A lab-in-a-droplet bioassay strategy for centrifugal microfluidics with density difference pumping, power to disc and bidirectional flow control

Lab on a Chip ◽  
2013 ◽  
Vol 13 (18) ◽  
pp. 3698 ◽  
Author(s):  
Guanghui Wang ◽  
Ho-Pui Ho ◽  
Qiulan Chen ◽  
Alice Kar-Lai Yang ◽  
Ho-Chin Kwok ◽  
...  



2012 ◽  
Vol 700 ◽  
pp. 406-418 ◽  
Author(s):  
Bettina Frohnapfel ◽  
Yosuke Hasegawa ◽  
Maurizio Quadrio

AbstractFlow control with the goal of reducing the skin-friction drag on the fluid–solid interface is an active fundamental research area, motivated by its potential for significant energy savings and reduced emissions in the transport sector. Customarily, the performance of drag reduction techniques in internal flows is evaluated under two alternative flow conditions, i.e. at constant mass flow rate or constant pressure gradient. Successful control leads to reduction of drag and pumping power within the former approach, whereas the latter leads to an increase of the mass flow rate and pumping power. In practical applications, however, money and time define the flow control challenge: a compromise between the energy expenditure (money) and the corresponding convenience (flow rate) achieved with that amount of energy has to be reached so as to accomplish a goal which in general depends on the specific application. Based on this idea, we derive two dimensionless parameters which quantify the total energy consumption and the required time (convenience) for transporting a given volume of fluid through a given duct. Performances of existing drag-reduction strategies as well as the influence of wall roughness are re-evaluated within the present framework; how to achieve the (application-dependent) optimum balance between energy consumption and convenience is addressed. It is also shown that these considerations can be extended to external flows.



Lab on a Chip ◽  
2019 ◽  
Vol 19 (16) ◽  
pp. 2718-2727 ◽  
Author(s):  
Daniel M. Kainz ◽  
Susanna M. Früh ◽  
Tobias Hutzenlaub ◽  
Roland Zengerle ◽  
Nils Paust

Lateral flow strips (LFSs) are widely used for clinical diagnostics. The restricted flow control is one challenge to the development of quantitative and highly sensitive LFSs. Here, we present a flow control for LFSs using centrifugal microfluidics.





Lab on a Chip ◽  
2005 ◽  
Vol 5 (2) ◽  
pp. 146-150 ◽  
Author(s):  
Thilo Brenner ◽  
Thomas Glatzel ◽  
Roland Zengerle ◽  
Jens Ducrée




2020 ◽  
Vol 25 (4) ◽  
pp. 28-36
Author(s):  
S. Matthew Gibson ◽  
Jonathan Primeaux

Highlights NC labeling does not appear to correspond with manufacturer claims. Two of 13 NCs passed the test for bidirectional flow control. All NCs reflux either on connection or disconnection. Neutral displacement does not appear to be present in the NCs tested in this observational study. Accurate bidirectional flow control, reflux cycle, and volume of reflux beyond the manufacturer’s performance claims will assist in the proper use of NCs.





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