The role of neuregulins in neuroprotection following acute stroke

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S4-S4
Author(s):  
Byron D Ford ◽  
Zhenfeng Xu ◽  
Gregory D Ford ◽  
Alicia Gates ◽  
Ju Jiang
Keyword(s):  
Acute Stroke

The role of nursing in the rehabilitation of acute stroke patients: Toward a unified theoretical perspective

Pflege ◽  
1999 ◽  
Vol 12 (1) ◽  
pp. 21-27
Author(s):  
Marit Kirkevold
Keyword(s):  
Acute Stroke ◽  
Theoretical Perspective ◽  
Stroke Patients ◽  
Role Of Nursing ◽  
Rolle Der Pflegenden

Eine Übersicht der bestehenden Literatur weist auf Unsicherheiten bezüglich der spezifischen Rolle der Pflegenden in der Rehabilitation von Hirnschlagpatientinnen und -patienten hin. Es existieren zwei unterschiedliche Begrifflichkeiten für die Rolle der Pflegenden, keine davon bezieht sich auf spezifische Rehabilitationsziele oder Patientenergebnisse. Ein anfänglicher theoretischer Beitrag der Rolle der Pflege in der Genesung vom Hirnschlag wird als Struktur unterbreitet, um die therapeutischen Aspekte der Pflege im Koordinieren, Erhalten und Üben zu vereinen. Bestehende Literatur untermauert diesen Beitrag. Weitere Forschung ist jedoch notwendig, um den spezifischen Inhalt und Fokus der Pflege in der Genesung bei Hirnschlag zu entwickeln.

Role of acetaminophen in the treatment of acute stroke

2003 ◽  
Vol 3 (2) ◽  
pp. 175-179
Author(s):  
Joshua M Levine ◽  
Scott E Kasner
Keyword(s):  
Acute Stroke

Abstract T MP102: Hotline Use for Recruitment Support in Acute Stroke Trials: Lessons learned To Date in Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-II

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Kathryn A France ◽  
Mushtaq Qureshi ◽  
Jessy Thomas ◽  
Emily Abbott ◽  
Logan Brau ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Lessons Learned ◽  
Local Network ◽  
Drug Management ◽  
Safe Operation ◽  
Team Members ◽  
Clinical Support ◽  
Direct Support ◽  
Protocol Compliance

Background: Use of hotline services for clinical support and safe operation of a research trial is common and important. The value of such services has not been objectively assessed within the context of a large acute stroke clinical trial. Methods: The use of three different hotline services have been tested, and cell and Email- options have also been explored for their advantages. US and Non-US sites are provided access to central hotline services, but for efficiency a local network for managing calls is established in each region. All sites may access both data management and the trial PI via hotline services when needed and this is supported by other technologies in addition. A means for supporting overall trial communications in light of these interactions has been developed and valuable insights are gained. Results: Data gathered from 211 calls logged at the Clinical Coordinating Center through the course of the ATACH-II trial have been summarized: Total Calls Reviewed: 211; Year 2 of trial: 92 calls, Year 3 of trial: 100 calls. Calls received midnight to 8 AM: 19 (9.0%), 8 AM - 5 PM 130 (61.6 %) 5 PM - 12:00 PM 65 (30.8%). Issues Resolved in < 5 min 143/211 (67.8%) Taking > 30 min to resolution 51/211 (24.2%). Purpose of calls: Eligibility 89 (42.2%). protocol compliance including drug management: 77 (36.5%%), randomization/emergency randomization: 16 (7.6%), protocol deviation:13 (6.2%), technological difficulties: 12 (5.7%), AE/SAE: 9 (4.3%), Subject enrollments directly associated with calls: 57 (20.8% of domestic subjects); excluded candidates directly associated with calls: 46 (% not available). Conclusions: In an international trial requiring rapid enrollment of subjects with intracerebral hemorrhage, the role of direct support via a hotline and other immediate communications means has proven to be instrumental in maintaining good protocol compliance and supporting enrollment by site team members .

Role of clinical predictors in determining the need for mechanical ventilation in patients with acute stroke and their outcome- A Prospective observational study

2021 ◽  
Vol 12 (6) ◽  
pp. 16-22
Author(s):  
Maqsood Ahmad Dar ◽  
Eijaz Ahmad Bhat ◽  
Muzzafer M Mir
Keyword(s):  
Mechanical Ventilation ◽  
Mortality Rate ◽  
Acute Stroke ◽  
Developed Countries ◽  
Loss Of Consciousness ◽  
Motor Score ◽  
Clinical Predictors ◽  
Focal Neurological Deficit ◽  
Ventilator Support

Background: Stroke is the third leading cause of death in developed countries and the leading cause of long term disability. As the mortality during initial few days depends upon the compression of vital organs in brain stem due to raised intracranial tension and possible herniation, treatment for impending or early herniation requires intubation and mechanical ventilation and up to 10% of patients with acute stroke need mechanical ventilation due to different reasons. Aims and Objective: The aim of the study was to find the role of clinical predictors in determining the need for mechanical ventilation in patients with acute stroke and their outcome. Materials and Methods: This prospective observational cohort study was conducted from September 2017 to march 2019 of patients with acute stroke admitted either through OPD or Emergency/ Triage of Max super specialty hospital, Saket, New Delhi. Patients with acute Stroke defined as the presence of sudden onset of focal neurological deficit and admitted within 24 h of onset of symptoms with Age ≥18 years were included in the study. Patients already on ventilator support at the time of admission were excluded. Results: A total of 165 patients met the inclusion and exclusion criteria and were enrolled for the study. Out of 165 patients included in the study 43 (26.06 %) were put on the mechanical ventilation due to various reasons. Multivariate analysis of statistically significant and most clinically important variables showed the overall predictor accuracy of requirement of mechanical ventilation of 81.2% if the patients had loss of consciousness at the time of onset ( OR = 0.076) and Glasgow Coma Scale (GCS) motor score of ≤ 5 ( OR= 0.000). About 58.62% (17/29) patients who were put on ventilator support were found to have favorable outcome Modified Rankin Scale (MRS score ≤ 2) at discharge compared to 6.90% (2/29) before ventilation. Conclusion: We concluded that loss of consciousness at onset, GCS motor score ≤ 5 (OR= 0.000) were associated with overall predictor accuracy of 81.2% in determining the need for mechanical ventilation. We found overall in-hospital mortality rate of 9.1% whereas mortality rate in patients on mechanical ventilation was 32.55%.

O-004 Management of acute stroke in elderly patients: examining the role of neurovascular intervention

2011 ◽  
Vol 3 (Suppl_1) ◽  
pp. A2-A2
Author(s):  
J. Maksimovic ◽  
J. Phillips ◽  
K. Fraser ◽  
D. Nair ◽  
D. Wang ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Acute Stroke

scholarly journals Role of Renal Dysfunction as a Prognostic Factor in Acute Stroke Patients at a Tertiary Hospital in Northeastern Nigeria

2021 ◽  
Vol 32 (1) ◽  
pp. 199
Author(s):  
MohammadMaina Sulaiman ◽  
MusaMamman Watila ◽  
Jummai Shettima ◽  
Ibrahim Ummate ◽  
YakubuWilberforce Nyandaiti
Keyword(s):  
Prognostic Factor ◽  
Acute Stroke ◽  
Renal Dysfunction ◽  
Tertiary Hospital ◽  
Stroke Patients

scholarly journals Perfusion magnetic resonance neuroimaging

2019 ◽  
Author(s):  
Adnan Šehić ◽  
Fuad Julardžija ◽  
Merim Jusufbegović ◽  
Deniz Bulja ◽  
Hadžan Konjo ◽  
...  
Keyword(s):  
Blood Flow ◽  
Magnetic Resonance ◽  
Acute Stroke ◽  
Cerebral Perfusion ◽  
Technology Development ◽  
Regional Blood Flow ◽  
Mr Perfusion ◽  
Endovascular Recanalization

The clinical appliance of perfusion is being continuously developed and it is closely related to technology development. The role of perfusion neuroimaging in the management of acute stroke has been to prove reduced regional blood flow and to give the contribution in the identification of ischemic areas, respectively the regions of hypoperfusion that can be treated by thrombolytic and/or endovascular recanalization therapy. There are two main approaches to the measurement of cerebral perfusion by magnetic resonance. The aim of this article is to compare different measuring approaches of MR perfusion neuroimaging.

The role of neuroimaging in selecting treatments for patients with acute stroke

2001 ◽  
Vol 1 (1) ◽  
pp. 26-32
Author(s):  
David Greer ◽  
Jamary Oliveira-Filho ◽  
Walter J. Koroshetz
Keyword(s):  
Acute Stroke
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