scholarly journals Swarm Learning for decentralized and confidential clinical machine learning

Nature ◽  
2021 ◽  
Author(s):  
Stefanie Warnat-Herresthal ◽  
◽  
Hartmut Schultze ◽  
Krishnaprasad Lingadahalli Shastry ◽  
Sathyanarayanan Manamohan ◽  
...  
Keyword(s):  
Machine Learning ◽  
Precision Medicine ◽  
Distributed Data ◽  
X Ray ◽  
Uniform Distributions ◽  
Privacy Laws ◽  
Data Owner ◽  
Machine Learning Approach ◽  
Chest X Ray ◽  
Privacy Legislation

AbstractFast and reliable detection of patients with severe and heterogeneous illnesses is a major goal of precision medicine1,2. Patients with leukaemia can be identified using machine learning on the basis of their blood transcriptomes3. However, there is an increasing divide between what is technically possible and what is allowed, because of privacy legislation4,5. Here, to facilitate the integration of any medical data from any data owner worldwide without violating privacy laws, we introduce Swarm Learning—a decentralized machine-learning approach that unites edge computing, blockchain-based peer-to-peer networking and coordination while maintaining confidentiality without the need for a central coordinator, thereby going beyond federated learning. To illustrate the feasibility of using Swarm Learning to develop disease classifiers using distributed data, we chose four use cases of heterogeneous diseases (COVID-19, tuberculosis, leukaemia and lung pathologies). With more than 16,400 blood transcriptomes derived from 127 clinical studies with non-uniform distributions of cases and controls and substantial study biases, as well as more than 95,000 chest X-ray images, we show that Swarm Learning classifiers outperform those developed at individual sites. In addition, Swarm Learning completely fulfils local confidentiality regulations by design. We believe that this approach will notably accelerate the introduction of precision medicine.

scholarly journals Swarm Learning as a privacy-preserving machine learning approach for disease classification

2020 ◽  
Author(s):  
Stefanie Warnat-Herresthal ◽  
Hartmut Schultze ◽  
Krishnaprasad Lingadahalli Shastry ◽  
Sathyanarayanan Manamohan ◽  
Saikat Mukherjee ◽  
...  
Keyword(s):  
Machine Learning ◽  
Precision Medicine ◽  
Disease Classification ◽  
Learning Approach ◽  
Distributed Data ◽  
Privacy Laws ◽  
Data Owner ◽  
Machine Learning Approach ◽  
Life Threatening ◽  
Privacy Legislation

AbstractIdentification of patients with life-threatening diseases including leukemias or infections such as tuberculosis and COVID-19 is an important goal of precision medicine. We recently illustrated that leukemia patients are identified by machine learning (ML) based on their blood transcriptomes. However, there is an increasing divide between what is technically possible and what is allowed because of privacy legislation. To facilitate integration of any omics data from any data owner world-wide without violating privacy laws, we here introduce Swarm Learning (SL), a decentralized machine learning approach uniting edge computing, blockchain-based peer-to-peer networking and coordination as well as privacy protection without the need for a central coordinator thereby going beyond federated learning. Using more than 14,000 blood transcriptomes derived from over 100 individual studies with non-uniform distribution of cases and controls and significant study biases, we illustrate the feasibility of SL to develop disease classifiers based on distributed data for COVID-19, tuberculosis or leukemias that outperform those developed at individual sites. Still, SL completely protects local privacy regulations by design. We propose this approach to noticeably accelerate the introduction of precision medicine.

scholarly journals A Prediction of Corona Disease Transmission Using A Traditional Machine Learning Approach

2020 ◽  
pp. 447-452
Author(s):  
Chandran Venkatesan ◽  
Elakkiya Balan ◽  
Sumithra M G ◽  
Karthick A ◽  
Jayarajan V ◽  
...  
Keyword(s):  
Machine Learning ◽  
Disease Transmission ◽  
Transition Process ◽  
Machine Learning Algorithms ◽  
Learning Approach ◽  
X Ray ◽  
Machine Learning Approach ◽  
Current Scenario ◽  
Chest X Ray ◽  
Bayes Algorithm

In this current scenario, covid pandemic breaks analysis is becoming popular among the researchers. The various data sources from the different countries analyzed to predict the possibility of coronavirus transition from one person to another person. The datasets are not providing more information about the causes of the corona. Many authors provided the solution by using chest X-ray and CT images to predict the corona. In this paper, the covid pandemic transition process from one person to another person was classified using traditional machine learning algorithms. The input labels are encoded and transformed, utilizing the label encoder technique. The XG boost algorithm was outperformed all the other algorithms with overall accuracy and F1-measure of 99%. The Naive Bayes algorithm provides 100% accuracy, precision, recall, and F1-Score due to its improved ability to handle lower datasets.

scholarly journals Machine Learning Approach using CNN for COVID-19 Pandemic Detection

2021 ◽  
Vol 11 (2) ◽  
pp. 63-67
Author(s):  
Dr. Vikas S ◽  
◽  
Dr. Thimmaraju S N ◽  
Keyword(s):  
Infectious Disease ◽  
Machine Learning ◽  
Data Science ◽  
Corrective Action ◽  
Learning Approach ◽  
Data Generation ◽  
X Ray ◽  
Domain Names ◽  
Machine Learning Approach ◽  
Chest X Ray

Data science and machine learning are domain names in which data generation can assist with inside the fight towards the disease. Early caution systems which can are expecting how much a disease might effect society and permit the authorities to take suitable measures without disrupting the economy are extremely important. In the confrontation towards COVID-19 methods for forecasting the future cases primarily based totally on present data are extremely beneficial. The preceding are three strategies of machine learning which are discussed: Two for predicting the wide variety of positive cases in the coming ten days, and one for identifying COVID-19 infection via way of means of analyzing the patient's chest x-ray image. Various algorithms had been tested, and the only that produced the maximum accurate consequences become selected for use on this take a look at to forecast confirmed cases in India. Various government entities can leverage the findings to take corrective action. Now that methods for forecasting infectious disease are available, COVID-19 can be less complicated to combat.

scholarly journals An Integrated Framework with Machine Learning and Radiomics for Accurate and Rapid Early Diagnosis of COVID-19 from Chest X-ray

2021 ◽  
pp. 115152
Author(s):  
Mahbubunnabi Tamal ◽  
Maha Alshammari ◽  
Meernah Alabdullah ◽  
Rana Hourani ◽  
Hossain Abu Alola ◽  
...  
Keyword(s):  
Machine Learning ◽  
Early Diagnosis ◽  
X Ray ◽  
Integrated Framework ◽  
Chest X Ray

scholarly journals A Machine Learning Approach For Classifying Low-mass X-ray Binaries Based On Their Compact Object Nature

2020 ◽  
Author(s):  
R Pattnaik ◽  
K Sharma ◽  
K Alabarta ◽  
D Altamirano ◽  
M Chakraborty ◽  
...  
Keyword(s):  
Machine Learning ◽  
Black Hole ◽  
Neutron Star ◽  
Binary Systems ◽  
Compact Object ◽  
X Ray ◽  
Average Accuracy ◽  
Machine Learning Approach ◽  
Low Mass ◽  
X Ray Binaries

Abstract Low Mass X-ray binaries (LMXBs) are binary systems where one of the components is either a black hole or a neutron star and the other is a less massive star. It is challenging to unambiguously determine whether a LMXB hosts a black hole or a neutron star. In the last few decades, multiple observational works have tried, with different levels of success, to address this problem. In this paper, we explore the use of machine learning to tackle this observational challenge. We train a random forest classifier to identify the type of compact object using the energy spectrum in the energy range 5-25 keV obtained from the Rossi X-ray Timing Explorer archive. We report an average accuracy of 87±13% in classifying the spectra of LMXB sources. We further use the trained model for predicting the classes for LMXB systems with unknown or ambiguous classification. With the ever-increasing volume of astronomical data in the X-ray domain from present and upcoming missions (e.g., SWIFT, XMM-Newton, XARM, ATHENA, NICER), such methods can be extremely useful for faster and robust classification of X-ray sources and can also be deployed as part of the data reduction pipeline.

Chest X-Ray Image-Based Testing Using Machine Learning Techniques

Covid-19 ◽  
2021 ◽  
pp. 241-278
Author(s):  
Parag Verma ◽  
Ankur Dumka ◽  
Alaknanda Ashok ◽  
Amit Dumka ◽  
Anuj Bhardwaj
Keyword(s):  
Machine Learning ◽  
Machine Learning Techniques ◽  
X Ray ◽  
Learning Techniques ◽  
Chest X Ray

scholarly journals Detection of COVID-19 from Chest X-Ray Images Using Convolutional Neural Networks

2020 ◽  
Vol 25 (6) ◽  
pp. 553-565 ◽  
Author(s):  
Boran Sekeroglu ◽  
Ilker Ozsahin
Keyword(s):  
Machine Learning ◽  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Statistical Data ◽  
Area Under The Curve ◽  
Operating Characteristics ◽  
X Ray ◽  
Life Saving ◽  
Chest X Ray

The detection of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), which is responsible for coronavirus disease 2019 (COVID-19), using chest X-ray images has life-saving importance for both patients and doctors. In addition, in countries that are unable to purchase laboratory kits for testing, this becomes even more vital. In this study, we aimed to present the use of deep learning for the high-accuracy detection of COVID-19 using chest X-ray images. Publicly available X-ray images (1583 healthy, 4292 pneumonia, and 225 confirmed COVID-19) were used in the experiments, which involved the training of deep learning and machine learning classifiers. Thirty-eight experiments were performed using convolutional neural networks, 10 experiments were performed using five machine learning models, and 14 experiments were performed using the state-of-the-art pre-trained networks for transfer learning. Images and statistical data were considered separately in the experiments to evaluate the performances of models, and eightfold cross-validation was used. A mean sensitivity of 93.84%, mean specificity of 99.18%, mean accuracy of 98.50%, and mean receiver operating characteristics–area under the curve scores of 96.51% are achieved. A convolutional neural network without pre-processing and with minimized layers is capable of detecting COVID-19 in a limited number of, and in imbalanced, chest X-ray images.

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