Lab in a tube: a fast-assembled colorimetric sensor for highly sensitive detection of oligonucleotides based on a hybridization chain reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44714-44721 ◽  
Author(s):  
Siqi Zhang ◽  
Kun Wang ◽  
Zhenyu Li ◽  
Zhongmin Feng ◽  
Ting Sun
Keyword(s):  
Complex Formation ◽  
Dna Sequence ◽  
Self Assembly ◽  
The Self ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
G Quadruplex ◽  
Colored Product ◽  
Highly Sensitive Detection

Upon adding THBV, the self-assembly of THBV with H1 allows the rest of the DNA sequence of H1 to accelerate H1–H2 complex formation. The G-quadruplex at the end of the H1–H2 complex could catalyze TMB into a colored product.

scholarly journals Highly sensitive detection of lipopolysaccharides using an aptasensor based on hybridization chain reaction

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Peiyan Xie ◽  
Longjiao Zhu ◽  
Xiangli Shao ◽  
Kunlun Huang ◽  
Jingjing Tian ◽  
...  
Keyword(s):  
Sensitive Detection ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Dual signal-amplification electrochemical detection of DNA sequence based on molybdenum selenide nanorod and hybridization chain reaction

2016 ◽  
Vol 8 (26) ◽  
pp. 5234-5241 ◽  
Author(s):  
Liu Yang ◽  
Yanfu Li
Keyword(s):  
Dna Sequences ◽  
Signal Amplification ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Molybdenum Selenide ◽  
Highly Sensitive ◽  
Immunodeficiency Virus ◽  
Highly Sensitive Detection ◽  
Dual Signal Amplification

A new electrochemical biosensor based on the hybridization chain reaction and layered molybdenum selenide (MoSe2) stacked nanorod for dual-signal amplification is developed for the highly sensitive detection of the DNA sequences of Human Immunodeficiency Virus type 1 (HIV-1).

A triple-amplification strategy based on the formation of peroxidase-like two-dimensional DNA/Fe3O4 networks initiated by the hybridization chain reaction for highly sensitive detection of microRNA

2019 ◽  
Vol 55 (58) ◽  
pp. 8386-8389 ◽  
Author(s):  
Sheng Tang ◽  
Yana Li ◽  
Anni Zhu ◽  
Yao Yao ◽  
Jun Sun ◽  
...  
Keyword(s):  
Sensitive Detection ◽  
Hybridization Chain Reaction ◽  
Two Dimensional ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Amplification Strategy

Peroxidase-like two-dimensional DNA/Fe3O4 networks were constructed by the hybridization chain reaction and applied to detect microRNA down to the aM level.

DNA logic assembly powered by a triplex-helix molecular switch for extracellular pH imaging

2018 ◽  
Vol 54 (61) ◽  
pp. 8498-8501 ◽  
Author(s):  
Hongjie Qi ◽  
Shuzhen Yue ◽  
Sai Bi ◽  
Caifeng Ding ◽  
Weiling Song
Keyword(s):  
Self Assembly ◽  
Molecular Switch ◽  
Extracellular Ph ◽  
The Self ◽  
Hybridization Chain Reaction ◽  
Dna Nanostructures ◽  
Chain Reaction ◽  
Molecular Logic ◽  
Ph Imaging ◽  
Logic Operations

A strategy is rationally designed to finely control the hybridization chain reaction (HCR) for the self-assembly of DNA nanostructures by simply changing the pH, which is successfully applied to molecular logic operations and extracellular pH imaging.

Highly sensitive detection of cancer cells via split aptamer mediated proximity-induced hybridization chain reaction

Talanta ◽  
2021 ◽  
Vol 223 ◽  
pp. 121724
Author(s):  
Lie Li ◽  
Huishan Jiang ◽  
Xiangxian Meng ◽  
Xiaohong Wen ◽  
Qiuping Guo ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Sensitive Detection ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Antibody-powered DNA switches to initiate hybridization chain reaction for amplified fluorescence immunoassay

The Analyst ◽  
2021 ◽  
Author(s):  
Jiayang He ◽  
Zehui Chen ◽  
Huilin Deng ◽  
Ruo Yuan ◽  
Wenju Xu
Keyword(s):  
Sensitive Detection ◽  
Hybridization Chain Reaction ◽  
Fluorescence Immunoassay ◽  
Chain Reaction ◽  
Specific Antibodies ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Dna Switches

Designing antibody-powered DNA nanodevice switches is crucial and fascinating to perform a variety of functions in response to specific antibodies as regulatory inputs, achieving the highly sensitive detection by integrating...

Netlike hybridization chain reaction assembly of DNA nanostructures enables exceptional signal amplification for sensing trace cytokines

Nanoscale ◽  
2019 ◽  
Vol 11 (35) ◽  
pp. 16362-16367 ◽  
Author(s):  
Yao Qin ◽  
Daxiu Li ◽  
Ruo Yuan ◽  
Yun Xiang
Keyword(s):  
Signal Amplification ◽  
Sensitive Detection ◽  
Hybridization Chain Reaction ◽  
Dna Nanostructures ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Target-induced assembly formation of netlike DNA nanostructures leads to highly sensitive detection of cytokines.

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