In situ electrochemical synthesis of Ni-capped electrochemiluminescence nanoprobe for ultrasensitive detection of cancer cells

2015 ◽  
Vol 7 (4) ◽  
pp. 1438-1445 ◽  
Author(s):  
Qingqing Wen ◽  
Pei-Hui Yang

A facile, novel and in situ electrochemical synthesis of a Ni-capped (NiS@CdS/PANINF) composite electrochemiluminescence (ECL) nanoprobe was developed to fabricate an ECL cytosensor for the ultrasensitive detection of cancer cells.

2021 ◽  
Vol 714 (3) ◽  
pp. 032008
Author(s):  
Hongmei Li ◽  
Zhisheng Nong ◽  
Qian Xu ◽  
Qiushi Song ◽  
Ying Chen ◽  
...  

Author(s):  
Ze-Kun Wang ◽  
Jia-Le Lin ◽  
Yun-Chang Zhang ◽  
Chen-Wu Yang ◽  
Ya-Kun Zhao ◽  
...  
Keyword(s):  

Water-soluble hydrazone-connected 3D flexible organic frameworks have been revealed to in situ load and deliver short DNA into normal and cancer cells.


2017 ◽  
Vol 19 (44) ◽  
pp. 29880-29885 ◽  
Author(s):  
Eva-Maria Steyskal ◽  
Michael Seidl ◽  
Matthias Graf ◽  
Roland Würschum

The progress of dealloying, an electrochemical synthesis method capable of producing nanoporous structures with bulk outer dimensions, is studied by in situ resistometry.


2013 ◽  
Vol 289 (3) ◽  
pp. 1303-1312 ◽  
Author(s):  
Qinglin Li ◽  
Gabriel Eades ◽  
Yuan Yao ◽  
Yongshu Zhang ◽  
Qun Zhou

Previously, we found that basal-like ductal carcinoma in situ (DCIS) contains cancer stem-like cells. Here, we characterize stem-like subpopulations in a model of basal-like DCIS and identify subpopulations of CD49f+/CD24− stem-like cells that possess aldehyde dehydrogenase 1 activity. We found that these cells show enhanced migration potential compared with non-stem DCIS cells. We also found that the chemopreventive agent sulforaphane can target these DCIS stem-like cells, reduce aldehyde dehydrogenase 1 (ALDH1) expression, and decrease mammosphere and progenitor colony formation. Furthermore, we characterized exosomal trafficking of microRNAs in DCIS and found that several microRNAs (miRs) including miR-140, miR-29a, and miR-21 are differentially expressed in exosomes from DCIS stem-like cells. We found that SFN treatment could reprogram DCIS stem-like cells as evidenced by significant changes in exosomal secretion more closely resembling that of non-stem cancer cells. Finally, we demonstrated that exosomal secretion of miR-140 might impact signaling in nearby breast cancer cells.


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