Ruthenium complexes containing 2,6-bis(benzimidazolyl)pyridine derivatives induce cancer cell apoptosis by triggering DNA damage-mediated p53 phosphorylation

2012 ◽  
Vol 41 (41) ◽  
pp. 12766 ◽  
Author(s):  
Linlin Li ◽  
Wenqiang Cao ◽  
Wenjie Zheng ◽  
Cundong Fan ◽  
Tianfeng Chen
Keyword(s):  
Dna Damage ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Ruthenium Complexes ◽  
Pyridine Derivatives ◽  
Cancer Cell Apoptosis ◽  
Induce Cancer Cell Apoptosis

Cancer-associated fibroblasts induce cancer cell apoptosis that regulates invasion mode of tumours

Oncogene ◽  
2017 ◽  
Vol 36 (31) ◽  
pp. 4434-4444 ◽  
Author(s):  
G Itoh ◽  
S Chida ◽  
K Yanagihara ◽  
M Yashiro ◽  
N Aiba ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Cell Apoptosis ◽  
Cancer Associated Fibroblasts ◽  
Cancer Cell Apoptosis ◽  
Induce Cancer Cell Apoptosis

scholarly journals Counterion coupled (COCO) gemini surfactant capped Ag/Au alloy and core–shell nanoparticles for cancer therapy

RSC Advances ◽  
2019 ◽  
Vol 9 (65) ◽  
pp. 37830-37845 ◽  
Author(s):  
A. Mohammed Siddiq ◽  
Ramar Thangam ◽  
Balaraman Madhan ◽  
Md. Sayem Alam
Keyword(s):  
Dna Damage ◽  
Cancer Therapy ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Gemini Surfactant ◽  
Au Nanoparticles ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Cancer Cell Apoptosis ◽  
Core Shell Nanoparticles

In this work hybrid silver (Ag)–gold (Au) nanoparticles (NPs) with different sizes and compositions were synthesized and applied for anticancer evaluations and which is effectively involved in cancer cell apoptosis through DNA damage.

Facile synthesis of highly uniform selenium nanoparticles using glucose as the reductant and surface decorator to induce cancer cell apoptosis

2016 ◽  
Vol 4 (13) ◽  
pp. 2351-2358 ◽  
Author(s):  
Tianqi Nie ◽  
Hualian Wu ◽  
Ka-Hing Wong ◽  
Tianfeng Chen
Keyword(s):  
Mitochondrial Dysfunction ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Selenium Nanoparticles ◽  
Facile Synthesis ◽  
Cancer Cell Apoptosis ◽  
Intracellular Ros ◽  
Induction Of Apoptosis ◽  
Highly Uniform ◽  
Induce Cancer Cell Apoptosis

Herein, we demonstrated a new and facial synthesis of highly uniformed SeNPs using glucose as the reductant and surface decorator. Glu–SeNPs induced cancer cell apoptosisviainduction of apoptosis by triggering intracellular ROS overproduction and mitochondrial dysfunction.

Photothermal and photodynamic therapy reagents based on rGO–C6H4–COOH

RSC Advances ◽  
2016 ◽  
Vol 6 (5) ◽  
pp. 3748-3755 ◽  
Author(s):  
Guangcheng Wei ◽  
Miaomiao Yan ◽  
Liying Ma ◽  
Chunhua Wang
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Cancer Cell Apoptosis ◽  
Induce Cancer Cell Apoptosis

A photothermal and photodynamic therapy reagent based on rGO–C6H4–COOH was developed, which could effectively induce cancer cell apoptosis.

scholarly journals Ku70 inhibits gemcitabine-induced DNA damage and pancreatic cancer cell apoptosis

2017 ◽  
Vol 484 (4) ◽  
pp. 746-752 ◽  
Author(s):  
Jiali Ma ◽  
Pingping Hui ◽  
Wenying Meng ◽  
Na Wang ◽  
Shihao Xiang
Keyword(s):  
Pancreatic Cancer ◽  
Dna Damage ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Pancreatic Cancer Cell ◽  
Cancer Cell Apoptosis

scholarly journals p53/microRNA-374b/AKT1 regulates colorectal cancer cell apoptosis in response to DNA damage

2017 ◽  
Vol 50 (5) ◽  
pp. 1785-1791 ◽  
Author(s):  
Hangjun Gong ◽  
Yu Cao ◽  
Gang Han ◽  
Yun Zhang ◽  
Qing You ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dna Damage ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Apoptosis

Anti-hepatoma activity of the stiff branched β-d-glucan and effects of molecular weight

2016 ◽  
Vol 4 (26) ◽  
pp. 4565-4573 ◽  
Author(s):  
Zhaohua Ping ◽  
Hui Xu ◽  
Ting Liu ◽  
Junchao Huang ◽  
Yan Meng ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Immune Responses ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Water Soluble ◽  
Auricularia Auricula ◽  
Cancer Cell Apoptosis ◽  
Induce Cancer Cell Apoptosis

The water soluble β-d-glucan AF1 with short branches isolated from Auricularia auricula-judae exhibited significant anti-hepatoma activities, and it was confirmed that AF1 had stiff chains and could induce cancer cell apoptosis and anti-angiogenesis through activating immune responses.

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