingement tests are considered as being particularly reliable for identifying subacromial and coracoid shoulder impingement mechanisms. The purpose of the present study was to evaluate if these tests are likely to provoke an internal shoulder impingement mechanism which, in cases of a pathologic condition, can lead to a positive test result.Method. In 37 subjects, the mechanical contact between the glenoid rim and the rotator cuff (RC) was measured quantitatively and qualitatively in external impingement test positions using an open MRI system.Results. Mechanical contact of the supraspinatus with the posterosuperior glenoid was present in 30 subjects in the Neer test. In the Hawkins test, the subscapularis was in contact with the anterosuperior glenoid in 33 subjects and the supraspinatus in 18. In the horizontal impingement test, anterosuperior contact of the supraspinatus with the glenoid was identified in 35 subjects.Conclusion. The Neer, Hawkins, and horizontal impingement tests are likely to provoke the mechanism of an internal shoulder impingement. A posterosuperior internal impingement mechanism is being provoked predominately in the Neer test. The Hawkins test narrows the distance between the insertions of the subscapularis and supraspinatus and the anterosuperior labrum, which leads to an anterosuperior impingement mechanism.

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