Imaging of Cancer Cells and Dictated Cytotoxicity Using Aptamer‐Guided Hybridization Chain Reaction (HCR)‐Generated G‐Quadruplex Chains

2021 ◽  
Author(s):  
Amily Fang-Ju Jou ◽  
Yi-Te Chou ◽  
Itamar Willner ◽  
Ja-an Annie Ho
Keyword(s):  
Cancer Cells ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
G Quadruplex

An electrochemiluminescence assay for sensitive detection of methyltransferase activity in different cancer cells by hybridization chain reaction coupled with a G-quadruplex/hemin DNAzyme biosensing strategy

The Analyst ◽  
2017 ◽  
Vol 142 (11) ◽  
pp. 2013-2019 ◽  
Author(s):  
Hui Zhang ◽  
Zhihui Guo ◽  
Huilei Dong ◽  
Hongfei Chen ◽  
Chenxin Cai
Keyword(s):  
Cancer Cells ◽  
Sensitive Detection ◽  
Hybridization Chain Reaction ◽  
Methyltransferase Activity ◽  
Chain Reaction ◽  
G Quadruplex

A sensitive electrochemiluminescence assay coupled HCR with a G-quadruplex/hemin DNAzyme was fabricated for the detection of DNMT1 activity in cancer cells.

Lab in a tube: a fast-assembled colorimetric sensor for highly sensitive detection of oligonucleotides based on a hybridization chain reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44714-44721 ◽  
Author(s):  
Siqi Zhang ◽  
Kun Wang ◽  
Zhenyu Li ◽  
Zhongmin Feng ◽  
Ting Sun
Keyword(s):  
Complex Formation ◽  
Dna Sequence ◽  
Self Assembly ◽  
The Self ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
G Quadruplex ◽  
Colored Product ◽  
Highly Sensitive Detection

Upon adding THBV, the self-assembly of THBV with H1 allows the rest of the DNA sequence of H1 to accelerate H1–H2 complex formation. The G-quadruplex at the end of the H1–H2 complex could catalyze TMB into a colored product.

An enzyme-free and label-free fluorescent biosensor for small molecules by G-quadruplex based hybridization chain reaction

Talanta ◽  
2015 ◽  
Vol 138 ◽  
pp. 15-19 ◽  
Author(s):  
Qingai Chen ◽  
Qingquan Guo ◽  
Ying Chen ◽  
Jie Pang ◽  
Fengfu Fu ◽  
...  
Keyword(s):  
Small Molecules ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Fluorescent Biosensor ◽  
G Quadruplex

Multivalent Capture and Detection of Cancer Cells with DNA Nanostructured Biosensors and Multibranched Hybridization Chain Reaction Amplification

2014 ◽  
Vol 86 (15) ◽  
pp. 7843-7848 ◽  
Author(s):  
Guobao Zhou ◽  
Meihua Lin ◽  
Ping Song ◽  
Xiaoqing Chen ◽  
Jie Chao ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Reaction Amplification

Electrochemical detection of sequence-specific DNA based on formation of G-quadruplex-hemin through continuous hybridization chain reaction

2018 ◽  
Vol 1021 ◽  
pp. 121-128 ◽  
Author(s):  
Xiaofan Sun ◽  
Haohan Chen ◽  
Shuling Wang ◽  
Yiping Zhang ◽  
Yaping Tian ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
G Quadruplex
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