scholarly journals Ocular manifestations and biomarkers of Gulf War Illness in US veterans

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Brandon S. Baksh ◽  
Kristen L. Zayan ◽  
Raquel Goldhardt ◽  
Elizabeth R. Felix ◽  
Nancy Klimas ◽  
...  
Keyword(s):  
Dry Eye ◽  
Multivariable Analysis ◽  
Disease Diagnosis ◽  
Gulf War ◽  
Gulf War Illness ◽  
Retrospective Case ◽  
Fiber Layer ◽  
Multisystem Disease ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

AbstractGulf War Illness (GWI) is a multisystem disease with variable presentations, making diagnosis difficult. Non-invasive biomarkers would aid in disease diagnosis. We hypothesized that the eye could serve as a biomarker for GWI. We performed a retrospective case–control study using a sample of 1246 patients seen during a 5-month period in an optometry clinic. We identified veterans who were active duty during the Gulf War Era and either had a questionnaire-based diagnosis of GWI (cases) or did not (controls). Medical records were reviewed for eye and medical co-morbidities, medication use, and retinal macular and nerve fiber layer (NFL) thicknesses based on optical coherence tomography (OCT) images. Compared to controls (n = 85), individuals with GWI (n = 60) had a higher frequency of dry eye symptoms (50% vs 32.9%, p = 0.039). Multivariable analysis revealed average retinal NFL thickness (odds ratio; OR = 0.95), cup-to-disc ratio (OR = 0.005), age (OR = 0.82), and PTSD (OR = 20.5) were predictors of a GWI diagnosis. We conclude that GWI is associated with dry eye symptoms and RNFL thinning may serve as a biomarker for disease.

Dry eye symptoms and signs in US veterans with Gulf War Illness

2021 ◽  
Author(s):  
Victor Sanchez ◽  
Brandon S. Baksh ◽  
Kimberly Cabrera ◽  
Anjalee Choudhury ◽  
Katherine Jensen ◽  
...  
Keyword(s):  
Dry Eye ◽  
Gulf War ◽  
Gulf War Illness ◽  
Eye Symptoms ◽  
Us Veterans ◽  
Symptoms And Signs ◽  
Dry Eye Symptoms

scholarly journals The Association between Preoperative Dry Eye Symptoms and Postoperative Discomfort in Patients Underwent Photorefractive Keratectomy

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Gilad Rabina ◽  
Ingibjorg Iris Boguslavsky ◽  
Michael Mimouni ◽  
Igor Kaiserman
Keyword(s):  
Postoperative Pain ◽  
Dry Eye ◽  
Subjective Evaluation ◽  
Case Series ◽  
Photorefractive Keratectomy ◽  
Ocular Surface Disease Index ◽  
Retrospective Case ◽  
Significant Difference ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Purpose. To investigate the association between preoperative dry eye symptoms on postoperative pain and discomfort after photorefractive keratectomy (PRK). Methods. A retrospective case series of 151 consecutive patients, who underwent myopic PRK in both eyes between 5/2016 and 5/2017. Patients with positive dry eye disease (DED) signs on clinical examination or with known DED were excluded. Patients underwent a subjective evaluation for dry eye symptoms using ocular surface disease index (OSDI) and modified standard patient evaluation of eye dryness (SPEED) questionnaires. One day postoperatively, the patients were evaluated again by a questionnaire of pain, discomfort, photophobia, foreign body sensation, satisfaction with vision, and frequency of usage of anesthetic drops. Results. Fifty-two patients had any preoperative dry eye symptoms (OSDI score > 0) compared to 99 nonsymptomatic patients (OSDI score of 0). Postoperatively, the symptomatic dry eye patients suffered significantly more pain than the nondry eye patients (p=0.02). Thirteen patients had a cumulated modified SPEED score >4 (moderate to severe) in comparison to 138 patients with score of 0–4 (non to mild). Patients with moderate to severe preoperative symptoms suffered more pain (p=0.006), photophobia (p=0.005), and epiphora (p=0.03). No statistically significant difference was seen in postoperative subjective visual quality (p=0.82) between the two groups. Conclusion. Preoperative dry eye symptoms may be associated with postoperative pain, epiphora, and photophobia and thus influence negatively on patient satisfaction with this procedure.

Assessment Of Dry Eye Symptoms And Quality Of Sleep In Engineering Students During The Covid-19 Pandemic

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1202-1207
Author(s):  
Pavithra S ◽  
Dheepak Sundar M
Keyword(s):  
Sleep Quality ◽  
Dry Eye ◽  
Screen Time ◽  
Engineering Students ◽  
Statistical Tests ◽  
Quality Of Sleep ◽  
Cross Sectional ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

To assess dry eye symptoms (DES) and quality of sleep in engineering students during the Covid19 pandemic lockdown and also to assess the association between DES and sleep quality. A cross-sectional questionnaire-based study was carried out among 396 engineering students studying in Saveetha engineering college. The study tool used was a semi-structured google form questionnaire designed for assessing digital device usage, symptoms of dry eye disease and sleep pattern. Responses were analyzed using appropriate statistical tests. Overall 64.1% attained a score of more than 10, indicating the presence of DES. 70.2% of the study population used digital screens for more than 13 hours. A statistically significant association was found between increased screen time and presence of DES(p<0.05). 64.9% had a score of >18 indicating reduced sleep quality. About 77.1% of the students with DES had reduced sleep quality, and a significant association (p<0.01) was observed between the two. During the Covid19 pandemic lockdown, there appears to be rising prevalence of DES in student population, one of the reasons being increased screen time. The sleep quality was also found to be reduced, and a significant association was found between DES and sleep quality.

Assessment of dry eye symptoms among university students during the COVID-19 pandemic

2021 ◽  
pp. 1-7
Author(s):  
Diego García-Ayuso ◽  
Johnny Di Pierdomenico ◽  
Esmeralda Moya-Rodríguez ◽  
Francisco J Valiente-Soriano ◽  
Caridad Galindo-Romero ◽  
...  
Keyword(s):  
University Students ◽  
Dry Eye ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Lid Wiper Epitheliopathy and Dry Eye Symptoms

2005 ◽  
Vol 31 (1) ◽  
pp. 2-8 ◽  
Author(s):  
Donald R. Korb ◽  
John P. Herman ◽  
Jack V. Greiner ◽  
Robert C. Scaffidi ◽  
Victor M. Finnemore ◽  
...  
Keyword(s):  
Dry Eye ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

scholarly journals Neuropathic-Like Ocular Pain and Nonocular Comorbidities Correlate With Dry Eye Symptoms

2018 ◽  
Vol 44 ◽  
pp. S307-S313 ◽  
Author(s):  
Victoria S. Chang ◽  
Terri P. Rose ◽  
Carol L. Karp ◽  
Roy C. Levitt ◽  
Constantine Sarantopoulos ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Pain ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

scholarly journals Characteristics of Ocular Pain Complaints in Patients With Idiopathic Dry Eye Symptoms

2017 ◽  
Vol 43 (3) ◽  
pp. 192-198 ◽  
Author(s):  
Jerry P. Kalangara ◽  
Anat Galor ◽  
Roy C. Levitt ◽  
Derek B. Covington ◽  
Katherine T. McManus ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Pain ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Optimum | Tangible Hydra-PEG™ – Gaining Momentum in the Industry

The Eye ◽  
2021 ◽  
Vol 23 (4) ◽  
pp. 31-34
Author(s):  
M. Conway
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Surface Coating ◽  
Clinical Case ◽  
Contact Lenses ◽  
Ocular Surface Disease ◽  
Corneal Ectasia ◽  
Corneal Lens ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

The issue of hydrophilicity of the surface of gas permeable contact lenses remains one of the persistent problems. Tangible Hydra-PEG™ surface coating is applied to gas permeable contact lenses to significantly improve wettability and wearing comfort. Although it is mainly used to alleviate dry eye symptoms in scleral and corneal lens users, particularly for those patients with corneal ectasia and/or Ocular Surface Disease (OSD), it can be used in other modalities. This article describes the development of the product and describes the benefits of its use in a clinical case.

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