Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein

Scientific Reports ◽

10.1038/s41598-020-61928-w ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Alexander W. Boyden ◽

Ashley A. Brate ◽

Nitin J. Karandikar

Keyword(s):

Multiple Sclerosis ◽

B Cell ◽

Proteolipid Protein ◽

Myelin Proteolipid Protein ◽

Extracellular Domains ◽

Myelin Proteolipid ◽

Multiple Sclerosis Model

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The immune response to myelin proteolipid protein in the Lewis rat: identification of the immunodominant B cell epitope

Journal of Neuroimmunology ◽

10.1016/0165-5728(90)90065-u ◽

1990 ◽

Vol 27 (2-3) ◽

pp. 155-162 ◽

Author(s):

C.A. Gunn ◽

M.K. Richards ◽

C. Linington

Keyword(s):

Immune Response ◽

B Cell ◽

Cell Epitope ◽

Proteolipid Protein ◽

Lewis Rat ◽

Myelin Proteolipid Protein ◽

B Cell Epitope ◽

Myelin Proteolipid

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Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis Than in Healthy Subjects

The Journal of Immunology ◽

10.4049/jimmunol.165.9.5322 ◽

2000 ◽

Vol 165 (9) ◽

pp. 5322-5331 ◽

Author(s):

Michael P. Pender ◽

Peter A. Csurhes ◽

Judith M. Greer ◽

Paul D. Mowat ◽

Robert D. Henderson ◽

...

Keyword(s):

Multiple Sclerosis ◽

T Cell ◽

Healthy Subjects ◽

Proteolipid Protein ◽

Cell Reactivity ◽

Myelin Proteolipid Protein ◽

T Cell Reactivity ◽

Myelin Proteolipid

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Effect of gender on T-cell proliferative responses to myelin proteolipid protein antigens in patients with multiple sclerosis and controls

Journal of Autoimmunity ◽

10.1016/j.jaut.2004.03.004 ◽

2004 ◽

Vol 22 (4) ◽

pp. 345-352 ◽

Author(s):

Judith M. Greer ◽

Peter A. Csurhes ◽

Michael P. Pender ◽

Pamela A. McCombe

Keyword(s):

Multiple Sclerosis ◽

T Cell ◽

Proteolipid Protein ◽

Protein Antigens ◽

Myelin Proteolipid Protein ◽

Myelin Proteolipid

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T cell recognition of myelin proteolipid protein and myelin proteolipid protein peptides in the peripheral blood of multiple sclerosis and control subjects

Journal of Neuroimmunology ◽

10.1016/s0165-5728(97)00260-9 ◽

1998 ◽

Vol 84 (2) ◽

pp. 172-178 ◽

Author(s):

John L Trotter ◽

Clara M Pelfrey ◽

Amy L Trotter ◽

Jacqueline A Selvidge ◽

Kelly C Gushleff ◽

...

Keyword(s):

Multiple Sclerosis ◽

T Cell ◽

Peripheral Blood ◽

Proteolipid Protein ◽

Cell Recognition ◽

Myelin Proteolipid Protein ◽

T Cell Recognition ◽

Control Subjects ◽

And Control ◽

Myelin Proteolipid

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Myelin proteolipid protein: An effective autoantigen and target of autoimmunity in multiple sclerosis

Journal of Autoimmunity ◽

10.1016/j.jaut.2008.04.018 ◽

2008 ◽

Vol 31 (3) ◽

pp. 281-287 ◽

Author(s):

Judith M. Greer ◽

Michael P. Pender

Keyword(s):

Multiple Sclerosis ◽

Proteolipid Protein ◽

Myelin Proteolipid Protein ◽

Myelin Proteolipid

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Increased immunoreactivity to two overlapping peptides of myelin proteolipid protein in multiple sclerosis

Brain ◽

10.1093/brain/120.8.1447 ◽

1997 ◽

Vol 120 (8) ◽

pp. 1447-1460 ◽

Author(s):

J. Greer

Keyword(s):

Multiple Sclerosis ◽

Proteolipid Protein ◽

Myelin Proteolipid Protein ◽

Myelin Proteolipid

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Correlation Between Anti-Myelin Proteolipid Protein (PLP) Antibodies and Disease Severity in Multiple Sclerosis Patients With PLP Response-Permissive HLA Types

Frontiers in Immunology ◽

10.3389/fimmu.2020.01891 ◽

2020 ◽

Vol 11 ◽

Author(s):

Judith M. Greer ◽

Elisabeth Trifilieff ◽

Michael P. Pender

Keyword(s):

Multiple Sclerosis ◽

Disease Severity ◽

Proteolipid Protein ◽

Myelin Proteolipid Protein ◽

Multiple Sclerosis Patients ◽

Myelin Proteolipid

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Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls

European Journal of Immunology ◽

10.1002/eji.1830210620 ◽

1991 ◽

Vol 21 (6) ◽

pp. 1461-1468 ◽

Author(s):

Jia-Bin Sun ◽

Tomas Olsson ◽

Wei-Zhi Wang ◽

Bao-Guo Xiao ◽

Vasilios Kostulas ◽

...

Keyword(s):

Multiple Sclerosis ◽

B Cells ◽

Proteolipid Protein ◽

T And B Cells ◽

Myelin Proteolipid Protein ◽

Myelin Proteolipid

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Amino acid variants of myelin proteolipid protein: potential inducers of multiple sclerosis or potential means to a cure?

10.14264/uql.2015.273 ◽

2015 ◽

Author(s):

Nancy Cloake

Keyword(s):

Multiple Sclerosis ◽

Proteolipid Protein ◽

Myelin Proteolipid Protein ◽

Myelin Proteolipid ◽

Amino Acid Variants

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Identification and characterization of a B-cell determinant within the amphipathic domain (residues 178-238) of the myelin proteolipid protein

Journal of Neuroscience Research ◽

10.1002/(sici)1097-4547(19960301)43:5<545::aid-jnr4>3.0.co;2-i ◽

1996 ◽

Vol 43 (5) ◽

pp. 545-553 ◽

Author(s):

T.S. Stephens ◽

M. Pakaski ◽

M.B. Lees ◽

N.T. Potter

Keyword(s):

B Cell ◽

Proteolipid Protein ◽

Myelin Proteolipid Protein ◽

Identification And Characterization ◽

Myelin Proteolipid

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