How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase

The Analyst ◽  
2011 ◽  
Vol 136 (1) ◽  
pp. 20-28 ◽  
Author(s):  
Ewa Jurneczko ◽  
Perdita E. Barran
Keyword(s):  
Mass Spectrometry ◽  
Crystal Structures ◽  
Gas Phase ◽  
Structural Biology ◽  
Cross Sections ◽  
Ion Mobility ◽  
Protein Crystal ◽  
Ion Mobility Mass Spectrometry ◽  
Collision Cross Sections ◽  
The Relationship

scholarly journals Collision cross sections of high-mannose N-glycans in commonly observed adduct states – identification of gas-phase conformers unique to [M − H]− ions

The Analyst ◽  
2015 ◽  
Vol 140 (20) ◽  
pp. 6799-6803 ◽  
Author(s):  
W. B. Struwe ◽  
J. L. Benesch ◽  
D. J. Harvey ◽  
K. Pagel
Keyword(s):  
Mass Spectrometry ◽  
Gas Phase ◽  
Cross Sections ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry ◽  
Collision Cross Sections ◽  
High Mannose

We report collision cross sections (CCS) of high-mannose N-glycans as [M + Na]+, [M + K]+, [M + H]+, [M + Cl]−, [M + H2PO4]− and [M − H]− ions, measured by drift tube (DT) ion mobility-mass spectrometry (IM-MS) in helium and nitrogen gases.

scholarly journals EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data

The Analyst ◽  
2016 ◽  
Vol 141 (1) ◽  
pp. 70-75 ◽  
Author(s):  
Matteo T. Degiacomi ◽  
Justin L. P. Benesch
Keyword(s):  
Electron Microscopy ◽  
Mass Spectrometry ◽  
Structural Biology ◽  
Cross Sections ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Density Maps ◽  
Transmission Electron ◽  
Microscopy Data ◽  
Means Of Transmission

EM∩IM enables the calculation of collision cross-sections from electron density maps obtained, for example, by means of transmission electron microscopy. This capability will further aid the integration of ion mobility mass spectrometry with modern structural biology.

Estimating Collision Cross Sections of Negatively Charged N-Glycans using Traveling Wave Ion Mobility-Mass Spectrometry

2014 ◽  
Vol 86 (21) ◽  
pp. 10789-10795 ◽  
Author(s):  
Johanna Hofmann ◽  
Weston B. Struwe ◽  
Charlotte A. Scarff ◽  
James H. Scrivens ◽  
David J. Harvey ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cross Sections ◽  
Ion Mobility ◽  
Traveling Wave ◽  
Ion Mobility Mass Spectrometry ◽  
Collision Cross Sections ◽  
Traveling Wave Ion Mobility
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