A novel electrochemical aptasensor for thrombin detection based on the hybridization chain reaction with hemin/G-quadruplex DNAzyme-signal amplification

The Analyst ◽  
2013 ◽  
Vol 138 (16) ◽  
pp. 4558 ◽  
Author(s):  
Juan Zhang ◽  
Yaqin Chai ◽  
Ruo Yuan ◽  
Yali Yuan ◽  
Lijuan Bai ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Hybridization Chain Reaction ◽  
Electrochemical Aptasensor ◽  
Chain Reaction ◽  
G Quadruplex

MoS2-loaded G-quadruplex molecular beacon probes for versatile detection of MicroRNA through hybridization chain reaction signal amplification

Talanta ◽  
2019 ◽  
Vol 202 ◽  
pp. 342-348 ◽  
Author(s):  
Feng Zhang ◽  
Shuang Wang ◽  
Jian feng ◽  
Rong Zou ◽  
Ling Xiang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Molecular Beacon ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
G Quadruplex

Lab in a tube: a fast-assembled colorimetric sensor for highly sensitive detection of oligonucleotides based on a hybridization chain reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44714-44721 ◽  
Author(s):  
Siqi Zhang ◽  
Kun Wang ◽  
Zhenyu Li ◽  
Zhongmin Feng ◽  
Ting Sun
Keyword(s):  
Complex Formation ◽  
Dna Sequence ◽  
Self Assembly ◽  
The Self ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
G Quadruplex ◽  
Colored Product ◽  
Highly Sensitive Detection

Upon adding THBV, the self-assembly of THBV with H1 allows the rest of the DNA sequence of H1 to accelerate H1–H2 complex formation. The G-quadruplex at the end of the H1–H2 complex could catalyze TMB into a colored product.

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