Multifunctional NaYF4:Yb, Er@mSiO2@Fe3O4-PEG nanoparticles for UCL/MR bioimaging and magnetically targeted drug delivery

Nanoscale ◽  
2015 ◽  
Vol 7 (5) ◽  
pp. 1839-1848 ◽  
Author(s):  
Bei Liu ◽  
Chunxia Li ◽  
Ping'an Ma ◽  
Yinyin Chen ◽  
Yuanxin Zhang ◽  
...  

The NaYF4:Yb, Er@mSiO2@Fe3O4-PEG nanoparticles combining dual-modal diagnostic methods and magnetically targeted anti-tumor therapy were investigated.

2020 ◽  
Vol 20 (4) ◽  
pp. 271-287 ◽  
Author(s):  
Kuldeep Rajpoot

Though modern available cancer therapies are effective, they possess major adverse effects, causing non-compliance to patients. Furthermore, the majority of the polymeric-based medication platforms are certainly not universally acceptable, due to their several restrictions. With this juxtaposition, lipid-based medication delivery systems have appeared as promising drug nanocarriers to replace the majority of the polymer-based products because they are in a position to reverse polymer as well as, drug-associated restrictions. Furthermore, the amalgamation of the basic principle of nanotechnology in designing lipid nanocarriers, which are the latest form of lipid carriers, has tremendous chemotherapeutic possibilities as tumor-targeted drug-delivery pertaining to tumor therapy. Apart from this, it is reported that nearly 40% of the modern medication entities are lipophilic. Moreover, research continues to be efficient in attaining a significant understanding of the absorption and bioavailability of the developed lipids systems.


Nanoscale ◽  
2020 ◽  
Vol 12 (25) ◽  
pp. 13513-13522
Author(s):  
Zhichu Xiang ◽  
Gexuan Jiang ◽  
Di Fan ◽  
Jiesheng Tian ◽  
Zhiyuan Hu ◽  
...  

Tumor-targeted drug carriers are becoming attractive for precise drug delivery in anti-tumor therapy.


Biomaterials ◽  
2012 ◽  
Vol 33 (1) ◽  
pp. 146-162 ◽  
Author(s):  
Lingling Shan ◽  
Sisi Cui ◽  
Changli Du ◽  
Shunan Wan ◽  
Zhiyu Qian ◽  
...  

2016 ◽  
Vol 4 (42) ◽  
pp. 6758-6772 ◽  
Author(s):  
Liangliang Dai ◽  
Junjie Liu ◽  
Zhong Luo ◽  
Menghuan Li ◽  
Kaiyong Cai

The review highlights the main targeted drug delivery systems for tumor therapy, including the targeting sites, strategies, mechanisms and preclinical/clinical trials.


Biomaterials ◽  
2018 ◽  
Vol 155 ◽  
pp. 191-202 ◽  
Author(s):  
Chao-Feng Mu ◽  
Jianliang Shen ◽  
Jing Liang ◽  
Hang-Sheng Zheng ◽  
Yang Xiong ◽  
...  

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