Unique molecular signatures of antiviral memory CD8+ T cells associated with asymptomatic recurrent ocular herpes

Scientific Reports ◽

10.1038/s41598-020-70673-z ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Swayam Prakash ◽

Soumyabrata Roy ◽

Ruchi Srivastava ◽

Pierre-Gregoire Coulon ◽

Nisha R. Dhanushkodi ◽

...

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Molecular Signatures ◽

Memory Cd8 T Cells ◽

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HLA-A02:01–Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8+T Cells from Seropositive Asymptomatic Individuals and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpes

The Journal of Immunology ◽

10.4049/jimmunol.1402606 ◽

2015 ◽

Vol 194 (5) ◽

pp. 2232-2248 ◽

Author(s):

Ruchi Srivastava ◽

Arif A. Khan ◽

Doran Spencer ◽

Hawa Vahed ◽

Patricia P. Lopes ◽

...

Keyword(s):

T Cells ◽

Herpes Simplex Virus ◽

Herpes Simplex ◽

Cd8 T Cells ◽

Effector Memory ◽

Tegument Protein ◽

Memory Cd8 T Cells ◽

Ocular Herpes ◽

Asymptomatic Individuals ◽

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Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation

Zeitschrift für Gastroenterologie ◽

10.1055/s-0031-1295898 ◽

2012 ◽

Vol 50 (01) ◽

Author(s):

JP Böttcher ◽

D Stabenow ◽

S Debey-Pascher ◽

A Staratschek-Jox ◽

J Grell ◽

...

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Memory Cd8 T Cells ◽

Cross Presentation

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Gene-expression analysis of blood memory CD8+T cells at the single-cell level reveals a specific pattern of clonally expanded cells in multiple sclerosis patients

10.26226/morressier.59a3eda2d462b8028d8949aa ◽

2017 ◽

Author(s):

Emilie Dugast

Keyword(s):

Gene Expression ◽

Multiple Sclerosis ◽

T Cells ◽

Cd8 T Cells ◽

Gene Expression Analysis ◽

Specific Pattern ◽

Single Cell Level ◽

Memory Cd8 T Cells ◽

Multiple Sclerosis Patients

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Faculty Opinions recommendation of Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1006020.74255 ◽

2002 ◽

Author(s):

Hans-Peter Pircher

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Virus Infections ◽

Memory Cd8 T Cells ◽

Persistent Virus

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Faculty Opinions recommendation of IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021799.247714 ◽

2004 ◽

Author(s):

Leo Lefrancois

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Memory Cd8 T Cells ◽

Avidity Maturation

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Faculty Opinions recommendation of Antigen-independent memory CD8 T cells do not develop during chronic viral infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022427.255635 ◽

2004 ◽

Author(s):

Barry Rouse

Keyword(s):

T Cells ◽

Viral Infection ◽

Cd8 T Cells ◽

Chronic Viral Infection ◽

Memory Cd8 T Cells

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Faculty Opinions recommendation of Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025589.301729 ◽

2005 ◽

Author(s):

Ann Hill

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Effector Memory ◽

Memory Cd8 T Cells

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Faculty Opinions recommendation of Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088521.543390 ◽

2007 ◽

Author(s):

Allan Zajac

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Effector Memory ◽

Memory Cd8 T Cells ◽

Memory Phenotype

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Faculty Opinions recommendation of Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115510.571545 ◽

2008 ◽

Author(s):

Eric Denkers

Keyword(s):

T Cells ◽

Chromatin Remodeling ◽

Cd8 T Cells ◽

Molecular Basis ◽

Cutting Edge ◽

Memory Cd8 T Cells

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Faculty Opinions recommendation of Avidity maturation of memory CD8 T cells is limited by self-antigen expression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1117763.573838 ◽

2008 ◽

Author(s):

Ed Palmer

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Antigen Expression ◽

Memory Cd8 T Cells ◽

Self Antigen ◽

Avidity Maturation

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