The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction

Oxygen Species ◽

Caspase Activation ◽

Radical Oxygen Species ◽

Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor β in rat fetal hepatocytes

Hepatology ◽

10.1053/jhep.2001.27447 ◽

2001 ◽

Vol 34 (3) ◽

pp. 548-556 ◽

Cited By ~ 81

Author(s):

B Herrera

Keyword(s):

Growth Factor ◽

Cytochrome C ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Oxygen Species ◽

Radical Oxygen Species ◽

Cytochrome C Release ◽

Down Regulation ◽

Fetal Hepatocytes ◽

Species Production

Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation

The FASEB Journal ◽

10.1096/fasebj.14.7.847 ◽

2000 ◽

Vol 14 (7) ◽

pp. 847-858 ◽

Cited By ~ 147

Author(s):

Carmen García‐Ruiz ◽

Anna Colell ◽

Raquel París ◽

J. C. Fernández‐Checa

Keyword(s):

Reactive Oxygen Species ◽

Cytochrome C ◽

Mitochondrial Permeability Transition ◽

Direct Interaction ◽

Permeability Transition ◽

Oxygen Species ◽

Caspase Activation ◽

Cytochrome C Release ◽

Mitochondrial Permeability ◽

Gd3 Ganglioside

Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis

Cell Death and Differentiation ◽

10.1038/sj.cdd.4400629 ◽

2000 ◽

Vol 7 (2) ◽

pp. 227-233 ◽

Cited By ~ 154

Author(s):

Q Chen ◽

B Gong ◽

A Almasan

Keyword(s):

Cytochrome C ◽

Genotoxic Stress ◽

Caspase Activation ◽

Cytochrome C Release ◽

Amplification Loop ◽

Induced Apoptosis

Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation

Leukemia ◽

10.1038/sj.leu.2402067 ◽

2001 ◽

Vol 15 (4) ◽

pp. 567-574 ◽

Cited By ~ 38

Author(s):

Z Cai ◽

M Lin ◽

C Wuchter ◽

V Ruppert ◽

B Dörken ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Cytochrome C ◽

Reactive Oxygen Species Generation ◽

Reactive Oxygen ◽

Leukemic Cells ◽

Oxygen Species ◽

Mitochondrial Cytochrome ◽

Caspase Activation ◽

Apoptotic Response ◽

Apoptosis is induced by caspase activation and cytochrome c release in photodynamic therapy (PDT) of human hepatoteilular carcinoma cells

Gastroenterology ◽

10.1016/s0016-5085(01)81805-9 ◽

2001 ◽

Vol 120 (5) ◽

pp. A363-A363

Author(s):

A OKUMURA ◽

M HAMBLIN ◽

T HASAN ◽

T ISHIKAWA ◽

S KAKUMU ◽

...

Keyword(s):

Photodynamic Therapy ◽

Cytochrome C ◽

Carcinoma Cells ◽

Caspase Activation ◽

Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction

Cell Death and Differentiation ◽

10.1038/sj.cdd.4400682 ◽

2000 ◽

Vol 7 (6) ◽

pp. 511-520 ◽

Cited By ~ 25

Author(s):

H Ikemoto ◽

E Tani ◽

I Ozaki ◽

H Kitagawa ◽

N Arita

Keyword(s):

Cytochrome C ◽

Cytochrome C Release ◽

Calphostin C

A forskolin derivative, FSK88, induces apoptosis in human gastric cancer BGC823 cells through caspase activation involving regulation of Bcl-2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release

Cell Biology International ◽

10.1016/j.cellbi.2006.06.015 ◽

2006 ◽

Vol 30 (11) ◽

pp. 940-946 ◽

Cited By ~ 6

Author(s):

Z LI ◽

J WANG

Keyword(s):

Gene Expression ◽

Gastric Cancer ◽

Membrane Potential ◽

Cytochrome C ◽

Mitochondrial Membrane Potential ◽

Mitochondrial Membrane ◽

Human Gastric Cancer ◽

Caspase Activation ◽

Cytochrome C Release ◽

Family Gene

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

Cell ◽

10.1016/j.cell.2007.07.012 ◽

2007 ◽

Vol 130 (2) ◽

pp. 385

Author(s):

Anna Colell ◽

Jean-Ehrland Ricci ◽

Stephen Tait ◽

Sandra Milasta ◽

Ulrich Maurer ◽

...

Keyword(s):

Cytochrome C ◽

Caspase Activation ◽

Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.111.180505 ◽

2011 ◽

Vol 339 (2) ◽

pp. 451-463 ◽

Cited By ~ 61

Author(s):

Liu Liu ◽

Chen Chen ◽

Wei Gong ◽

Yuanjing Li ◽

Matthew L. Edin ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Arsenic Trioxide ◽

Reactive Oxygen ◽

Species Level ◽

Carcinoma Cells ◽

Reactive Oxygen Species Level ◽

Epoxyeicosatrienoic Acids ◽

Oxygen Species ◽

Caspase Activation

Extent of Mitochondrial Hexokinase II Dissociation During Ischemia Correlates With Mitochondrial Cytochrome c Release, Reactive Oxygen Species Production, and Infarct Size on Reperfusion

Journal of the American Heart Association ◽

10.1161/jaha.112.005645 ◽

2013 ◽

Vol 2 (1) ◽

Cited By ~ 42

Author(s):

Philippe Pasdois ◽

Joanne Elizabeth Parker ◽

Andrew Philip Halestrap

Keyword(s):

Reactive Oxygen Species ◽

Cytochrome C ◽

Infarct Size ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Oxygen Species ◽

Mitochondrial Cytochrome ◽

Hexokinase Ii ◽

Cytochrome C Release ◽

Species Production