scholarly journals Gold(i) thiotetrazolates as thioredoxin reductase inhibitors and antiproliferative agents

2015 ◽  
Vol 44 (3) ◽  
pp. 1161-1169 ◽  
Author(s):  
Tatiyana V. Serebryanskaya ◽  
Alexander S. Lyakhov ◽  
Ludmila S. Ivashkevich ◽  
Julia Schur ◽  
Corazon Frias ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Drug Resistant ◽  
Antiproliferative Agents ◽  
Reductase Inhibitors

Gold(i) complexes with thiotetrazolate ligands are potent TrxR inhibitors with activity in drug resistant Nalm-6 cells.

Natural thioredoxin reductase inhibitors from Jatropha integerrima

RSC Advances ◽  
2015 ◽  
Vol 5 (58) ◽  
pp. 47235-47243 ◽  
Author(s):  
Jian-Yong Zhu ◽  
Lan-Lan Lou ◽  
Yan-Qiong Guo ◽  
Wei Li ◽  
Yan-Hong Guo ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Reductase Inhibitors

Nine new diterpenoids were isolated from Jatropha integerrima. The active diterpenoids represent the rare examples of non-aromatic TrxR inhibitors from nature.

Recent Advances in the Development of Thioredoxin Reductase Inhibitors as Anticancer Agents

2012 ◽  
Vol 13 (11) ◽  
pp. 1432-1444 ◽  
Author(s):  
Yang Liu ◽  
Yijing Li ◽  
Shenghui Yu ◽  
Guisen Zhao
Keyword(s):  
Anticancer Agents ◽  
Thioredoxin Reductase ◽  
Reductase Inhibitors ◽  
Recent Advances

Synthesis of 5-Nitro-2-furancarbohydrazides and Theircis-Diamminedichloroplatinum Complexes as Bitopic and Irreversible Human Thioredoxin Reductase Inhibitors

2005 ◽  
Vol 48 (22) ◽  
pp. 7024-7039 ◽  
Author(s):  
Régis Millet ◽  
Sabine Urig ◽  
Judit Jacob ◽  
Eberhard Amtmann ◽  
Jacques-Philippe Moulinoux ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Reductase Inhibitors

Abstract 2444: Effects of GSH depletion and thioredoxin reductase inhibitors on the viability of MDA-MB-231 and MCF-7 cells

2018 ◽  
Author(s):  
Kaci Keleher ◽  
Emma Meetz ◽  
Collin Ellenbecker ◽  
Radek Buss ◽  
Emily Minton ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Reductase Inhibitors ◽  
Mcf 7

Benzimidazol-2-ylidene Gold(I) Complexes Are Thioredoxin Reductase Inhibitors with Multiple Antitumor Properties

2010 ◽  
Vol 53 (24) ◽  
pp. 8608-8618 ◽  
Author(s):  
Riccardo Rubbiani ◽  
Igor Kitanovic ◽  
Hamed Alborzinia ◽  
Suzan Can ◽  
Ana Kitanovic ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Reductase Inhibitors ◽  
Antitumor Properties

Gold(I)N-Heterocyclic Carbene Complexes with Naphthalimide Ligands as Combined Thioredoxin Reductase Inhibitors and DNA Intercalators

ChemMedChem ◽  
2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Andreas Meyer ◽  
Luciano Oehninger ◽  
Yvonne Geldmacher ◽  
Hamed Alborzinia ◽  
Stefan Wölfl ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Carbene Complexes ◽  
Dna Intercalators ◽  
Reductase Inhibitors
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