Serum uric acid level is associated with an increase in systolic blood pressure over time in female subjects: Linear mixed-effects model analyses

2021 ◽  
Author(s):  
Kazuma Mori ◽  
Masato Furuhashi ◽  
Marenao Tanaka ◽  
Yukimura Higashiura ◽  
Masayuki Koyama ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Systolic Blood Pressure ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Mixed Effects ◽  
Linear Mixed Effects Model ◽  
Linear Mixed Effects ◽  
Over Time

scholarly journals Association of Serum Uric Acid Level With Blood Pressure Variability in Newly Diagnosed Essential Hypertension

2015 ◽  
Vol 17 (12) ◽  
pp. 929-935 ◽  
Author(s):  
Kumral Çağlı ◽  
Osman Turak ◽  
Uğur Canpolat ◽  
Fırat Özcan ◽  
Derya Tok ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Essential Hypertension ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Blood Pressure Variability ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Newly Diagnosed

scholarly journals Relationship Between Uric Acid Level and Blood Pressure in T2DM Patient Attending in BIRDEM General Hospital

2018 ◽  
Vol 9 (2) ◽  
pp. 49-53
Author(s):  
S Ferdous ◽  
K Begum ◽  
MA Muttalib
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Stone Formation ◽  
Serum Uric Acid Level ◽  
High Serum ◽  
Normal Serum ◽  
Significant Difference

Hyperuricemia is associated with higher mortality in patients suffering from hypertension, coronary heart disease, cerebrovascular events, metabolic syndrome, insulin resistance, gout and renal stone formation and it is more in individuals with diabetes. The prevalence of hyperuricemia is high in T2DM. The aim of the present study was to assess the relationship between hyperuricemia and blood pressure in T2DM subjects and thus to help the clinician for early diagnosis, treatment and to prevent further complications. Total 350 study subjects were enrolled for this study; among them 203 were T2DM with normal level of serum uric acid level and 147 were T2DM with high serum uric acid level. It was observed that systolic blood pressure was significantly higher (134.5±9.6 mm of Hg) in T2DM with hyperuricemia (p<0.001) than T2DM with normal serum uric acid level (123.3±10.9 mm of Hg). On the other hand diastolic blood pressure was significantly higher (87.1±5.9 mm of Hg) in T2DM with hyperuricemia (p<0.001) than T2DM with normal serum uric acid level (79.6±8.3 mm of Hg). Age (years) showed no significant difference between T2DM with serum uric acid<7 mg/dl and T2DM with serum uric acid>7 mg/dl (p<0.05). In our study it was revealed that males were in greater risk of developing hyperuricemia. BMI was significantly (p<0.001) greater in T2DM subjects who had normal serum uric acid level (27.9±3.8) than with those who had serum uric acid>7 mg/dl (24.4±3.83). No significant differences were found in FBS, blood sugar 2 hours after breakfast, HbA1C, serum creatinine and blood urea between groups.Bangladesh J Med Biochem 2016; 9(2): 49-53

scholarly journals ESSENTIAL HYPERTENSION

2015 ◽  
Vol 22 (07) ◽  
pp. 854-858
Author(s):  
Muhammad Iqbal Shah ◽  
Ramesh Kumar Suthar ◽  
Mukhtiar Ahmed Soomro
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Essential Hypertension ◽  
Serum Uric Acid ◽  
High Blood Pressure ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
High Serum ◽  
Research Studies

Background: Little and sparse information is present in our population onassociation between serum uric acid and essential hypertension .Increased serum uric acid isrelated with elevated blood pressure in different research studies. The relationship betweenserum uric acid level and high blood pressure can be difficult to assess because drugs for highblood pressure usually affect uric acid level. Objectives: The objective of our study is to evaluatethe association of serum uric acid to severity and duration of essential hypertension at LiaquatUniversity Hospital (tertiary care) Hyderabad / Jamshoro Methodology: Study Design: Casecontrol and prospective study. Setting: Medical wards and Out Patient Medicine Department ofLiaquat University Hospital Hyderabad / Jamshoro. Period: One year i.e. from 20th March 2013to 19th February 2014. Methodology: A total of 75 high blood pressure subjects aged 35 yearsand above were included as cases with same number(75) of age & sex matched normal bloodpressure subjects as controls after excluding, Secondary hypertension, metabolic syndrome,Diabetes Mellitus, age <40 ;>70 years, hypothyroidism, hyperparathyroidism, Ischemic heartdisease, congestive cardiac failure,Alcohol abuse, Renal Insufficiency, glomerulonephritis,pyelonephritis, hereditary nephropathy, patients on drugs –, ethambutol,levodopa pyrazinamide,low dose asprin, Cytotoxic drugs, nicotinic acid ,thiazide diuretics.. Qualitative and quantitativedata were evaluated in SPSS version 16.0. Results: The mean serum uric acid level was 6.3± 1.4 mg/dl vs 4.5 ± 1.2 mg/dl in case (n = 75) and control patients (n = 75) respectively. Atotal of 23 (30.6%, n = 75) patients in cases and 8 (10.6%) subjects in control had high serumuric acid (Odds Ratio 2.13, p <0.05). Therefore, the frequency of increased serum uric acidlevel subjects & mean serum uric acid level were significantly greater in hypertensive cases,as compared to those of healthy normal blood pressure Controls. Serum uric acid correlatedpositively with both systolic blood pressure (r=0.132, p<0.01) and diastolic blood pressure(r=0.214; p<0.01). Conclusion: High serum uric acid is frequent in our populace with essentialhypertension and there is relationship between serum uric acid level and blood pressure.Further large scale research studies on the pathophysiologic significance of high serum uricacid in these high blood pressure patients are in further need.

scholarly journals Serum uric acid level, blood pressure, and vascular angiotensin II responsiveness in healthy men and women

2014 ◽  
Vol 2 (12) ◽  
pp. e12235 ◽  
Author(s):  
Arian Samimi ◽  
Sharanya Ramesh ◽  
Tanvir C. Turin ◽  
Jennifer M. MacRae ◽  
Magdalena A. Sarna ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Angiotensin Ii ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Men And Women ◽  
Healthy Men

scholarly journals Serum Uric Acid Level, Longitudinal Blood Pressure, Renal Function, and Long-Term Mortality in Treated Hypertensive Patients

Hypertension ◽  
2013 ◽  
Vol 62 (1) ◽  
pp. 105-111 ◽  
Author(s):  
Jesse Dawson ◽  
Panniyammakal Jeemon ◽  
Lucy Hetherington ◽  
Caitlin Judd ◽  
Claire Hastie ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Hypertensive Patients ◽  
Long Term Mortality

scholarly journals HUBUNGAN ANTARA KADAR ASAM URAT DENGAN TEKANAN DARAH PADA MAHASISWA PRIA OBESITAS SENTRAL FAKULTAS KEDOKTERAN UNIVERSITAS SAM RATULANGI MANADO

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Siti N. Mansur ◽  
Frans E. Wantania ◽  
Eko Surachmanto
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Uric Acid Level ◽  
Acid Level ◽  
Pearson Correlation ◽  
Male Students ◽  
Waist Size ◽  
The Mean

Abstract: Inflammation plays an important role in hypertension process and central obesity. Recent studies found that hyperuricemia was also related to inflammation. This study aimed to find out the relation between uric acid level with blood pressure among central-obese-male students in the Faculty of Medicine Unsrat. Methods: This was an analytical study with a cross section design. There were 37 people as samples. Data were obtained by measuring the waist size, blood pressure, and uric acid. The data were analyzed with the Statistical Product and Service Solution (SPSS) and Pearson correlation test. The results showed that most respondents were 19 years old (12 respondents, 32.4%) and the lowest were 17, 22 and 23 years old, each of them was 1 person (2.7%). The mean systolic blood pressure was 130.54 mmHg (SD ± 10.259). The mean diastolic blood pressure was 88.11 mmHg (SD ± 7.760). The mean level of uric acid was 7.514 mg/dL (SD ± 1.65). This study showed that there was some significant relation between the systolic blood pressure and uric acid level (p=0.019), as well as between the diastolic blood pressure and uric acid level (p=0.022). Conclusion: There was a significant correlation between the uric acid level and blood pressure in male students with central obesity.Keywords: obesity, uric acid, blood pressureAbstrak: Inflamasi berperan penting dalam proses terjadinya hipertensi dan obesitas sentral. Pada penelitian terkini ditemukan bahwa hiperurisemia juga berhubungan dengan proses inflamasi. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar asam urat dengan tekanan darah pada mahasiswa pria obesitas sentral Fakultas Kedokteran Unsrat. Penelitian ini bersifat analitik menggunakan rancangan potong lintang dengan sampel berjumlah 37 orang. Data diperoleh melalui pemeriksaan lingkar perut, tekanan darah, dan asam urat. Data dianalisis dengan menggunakan Statistical Product and Service Solution (SPSS) dan uji Pearson correlation. Hasil penelitian memperlihatkan bahwa sebagian besar responden berada pada kategori umur 19 tahun (12 responden, 32,4%) dan terendah umur 17, 22, dan 23 tahun masing-masing sejumlah 1 orang (2,7%). Berdasarkan nilai mean dapat dilihat bahwa rerata tekanan darah sistol 130,54 mmHg (SD ± 10,259). Rerata tekanan darah diastol 88,11 mmHg (SD ± 7,760). Rerata kadar asam urat responden 7,514 mg/dL (SD ± 1,65). Hasil penelitian menunjukkan secara statistik terdapat hubungan yang bermakna, baik antara tekanan darah sistol dan asam urat (p=0,019) maupun antara tekanan darah diastol dan kadar asam urat (p=0,022). Simpulan: Terdapat hubungan bermakna antara kadar asam urat dan tekanan darah pada mahasiswa pria obesitas sentral.Kata kunci: obesitas, asam urat, tekanan darah

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