scholarly journals Post traumatic distress symptoms following spinal cord injury: a comparative review of European Samples

Spinal Cord ◽  
2004 ◽  
Vol 43 (2) ◽  
pp. 102-108 ◽  
Author(s):  
P Lude ◽  
P Kennedy ◽  
M Evans ◽  
Y Lude ◽  
A Beedie
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Distress Symptoms ◽  
Comparative Review ◽  
Cord Injury ◽  
Post Traumatic ◽  
Traumatic Distress

Numerical Investigation of Spinal Cord Injury After Flexion-Distraction Injuries At the Cervical Spine

2021 ◽  
Author(s):  
Marie-Helene Beausejour ◽  
Eric Wagnac ◽  
Pierre-Jean Arnoux ◽  
Jean-Marc Mac-Thiong ◽  
Yvan Petit
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cervical Spine ◽  
White Matter ◽  
Cervical Spinal Cord ◽  
Element Model ◽  
Von Mises Stress ◽  
Study Objective ◽  
Cord Injury ◽  
Post Traumatic

Abstract Flexion-distraction injuries frequently cause traumatic cervical spinal cord injury (SCI). Post-traumatic instability can cause aggravation of the secondary SCI during patient's care. However, there is little information on how the pattern of disco-ligamentous injury affects the SCI severity and mechanism. This study objective was to analyze how different flexion-distraction disco-ligamentous injuries affect the SCI mechanisms during post-traumatic flexion and extension. A cervical spine finite element model including the spinal cord was used and different combinations of partial or complete intervertebral disc (IVD) rupture and disruption of various posterior ligaments were modeled at C4-C5, C5-C6 or C6-C7. In flexion, complete IVD rupture combined with posterior ligamentous complex rupture was the most severe injury leading to the most extreme von Mises stress (47 to 66 kPa), principal strains p1 (0.32 to 0.41 in white matter) and p3 (-0.78 to -0.96 in white matter) in the spinal cord and to the most important spinal cord compression (35 to 48 %). The main post-trauma SCI mechanism was identified as compression of the anterior white matter at the injured level combined with distraction of the posterior spinal cord during flexion. There was also a concentration of the maximum stresses in the gray matter after injury. Finally, in extension, the injuries tested had little impact on the spinal cord. The capsular ligament was the most important structure in protecting the spinal cord. Its status should be carefully examined during patient's management.

scholarly journals Nanoparticles guided precise transplantation of varying numbers of mesenchymal stem cells into post–traumatic syrinx in spinal cord injury rat

2018 ◽  
pp. 49-56
Author(s):  
Chao Zhang ◽  
A.Y. Morozova ◽  
V.P. Baklaushev ◽  
I.L. Gubsky ◽  
P.A. Melnikov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Mesenchymal Stem Cells ◽  
Magnetic Nanoparticles ◽  
Diffusion Tensor ◽  
Cell Number ◽  
Functional Improvement ◽  
Cord Injury ◽  
Post Traumatic

Spinal cord injury (SCI) is a traumatic injury to the spinal cord which is not a consequence of the disease. Mesenchymal stem cells (MSCs) have gradually become one of the most used stem cells in research and clinic trial. Based on the previous reports employed the cells ranged from 4 • 105 to 1 • 106, the present study was performed to figure out the best number of MSCs for transplantation of the chronic SCI. Magnetic nanoparticles were used for proving the precise transplantation strategy. Using magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), diffusion tensor tractography (DTT), and behavior testing evaluations, we focused the effect of varying numbers of MSCs on reducing lesion cavity and post–traumatic syrinx formation, suppressing glial scar formation, enhancing neuronal fibers remodeling, promoting axonal regeneration and sprouting, improving vascularization, ameliorating the neuronal factors expressional level, and function improvement. Magnetic nanoparticles were precisely transplanted into the post–traumatic syrinx (PTS). MSCs can restore function after chronic SCI through stimulating the regeneration and sprouting of the axons, reducing the formation of PTS. The effect of MSCs on PTS management and functional improvement post chronic SCI was cell number–dependent, and within the range of 4 • 105 to 1 • 106, 1 • 106 cells were proved to be the best dose.

The moderation of resilience on the negative effect of pain on depression and post-traumatic growth in individuals with spinal cord injury

2013 ◽  
Vol 36 (14) ◽  
pp. 1196-1202 ◽  
Author(s):  
Jung-Ah Min ◽  
Chang-Uk Lee ◽  
Sung-Il Hwang ◽  
Jung-In Shin ◽  
Bum-Suk Lee ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Post Traumatic Growth ◽  
Cord Injury ◽  
Negative Effect ◽  
Post Traumatic

scholarly journals Diffusion Tensor Imaging in Diagnosis of Post-Traumatic Syringomyelia in Spinal Cord Injury in Rats

2018 ◽  
Vol 24 ◽  
pp. 177-182 ◽  
Author(s):  
Chao Zhang ◽  
Kai Chen ◽  
Xiuxin Han ◽  
Jiayuanyuan Fu ◽  
Patricia Douglas ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Cord Injury ◽  
Post Traumatic

Intrathecal phenol and glycerin in metrizamide for treatment of intractable spasms in paraplegia

1985 ◽  
Vol 63 (1) ◽  
pp. 125-127 ◽  
Author(s):  
Brett A. Scott ◽  
Zelig Weinstein ◽  
Robert Chiteman ◽  
Morris W. Pulliam
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cerebrospinal Fluid ◽  
Intrathecal Injection ◽  
Fluoroscopic Guidance ◽  
Content Type ◽  
Therapeutic Modalities ◽  
Comparative Review ◽  
Cord Injury ◽  
Fine Print

✓ Intractable lower extremity spasms after spinal cord injury is a significant source of morbidity. A case of refractory spasticity in paraplegia was successfully converted to flaccid paraplegia by intrathecal injection of phenol and glycerin in metrizamide. This chemical rhizolysis is simple and effective, and the presence of metrizamide allows both fluoroscopic guidance for accurate intrathecal phenol placement and good miscibility with cerebrospinal fluid. A brief comparative review of alternative therapeutic modalities is presented.

Progressive post-traumatic syringomyelia: a clinical case

2019 ◽  
Vol 21 (4) ◽  
pp. 81-88
Author(s):  
F. A. Bushkov ◽  
M. A. Bzhylyanskiy ◽  
A. Yu. Kordonskiy
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Informed Consent ◽  
Conflict Of Interest ◽  
Clinical Case ◽  
Spinal Injury ◽  
Spinal Column ◽  
Cord Injury ◽  
Post Traumatic ◽  
The Right

The objective of the present article is to describe a rare clinical case of progressive post-traumatic cervical syringomyelia after spinal cord injury with fracture of proximal metaepiphysis of the right humerus. The patient had a progressive neurological loss after spinal cord injury.Materials and methods. The patient underwent surgical treatment: decompression and stabilization of spinal column, surgical technique of spinal cord detethering, cyst shunting.Results. In the postoperative period the patient had increased spasticity in the lower extremities, increased weakness in the muscles of the upper extremities, aggravation of orthostatic hypotension, and inability to flex the first and the fifth fingers of the right hand. Magnetic resonance imaging of the cervical spine revealed progression of syringomyelia.Conclusion. This case demonstrates differentiation between cervical myelopathy and plexus paresis in a patient with combination spinal injury and reveals the mechanisms underlying late progression of neurological deficit.Conflict of interest. The authors declare no conflict of interest.Informed consent. The patient gave written informed consent to the publication of his data.

Long-term outcome of paediatric spinal cord injury

Trauma ◽  
2017 ◽  
Vol 19 (1_suppl) ◽  
pp. 75-82 ◽  
Author(s):  
Richa Kulshrestha ◽  
Naveen Kumar ◽  
J Roy Chowdhury ◽  
Aheed Osman ◽  
W El Masri
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Spinal Cord Injuries ◽  
Spinal Injury ◽  
Social Outcomes ◽  
Long Term Outcomes ◽  
Cord Injury ◽  
Post Traumatic ◽  
Clinical Records

Background Spinal cord injuries are relatively uncommon in children and evidence about long-term outcomes is limited. This study was performed to determine the frequency of common long-term complications in patients sustaining spinal injury in childhood (0–18 years) and who were followed up at a single dedicated spinal injuries centre in the UK. Method A retrospective review of clinical records of all patients injured at or less than 18 years of age between 1971 and 1999. Complications studied were renal, bowel, musculoskeletal, pressure ulcers and post-traumatic syringomyelia. Long-term social outcomes of independence, employment and driving were also assessed. Results Of 69 individuals (47 males, 22 females) the median age at injury was 17 years (range 0–18 y); 68% were older than 13 years at injury and 74% had traumatic injuries. Patients had an average duration of 27 years (12–43 years) of spinal injury – half had a neurological level of T6 and above, 80% had paraplegia and 20% had quadriplegia. Discussion Patients with both complete and incomplete spinal cord injury have minimal neurological recovery. Managing medical complications is vital as only 11.5% had normal voiding and 10.6% had normal bowel function. The incidence of skin ulcers increases with duration of spinal cord injury and scoliosis is higher in the non-traumatic injury group. Spasticity is observed in 66.6% and post-traumatic syringomyelia in 11.7%. Long-term social outcomes are good with 75% patients able to do independent care, 46% could drive and 39% managed employment or higher education. Conclusions This study documents the long-term outcomes and complications of spinal cord injuries sustained in childhood. With initial active physiological conservative management of the majority of patients, patient education and ongoing support the majority of patients achieved long-term survival and led independent and productive lives.

Sign in / Sign up

Export Citation Format

Share Document