scholarly journals Fatty Acid Supplementation Reverses the Small Colony Variant Phenotype in Triclosan-Adapted Staphylococcus aureus: Genetic, Proteomic and Phenotypic Analyses

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Abdulrahman S. Bazaid ◽  
Sarah Forbes ◽  
Gavin J. Humphreys ◽  
Ruth G. Ledder ◽  
Ronan O’Cualain ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Fatty Acid ◽  
Fatty Acid Supplementation ◽  
Acid Supplementation ◽  
Small Colony Variant ◽  
Variant Phenotype ◽  
Small Colony

scholarly journals Attenuated Vancomycin Bactericidal Activity against Staphylococcus aureus hemB Mutants Expressing the Small-Colony-Variant Phenotype

2008 ◽  
Vol 52 (4) ◽  
pp. 1533-1537 ◽  
Author(s):  
Brian T. Tsuji ◽  
Christof von Eiff ◽  
Pamela A. Kelchlin ◽  
Alan Forrest ◽  
Patrick F. Smith
Keyword(s):  
Staphylococcus Aureus ◽  
Bactericidal Activity ◽  
Pharmacodynamic Model ◽  
Small Colony Variant ◽  
Variant Phenotype ◽  
Small Colony ◽  
Bactericidal Activities

ABSTRACT The in vitro bactericidal activities of vancomycin against Staphylococcus aureus hemB mutants displaying the small-colony-variant phenotype and their parental strains were evaluated. Vancomycin killing activities against hemB mutants were markedly attenuated, demonstrating approximately 50% less effect, a result which was well described by a Hill-type pharmacodynamic model.

Molecular analysis of the thymidine-auxotrophic small colony variant phenotype of Staphylococcus aureus

2007 ◽  
Vol 297 (4) ◽  
pp. 217-225 ◽  
Author(s):  
Silke Besier ◽  
Albrecht Ludwig ◽  
Knut Ohlsen ◽  
Volker Brade ◽  
Thomas A. Wichelhaus
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Analysis ◽  
Small Colony Variant ◽  
Variant Phenotype ◽  
Small Colony

Identification of differentially expressed small non-protein-coding RNAs in Staphylococcus aureus displaying both the normal and the small-colony variant phenotype

2010 ◽  
Vol 88 (6) ◽  
pp. 565-575 ◽  
Author(s):  
Luay F. Abu-Qatouseh ◽  
Suresh V. Chinni ◽  
Jochen Seggewiß ◽  
Richard A. Proctor ◽  
Jürgen Brosius ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Differentially Expressed ◽  
Protein Coding ◽  
Small Colony Variant ◽  
Variant Phenotype ◽  
Small Colony
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