A size amplified immune magnetic microbeads strategy in the rapid detection of circulating tumor cells

2014 ◽  
Vol 50 (53) ◽  
pp. 7024-7027 ◽  
Author(s):  
Hongyan Zhang ◽  
Yanhong Wang ◽  
Qingling Li ◽  
Fumiao Zhang ◽  
Bo Tang

A size amplified immune magnetic microbeads strategy for the combined use of membrane filtration and immune-magnetic separation in CTC detection.

Nano Research ◽  
2014 ◽  
Vol 7 (9) ◽  
pp. 1327-1336 ◽  
Author(s):  
Shuai Fang ◽  
Chao Wang ◽  
Jian Xiang ◽  
Liang Cheng ◽  
Xuejiao Song ◽  
...  

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Chang Eun Yoo ◽  
Jong-Myeon Park ◽  
Hui-Sung Moon ◽  
Je-Gun Joung ◽  
Dae-Soon Son ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3525
Author(s):  
Peng Liu ◽  
Pascal Jonkheijm ◽  
Leon W. M. M. Terstappen ◽  
Michiel Stevens

Here, we review the characteristics and synthesis of magnetic nanoparticles (MNPs) and place these in the context of their usage in the immunomagnetic enrichment of Circulating Tumor Cells (CTCs). The importance of the different characteristics is explained, the need for a very specific enrichment is emphasized and different (commercial) magnetic separation techniques are shown. As the specificity of an MNP is in a large part dependent on the antibody coated onto the particle, different strategies in the coupling of specific antibodies as well as an overview of the available antibodies is given.


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