Letter: Intravascular injection of local anesthetics

BDJ ◽  
1975 ◽  
Vol 139 (7) ◽  
pp. 263-263
Author(s):  
A K Adatia
BDJ ◽  
1975 ◽  
Vol 139 (5) ◽  
pp. 162-162
Author(s):  
A G Parnell

2020 ◽  
Vol 25 (1) ◽  
Author(s):  
Dmytro Dmytriiev ◽  
Oleksandr Nazarchuk ◽  
Kostiantyn Dmytriiev ◽  
Evgenii Lysak ◽  
Olesya Zaletska

Introduction. The aim of this review was to systematize known facts about the effects of adjuvants to local anesthetics in order to determine adjuvant with the best effect among all others. More precisely the time of action onset, depth of the effect, duration of the block and some additional effects such as “marker of intravascular injection”, safety and toxicity profile, along with the adjuvant, which have all these properties in a sufficient degree. Materials and methods. We searched for information in Medline, PubMed, Scopus, Embase. 105 articles were identified regarding the topic, published since 1989 to 2020. Data from 105 articles about adjuvants to local anesthetics was analyzed and synthesized in this article. Results. Regional methods of analgesia are becoming a crucial part of anesthesiologists’ practice and the knowledge about adjuvants is developing alongside with it, so there are more and more studies devoted to it. All them try to find to find “ideal” adjuvant, that have all needed effects at sufficient degree, but we think that due to the different groups that adjuvants belong to some adjuvants are better than another. Combination of adjuvants is not positive at all times. Conclusion. A variety of adjuvants to local anesthetics are available now, but yet data about most of them remains controversial, so more studies are required to found out best adjuvants and their adverse effects


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Ihab Kamel ◽  
Gaurav Trehan ◽  
Rodger Barnette

Although local anesthetics have an acceptable safety profile, significant morbidity and mortality have been associated with their use. Inadvertent intravascular injection of local anesthetics and/or the use of excessive doses have been the most frequent causes of local anesthetic systemic toxicity (LAST). Furthermore, excessive doses of local anesthetics injected locally into the tissues may lead to inadvertent peripheral nerve infiltration and blockade. Successful treatment of LAST with intralipid has been reported. We describe a case of local anesthetic overdose that resulted in LAST and in unintentional blockade of peripheral nerves of the lower extremity; both effects completely resolved with administration of intralipid.


1992 ◽  
Vol 77 (Supplement) ◽  
pp. A1045
Author(s):  
N. Lingaraju ◽  
P. Colonna-Romano ◽  
D. Seitman

2012 ◽  
Vol 117 (5) ◽  
pp. 1113-1116
Author(s):  
Daniel C. Moore ◽  
Manbir S. Batra

Author(s):  
M.C. Castillo-Jessen ◽  
A. González-Angulo

Information regarding the normal morphology of uterine blood vessels at ultrastructural level in mammals is scarce Electron microscopy studies dealing with endometrial vasculature despite the functional implications due to hormone priming are not available. Light microscopy observations with combined injection of dyes and microradiography along with histochemical studies does not enable us to know the detailed fine structure of the possible various types of blood vessels in this tissue. The present work has been designed to characterize the blood vessels of endometrium of mice as well as the behavior of the endothelium to injection of low molecular weight proteins during the normal estrous cycle in this animal. One hundred and forty female albino mice were sacrificed after intravascular injection of horse radish peroxidase (HRP) at 30 seconds, 5, 15, 30 and 60 minutes.


2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Olufisayo Otusanya

Pulmonary Talcosis is a rare foreign body granulomatous disease that occurs as a result of exposure to talc either by inhalation of talc particles or via intravascular injection of talc containing medications. Pulmonary Talcosis is often misdiagnosed as pulmonary tuberculosis, atypical mycobacterium infection or sarcoidosis as many of their clinical and radiological findings overlap. We report a case of talcosis mimicking mycobacterial disease which was eventually diagnosed via lung biopsy. A detailed history and high index of suspicion is required for timely diagnosis and appropriate management.


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